Description: Cistanche deserticola, Cistanche deserticola is a tall herbaceous plant in the Orobanchiaceae family. Most of Cistanche deserticola grows underground, and the stems gradually become thinner from bottom to top. The leaves are wide ovate, and the upper part of the stem is sparse and narrow, generally lanceolate. The inflorescence is spike-shaped, with petals. The edges are often rolled out, pale yellowish white or lavender, and often turn brown after drying; the fruit is ovoid; the seeds are oval or nearly ovoid, with a net-shaped outside and shiny; the flowering period is from May to June; the fruiting period is from 6 to 8 Moon. Cistanche deserticola is a succulent plant with mild medicinal properties, hence the name Cistanche deserticola.
Function
Anti-aging effect
Cistanche deserticola has a certain degree of anti-aging effect. Cistanche deserticola can significantly enhance the activity of superoxide dismutase (SOD) in mouse red blood cells and significantly reduce the lipofuscin content of mouse myocardium. It can also extend the average life span, half-lethal days and maximum life span of fruit flies. Cistanche deserticola water decoction 8g/kg administered to mice can significantly increase the Na+ and K+-ATPase activities of red blood cell membranes, which may be one of the mechanisms of its tonic effect.
Adjusting endocrine
Promoting metabolism and strengthening effects Cistanche deserticola has an adjusting effect on the decrease and increase in nucleic acid content in the liver and spleen of animals with yang deficiency and yin deficiency; it has the effect of activating the adrenal glands and releasing corticosteroids. Its mechanism of action may be to enhance the hypothalamic-pituitary-ovarian luteinizing function. This effect is not due to their direct stimulation of pituitary luteinizing hormone secretion, but to increasing the pituitary's responsiveness to LRH and the ovary's responsiveness to LH. It is suggested that the main significance of traditional Chinese medicine to nourish the kidneys is to improve the regulatory mechanism in the body and play a positive therapeutic role through the recovery of the body's own internal functions. Through research on the effect of Cistanche deserticola on the DNA synthesis rate of animals with "Yang deficiency", it was found that hydroxyurea inhibits the The reduction reaction of nucleotides at the diphosphorylation level leads to a decrease in the DNA synthesis rate, and disorders of protein and energy metabolism cause "yang deficiency"; Cistanche deserticola may contain a biologically active factor that activates ribonucleotide reductase, and thus can significantly improve The DNA synthesis rate of "yang-deficient" animals can promote the synthesis of RNA; improve the nucleic acid metabolism of proteins; add its dilute ethanol extract to drinking water to feed rats, which can promote growth and development.
The role of the immune system
Cistanche deserticola water extract 50mg/kg or 100mg/kg administered to mice can significantly increase the weight of the spleen and thymus, significantly enhance the phagocytic capacity of peritoneal macrophages, increase hemolysin and PFC values, and improve lymphocyte transformation rate and delayed hypersensitivity index, it can also increase cAMP levels, decrease cGMP levels, and increase the cAMP/cGMP ratio, which may be one of the reasons why it enhances the phagocytic function of peritoneal macrophages. Cistanche deserticola ethanol extract 1.25g/kg, 2.5g/kg (equivalent to 5.61g/kg, 11.21g/kg crude drug) was given to mice by gavage for 8 consecutive days. On the 5th day, sheep red blood cells were used for sensitization, which can significantly inhibit the spleen function. The number of plaques in the cell. Cistanche deserticola extract and epimedium total flavonoids have additive effects on promoting lymphatic circulation in immune-suppressed mice and can enhance the immunity of model mice.
Promote DNA synthesis
Cistanche deserticola decoction (0.5g/ml) administered intragastrically to 0.5ml/mouse can increase the synthesis of DNA in the liver and spleen of mice with "yang deficiency" caused by hydrocortisone acetate.
Other functions
The water extract, ethanol-water extract and ethanol extract of Cistanche deserticola have antihypertensive effects on anesthetized dogs, cats, rabbits, etc. Cistanche deserticola can promote saliva secretion and respiratory paralysis in mice. The component that promotes saliva secretion is some kind of organic acid-like substance, and the component that causes respiratory paralysis may be glycosides.
The rapid extraction process of Cistanche deserticola extract includes the following steps:
Step A: Remove the scaly leaves of fresh desert Cistanche deserticola, cut into thin slices and then microwave dry;
Step B: Crush the dried Cistanche deserticola, and pass the powder through a 60 or 80 mesh sieve;
Step C: After mixing Cistanche deserticola powder and water according to a certain multiple, use flash extraction equipment to carry out water extraction. The internal blade rotation speed of the flash extraction equipment is 15000~30000r/min, and the filtrate is obtained after filtration;
Step D: After mixing the filter residue separated in step C with ethanol according to a certain multiple, alcohol extraction is performed using flash extraction equipment. The inner blade rotation speed of the flash extraction equipment is 15000~30000r/min, and the filtrate is obtained after filtration;
Step E: Combine the filtrate in step C and step D, and prepare the desert meat ash extract after low-temperature vacuum concentration, wherein the vacuum degree is 20~90Kpa, the temperature is 25~50°C, and the concentration time is 0.5~3h.
Preferably, the thickness of the desert Cistanche deserticola flakes is 2~4cm, the microwave frequency is 2000~3000MHz, and the drying time is 15~25min.
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