1. Source
Vitamin K2 MK4: mainly from meat
Vitamin K2 MK7: mainly from natto
2. Absorption and transportation
Vitamin K2 (MK-7) is redistributed in the liver mainly through low-density lipoprotein;
Vitamin K2 (MK-4) is carried by the same lipoprotein and is quickly cleared in the liver.
3. Bioavailability
Studies have shown that the side chain of vitamin K2 (MK-7) is longer than that of vitamin K2 (MK-4). Therefore, it can exist in the human body for a longer period of time, and its bioavailability in extrahepatic tissues is higher.
4. Effective usage level
Vitamin K2 (MK-7) belongs to μg/d level (microgram level), once a day, 90 micrograms each time;
Vitamin K2 (MK-4) belongs to the mg/d level (milligram level), 15 mg three times a day (equivalent to 45,000 micrograms per day), and the required dosage is 500 times that of vitamin K2 (MK-7).
5. Production process
Vitamin K2 (MK-7): can be extracted naturally or obtained by chemical synthesis
Vitamin K2 (MK-4): obtained through chemical synthesis
6. Functional use
Vitamin K2 (MK-7): used for osteoporosis, improve arterial calcification, treat Parkinson's disease
Vitamin K2 (MK-4): for osteoporosis
It can be seen that vitamin K2 (MK-7) far exceeds vitamin K2 (MK-4) in terms of biological activity, bioavailability and efficacy.
If you would like to learn more, please contact jason@sxytbio.com
