Description
Nuciferine is an aporphine-type alkaloid in lotus leaves and is the main lipid-lowering active ingredient in lotus leaves. It uses sun-dried and crushed lotus leaves as raw materials, uses cellulase pretreatment, dilute hydrochloric acid extraction, It is extracted by a series of methods including ultrasonic assisted extraction and chloroform extraction. Among them, lotus leaves from Shicheng production area in Jiangxi contain the highest nuciferine content.
According to traditional Chinese medicine, lotus leaves are bitter and mild in nature and taste, and belong to the liver, spleen, stomach and heart meridians. It has the effects of clearing away heat and dampness, promoting hair and clearing yang, cooling blood and stopping bleeding. The alkaloids in lotus leaves have medicinal and dietary effects such as lowering blood lipids, fighting free radicals, inhibiting hypercholesterolemia and arteriosclerosis, and also have anti-mitotic effects and strong antibacterial effects.
Nuciferine is an aporphine-type alkaloid in lotus leaves and is the main lipid-lowering active ingredient in lotus leaves. It uses sun-dried and crushed lotus leaves as raw materials, uses cellulase pretreatment, dilute hydrochloric acid extraction, It is extracted by a series of methods including ultrasonic assisted extraction and chloroform extraction. The alkaloids in lotus leaves have the effects of lowering blood lipids and fighting free radicals. They also have anti-mitotic effects and have strong antibacterial effects.
Weight loss effect
1. Nuciferine contains a variety of effective lipid alkaloids, which can effectively decompose fat in the body and powerfully excrete it from the body.
2. Lotus leaf base can be densely packed on the intestinal wall of the human body, forming a layer of fat isolation film, preventing fat absorption and preventing fat accumulation. Detoxify and regulate endocrine.
3. Nuciferine has significant detoxification effect, and can effectively open up various metabolic pathways in the human body, remove free radicals, and regulate the functions of the internal organs.
4. Nuciferine has the effects of clearing heart fire, calming liver fire, purging spleen fire, lowering lung fire, clearing heat and nourishing the mind. It can mediate endocrine, improve human body microcirculation and improve eating habits.
5. Nuciferine improves greasy eating habits. It has a strong oil-repelling effect. Nuciferine accumulates in the human body for a long time, inhibits fat absorption potential signals and inerts the brain's eating nerves, thus making you gradually become disgusted with fishy and greasy food.
Application
Nuciferine is one of the most widely used health care ingredients in reducing lipids, lowering blood pressure, and eliminating cellulite. It is also a "sacred product for reducing lipids" praised by authoritative Western medical societies.
Taking matters
High-purity lotus leaf is a concentrated strong alkaloid, only suitable for people in need (such as obesity, hypertension, hypercholesterolemia, arteriosclerosis, etc.). Note: Take high-purity lotus leaf for health care purposes. Alkali can easily lead to low body fat and malnutrition, so please follow the relevant instructions.
Extraction process
The alkali extracting agent for extracting nuciferine and the method for extracting nuciferine. The alkali extracting agent consists of C1-C5 short-chain alcohols, alkali metal or alkaline earth metal alkali solutions and degreasing solvents; the extraction method of nuciferine is to crush crushed nuciferine. The leaf raw material is extracted with methanol and/or ethanol to obtain an extraction mixture; the obtained extraction mixture is filtered, and the filtrate is concentrated to 1/2 to 2 times the volume of the lotus leaf raw material, left to stand and dried to obtain a crude lotus leaf extract; After the crude leaf extract is crushed, add 5 to 10 times the volume of the lotus leaf crude extract as an alkali extracting agent, stir at 50 to 80°C for 5 to 10 hours, cool and crystallize, filter and dry to obtain crude nuciferine crystals; you will get The crude crystal is obtained after recrystallization; the raw material of the alkali precipitating agent is cheap, which can promote the high yield and high purity crystallization of nuciferine from the solvent. The extraction method is simple to operate and the equipment is conventional equipment, which can be obtained with high yield and high purity. Nuciferine greatly reduces the cost of nuciferine and is conducive to industrial production.
Lotus leaf medicinal effects
Lotus leaf, also known as lotus leaf, is the dry leaf of the lotus plant of the Nymphaeaceae family. It is mild in nature and bitter in taste. It is related to the liver, spleen and stomach meridians. It has the effects of clearing away heat and relieving summer heat, promoting hair and clearing yang, cooling blood and stopping bleeding. "Compendium of Materia Medica" once recorded that "taking lotus leaves can make people lose weight." Modern medicine believes that lotus leaves can effectively reduce blood lipid levels, inhibit weight gain, and prevent cardiovascular and cerebrovascular diseases such as hyperlipidemia, hyperglycemia, and atherosclerosis. Vascular disease.
Lotus leaf bioactive ingredients
According to research, the biologically active substances in lotus leaves are mainly flavonoids and alkaloids. Among them, the alkaloids in lotus leaves (including nuciferine, protonusine, nuciferine, isolixinine, etc.) are good for regulating fat and losing weight. The function is the most significant.
Lotus leaf weight loss principle basis
Lotus leaf alkaloids can be used to lose weight. The main mechanism is: inhibiting lipase activity during the intestinal absorption stage and reducing the body's hydrolysis and absorption of fat; reducing lipid synthesis and improving lipid oxidation metabolism during the human body's utilization stage. The activity of lipase and hepatic lipase prevents fat accumulation, thereby achieving the purpose of lowering fat and losing weight. In addition, there is a lot of fiber in lotus leaves, which can promote intestinal peristalsis, help defecation and remove toxins from the body.
scrape oil and brush grease
Speaking of scraping oil and brushing fat, it must be related to obesity. Obesity is a chronic metabolic disease caused by multiple factors and is an important cause of many diseases such as type 2 diabetes, cardiovascular and cerebrovascular diseases, and malignant tumors. With the rapid development of my country's economy, high calorie intake, unbalanced diet, increased study and work pressure, and reduced physical activity have become the main causes of obesity. Since then, nuciferine has played a very important role.
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