Retinaldehyde Powder

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of retinaldehyde powder in China. With abundant experience, we warmly welcome you to wholesale bulk retinaldehyde powder for sale here from our factory. Quality products and reasonable price are available.

Retinaldehyde, also known as vitamin A aldehyde,all trans Retinal,retinene, is an oxidized derivative of retinol, which is generated by oxidative cleavage of β-carotene, reduced to retinol, and retinoic acid by oxidation. Retinaldehyde is an intermediate metabolite of natural retinoic acid, has similar biological activity as retinoic acid, and the skin's tolerance to it is significantly better than retinoic acid.

Retinaldehyde (RAL), also known as vitamin A aldehyde, is an oxidized derivative of retinol. It is generated by the oxidative cleavage of β-carotene. Retinol is obtained by reduction, and retinoic acid is obtained by oxidation. Retinoic acid (retinoic acid) plays a wide range of roles in skin diseases, but its clinical application is limited to a certain extent due to local irritation. Retinal is an intermediate metabolite of natural retinoic acid and has similar biological activity to retinoic acid, and the skin's tolerance to it is significantly better than that of retinoic acid.

It has the properties of retinoic acid in the skin and is better tolerated than retinoic acid. It directly interacts with protein receptors in cells to stimulate the skin epidermis to accelerate renewal, increase the thickness of the stratum corneum, and make the skin tighter and more orderly; At the same time, it can accelerate the production of collagen in the dermis, prevent UV damage to collagen, inhibit the increase in MMP caused by UV, and make the skin more elastic; the unique aldehyde-based structure has a strong inhibitory effect on Propionibacterium acnes, etc. , effectively improve acne-prone skin.

Retinal has many targets on the skin. When used in skin care products, it can produce multiple effects such as anti-aging, skin rejuvenation, whitening, anti-wrinkle, acne removal, and exfoliation. It is an emerging and highly efficient natural active substance. However, retinal is difficult to dissolve in water and easily oxidized, which limits its application in cosmetics.

It supports sample testing and third-party testing. It has its own factory and many years of production experience. It has advanced equipment and can guarantee product quality and delivery. You can visit the factory. There are good after-sales service and very preferential prices, and there will be different discounts according to different order quantities.

Regarding Retinaldehyde, we have two specifications, namely 6% nano-retinaldehyde and 98%, 6% is a yellow liquid that needs to be stored below 0 degrees Celsius, and 98% is a powder that needs to be stored below -20 degrees Celsius. We have sold a lot of this product including some well-known brands. We use cold chain transportation to ensure the stability of the product during transportation. For more detailed information about this product, please scroll down to the details page. At the end we have retinal The transportation package and more detailed information about the product, if you are interested in this product, please contact us, and there will be professionals about this product to give you detailed answers

Product Details Table

The application of large non-physiological doses of exogenous retinoic acid can cause overloading of retinoic acid-dependent pathways in the skin, resulting in adverse reactions such as skin irritation. RAL is a natural metabolite of retinol and the direct precursor of retinoic acid, which has similar biological activities to retinoic acid. The advantage of RAL compared with retinoic acid is its multidirectional metabolism, that is, excess RAL can be quickly reduced to retinol, and then stored and inactivated in the form of retinol. This "reverse metabolism" Not found in Vitamin A Acid. After it is absorbed by the skin, most of it is converted into retinol vinegar and stored for slow release. A small amount of RAL is oxidized by keratinocytes into retinoic acid in a differentiation-dependent manner, and a very small amount of retinoic acid is released in the skin. It can play a significant biological role within cells. This can avoid adverse skin reactions caused by large doses of Vitamin A Acid. Clinical observations also show that topical RAL cream is better tolerated than Vitamin A Acid and can be applied to sensitive areas. Topical RAL is not absorbed into human blood, and the levels of various retinoids in the blood are not affected.

