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Biotinoyl Tripeptide-1

Biotinoyl Tripeptide-1

Name: Biotinoyl Tripeptide-1/Biotin-GHK
CAS No.: 299157-54-3
Appearance: White powder
Purity: ≥98%
Application: Cosmetics (not for oral use)
MOQ:10g
Storage: Cool, Dry, Away From Light
Payment: T/T,VISA,XTransfer,Alipay......
Shipping Speed: 3-5 days
Certification:cGMP, FSSC22000, BRC, HALAL, KOSHER, ISO9001, ISO22000
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Product Introduction

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of biotinoyl tripeptide-1 in China. With abundant experience, we warmly welcome you to wholesale bulk biotinoyl tripeptide-1 for sale here from our factory. Quality products and reasonable price are available.

 

Product Overview

 

Biotinoyl Tripeptide-1(Biotin-Ghk) is a peptide composed of three amino acids, formed by the combination of Tripeptide-1 and biotin. Combining the properties of both components to produce a synergistic effect, it strengthens hair follicles, stimulates the expression of hair keratin genes, and combats follicle aging, making it a safe and effective active peptide for preventing hair loss.

structure of Biotinoyl Tripeptide-1

Product Details

Items

Standards

Results

Appearance

White powder

Complies

Purity (HPLC)

≥98.0%

99.18%

Water

≤7.0%

4.59%

Acetic acid content

≤20.0%

10.25%

Solubility

≥2mg/ml in water

Complies

 

Product Features

1. Effectively stimulates the synthesis of keratin-a key component of hair-thereby promoting hair growth;
2. Deeply repairs damaged hair, making it thicker and stronger;
3. Features a defined amino acid sequence and a clear mechanism of action;
4. Composed of small-molecule peptides that are easily absorbed and highly compatible with other ingredients;
5. Safer than conventional hair growth agents, causing no irritation or side effects at recommended dosages.

 

Mechanism of Action

 

1. Biotin-Ghk enhances the synthesis of extracellular matrix components-such as collagen IV and laminin-5-thereby delaying follicle aging and improving follicle structure. This promotes hair anchorage within the dermal follicle, stimulates hair growth, and prevents hair loss.

2. It exerts a positive effect on hair follicles by promoting scalp microcirculation and reducing follicle atrophy and aging.

3. It helps slow the aging process by reducing the production of dihydrotestosterone (DHT), thereby improving the condition of the hair follicles.

product-751-519

 

 

Test Results for Biotinoyl Tripeptide-1

 

In a study involving 20 men (mean age: 36.8 ± 9.1 years) using a product containing Biotinoyl Tripeptide-1, standardized scalp photography, hair combing tests, and hair cuticle assessments were conducted at baseline and at 6 and 12 weeks of treatment. The results showed reductions of 7.17% and 13.15% after 3 and 6 months, respectively, with a 26.9% decrease in hair loss at week 12; additionally, 68.5% and 68.4% of patients showed improvement or significant improvement in hair growth at weeks 6 and 12, respectively.

Biotinoyl Tripeptide-1 Research

Another study evaluating the efficacy and safety of a hair serum involved 42 healthy adult male and female volunteers suffering from hair loss, who used the test product daily for 90 days. Significant improvements relative to baseline were observed at both day 60 and day 90. Compared to baseline, hair thinning improved by 7.03% at day 60 and 17.55% at day 90.

Analysis of mean hair density showed significant improvements compared to baseline as early as day 30 and at all subsequent time points. Density increased from 171.35 ± 21.9 hairs/cm² to 185.01 ± 20.57 hairs/cm², representing a 7.97% change.

With continued use of the test product, hair growth rates showed significant improvement at days 30, 60, and 90 compared to baseline. The mean growth rate increased from 306.39 to 359.56 µm/2 days, a change of 17.36%.

Biotinoyl Tripeptide-1 Research

Throughout the study, the percentages of hairs in the anagen (growth) and telogen (resting) phases remained similar; notably, the mean percentages did not decrease.

Measurements of vellus and terminal hair densities showed statistically significant improvements in terminal hair density at all time points compared to baseline. By the final visit, vellus and terminal hair densities had changed by 13.51% and 5.93%, respectively, relative to baseline.

 

Source:

1.Samadi, A., Rokhsat, E., Saffarian, Z., Goudarzi, M.M., Kardeh, S., Nasrollahi, S.A. and Firooz, A. (2024), Assessment of the efficacy and tolerability of a topical formulation containing caffeine and Procapil 3% for improvement of male pattern hair loss. J Cosmet Dermatol, 23: 1492-1494. https://doi.org/10.1111/jocd.16102

2.Majeed M, Majeed S, Nagabhushanam K, Mundkur L, Neupane P, Shah K. Clinical Study to Evaluate the Efficacy and Safety of a Hair Serum Product in Healthy Adult Male and Female Volunteers with Hair Fall. Clin Cosmet Investig Dermatol. 2020 Sep 24;13:691-700. doi: 10.2147/CCID.S271013. PMID: 33061509; PMCID: PMC7522433.

 

Product Application Recommendations

Biotinoyl Tripeptide-1

 

Application: Products designed to strengthen hair and prevent hair loss.

Recommended Ingredient Combinations:
1. Biotinoyl Tripeptide-1 + Copper Tripeptide-1: Strengthens hair follicles and promotes significant hair growth.
2. Biotinoyl Tripeptide-1 + Acetyl Tetrapeptide-3: Highly effective for preventing hair loss; also shows significant results for eyelashes.
3. Biotinoyl Tripeptide-1 + Myristoyl Pentapeptide-4: Promotes eyelash growth and increases density.

4. Biotinoyl Tripeptide-1 + Hexapeptide-11: Reduces hair loss and improves hair condition.

 

Contact Us

 

If you are interested in YTBIO's Biotinoyl Tripeptide-1, please feel free to contact us via online chat or email to obtain the latest price quotes or request samples.

Telephone:+8617782577059
Email:sales@sxytbio.com

 

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