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Jan 20, 2022

Is Artemisinin The Only Effective Antimalarial Drug?

Artemisinin is the most effective antimalarial drug after pyrimethamine, chloroquine and primaquine, especially for cerebral malaria and anti-chloroquine malaria. The world's only effective malaria treatment."


When it comes to artemisinin, people will first think of its anti-malarial function. WHO believes that artemisinin is the drug with the best effect in the treatment of malaria drug resistance. Combination therapy with artemisinin-based drugs is also the current treatment for malaria. the most effective and important means. However, with the deepening of research in recent years, more and more other effects of artemisinin have been discovered and applied, such as anti-tumor, treatment of pulmonary hypertension, anti-diabetes, embryotoxicity, anti-fungal, immune regulation, etc.



Distribution


Artemisinin is mainly obtained by direct extraction from Artemisia annua, or by extracting artemisinic acid with a high content in Artemisia annua, and then semi-synthetically obtained. Although Artemisia annua is widely distributed around the world, the content of artemisinin varies greatly depending on the place of origin, which has significant ecological significance. According to the research, except for some areas in China, the content of artemisinin in Artemisia annua produced in most regions of the world is very low and has no useful value.


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