RAL needs to be converted into retinoic acid by enzymes in keratinocytes before it can take effect, so RAL has similar biological activity to retinoic acid. One of the indicators of retinoic acid activity is the induction of cellular retinoic acid-binding protein (CRABP-2) expression. Topical RAL can significantly induce the expression of CRABP-2 mRNA and protein. Topical application of natural retinoic acid can also induce expression of nuclear retinoic acid receptors. Like retinoic acid, RAL also has the function of regulating cell proliferation and differentiation. It can increase epidermal DNA synthesis, increase epidermal thickness, induce 50kD keratin, and reduce 7OkD keratin mRNA expression. Induces positive keratinization, reduces the expression of 65kD keratin mRNA, and increases the expression of filament aggretin and loricrin mRNA. In addition, RAL is also involved in regulating neovascularization in the skin and inhibiting the production of vascular endothelial growth factor by keratinocytes. Repair UVA-induced elastic fiber and collagen damage. RAL also has comedinolytic and direct bactericidal effects against Propionibacterium acnes. Natural retinoic acid plays an important role in epidermal differentiation, dermal reconstruction and skin inflammation. As an important intermediate metabolite of natural retinoic acid, retinaldehyde has similar biological activity to retinoic acid and is well tolerated by the skin, so it is widely used in cosmetics.

Retinal can repair UV-induced loss of elastic fibers and collagen:

Retinal can combat skin aging caused by ultrasound and fluid technology:

Retinal can effectively improve the symptoms of skin photoaging:

Retinol and retinaldehyde are well tolerated, while retinoic acid is more irritating:

Retinal can effectively inhibit epidermal melanin:

Used in skin care products, it can produce good anti-aging, skin rejuvenation, whitening, anti-wrinkle, acne, and keratin removal effects. It is a new type of highly effective natural active substance.

Add at room temperature Recommended dosage: 1-5%. The optimal pH range of the system is 3.0-6.5. The finished product should avoid direct sunlight (use opaque packaging). It is recommended to add UV absorbers to the day care products.

Product Advantage

Retinaldehyde has many targets in the skin. It can be used in skin care products to produce good anti-aging, skin rejuvenation, whitening, anti-wrinkle, acne, and keratin removal effects. It is an emerging and highly effective natural active.

Our aim is to establish long-term cooperative relations with customers, so we focus on after-sales service and product quality. So far, our products have been exported to various countries and are well received by customers. Our price has an absolute advantage among the peers, and we will have different discounts according to the order quantity.

For more information about Retinaldehyde Powder or other products, please contact:

Email: sales@sxytbio.com
Tel/WhatsApp: +86 177 8257 7059

Combat skin aging caused by ultrasound and fluid technology

Fig. 1. Mean changes from baseline of epidermal thickness (± SEM) on the forehead and the temple, in the retinaldehyde group and the control group. 

Fig. 2. Mean changes from baseline of dermal thickness (± SEM) on the forehead and the temple, in the retinaldehyde group and the control group. 

Fig. 3.Mean changes from baseline of stiffness (± SEM) on the forehead, in the retinaldehyde group and the control group. 

Fig. 4. Mean changes from baseline of elasticity (± SEM) on the forehead, in the retinaldehyde group and the control group.

Effectively inhibit epidermal melanin

Fig. 1.Changes in objective assessments after 12 weeks of application of RAL 0.05% and RAL 0.1% in patients with photoaged skin.Significant increases in hydration (A), reductions in the TEWL (B), and improvements in the fine wrinkle (C) and skin roughness (F) scores were evident in both groups, but the changes did not differ significantly between the groups. The brightness (L* value) improved to a similar extent in both groups (D). A significant improvement in the melanin index was evident only in the RAL 0.1% group (E) 

Noted: Creams of both 0.1% and 0.05%RAL were well tolerated and improved skin moisture and texture. However, only 0.1 % of RAL cream could improve melanin index.

Effectively improve the symptoms of skin photoaging

Fig. 1. Standardized photographs of the crow's feet area in subject of the cream , before and at the end of treatment. A, Change in wrinkle depth. B, Change in skin texture 

Hot Tags: retinaldehyde powder, China retinaldehyde powder manufacturers, suppliers, factory