L-glutathione Powder

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of l-glutathione powder in China. With abundant experience, we warmly welcome you to wholesale bulk l-glutathione powder for sale here from our factory. Quality products and reasonable price are available.

L-Glutathione powder (GSH) is a tripeptide composed of glutamic acid, cysteine and glycine, and contains sulfhydryl groups. Glutathione (GSH) has antioxidant and comprehensive detoxification effects. The sulfhydryl group on cysteine is the active group of glutathione (so glutathione is often called g-SH), which can easily interact with some drugs (such as paracetamol) and toxins (such as free radicals, iodoacetic acid, mustard gas) combined. , lead, mercury, arsenic and other heavy metals), it has a comprehensive detoxification effect. Therefore, glutathione, especially in liver cells, is involved in biotransformation, converting harmful toxins into harmless substances and excreting them from the body. Glutathione also helps maintain normal immune system function

Glutathione is a highly respected dietary supplement in today's health food industry. The cosmetics industry also highly recommends glutathione, mainly because of its whitening, antioxidant and heavy metal chelating functions. There is no upper limit on the amount of glutathione added to skin care products.

• With twelve years of deep-rooted experience in the plant extract and cosmetic raw material industries, we possess extensive industry expertise and a mature supply chain system, ensuring professional capabilities that are both stable and reliable.
• Equipped with our own manufacturing facilities, we maintain strict control over the entire process-from raw material production and quality control to final delivery-thereby guaranteeing product quality and supply stability.
• We have established a comprehensive global presence, including branch offices across Europe and the Americas, effectively streamlining collaboration processes and enhancing operational efficiency.
• Our product portfolio encompasses a complete matrix of glutathione-related offerings; with a comprehensive range of categories, we are well-positioned to meet the diverse procurement needs of various clients.
• We accommodate large-scale bulk orders and batch purchases, catering specifically to the requirements of first-time partners through a variety of flexible cooperation models.
• All products in our lineup are open to independent third-party testing; our quality inspection processes are fully transparent and traceable, ensuring both regulatory compliance and safety in application.

redox activation

Reduced Glutathione exists in the tissues of the body, and it easily transfers H+ to the hydrogen acceptor to produce a reduction effect. It becomes oxidized Glutathione itself, and then is reduced to reduced Glutathione by NADPH in the tissue, so it plays an important role in the redox effect of the organism. Role.

enzyme activation

After SH-containing enzymes (Carboxylase, Monoaminoxydase, Transaminase, Lipase Trypsin, etc.) are oxidized, most of them become inactive S-S type. The S-S type enzyme is reduced to -SH type and is activated again.

Effect on patients with liver disease

Liver disorders can cause various metabolic disorders. Glutathione is related to metabolism and can improve liver dysfunction caused by liver disorders.

Anti-allergic effect

Allergic symptoms occur due to the intervention of chemical intermediary substances such as Histamine, Acetylcholine, Serotonin, Bradykinin, etc.

anti-oxidation

Glutathione is a natural reducing agent in living organisms and can be easily oxidized into GSSG, thereby protecting other substances from being oxidized. It can scavenge free radicals in the body, such as hydrogen peroxide, peroxide free radicals, etc., and protect sulfhydryl groups in proteins from being oxidized. It is oxidized, repairs the sulfhydryl groups in the damaged protein, restores the active function of the protein, prevents cell hemolysis, promotes the reduction of methemoglobin, and relieves discomfort caused by hypoxemia, nausea and liver disease.

Detoxify

Glutathione has a certain detoxifying effect on the poisoning of carcinogens such as carbon monoxide, heavy metals, organic solvents, and epoxy compounds, and can be combined with them to be excreted from the body; it also has an effect on leukopenia caused by radiation, radioactive drugs, or anti-tumor drugs. It has a protective effect; it also has a detoxifying effect on various carcinogens by helping the liver metabolize, such as aflatoxin, etc.

Prevention and treatment

Glutathione can be used to protect the liver and promote liver detoxification. It is often used to treat liver diseases such as alcoholism, cirrhosis, hepatitis, and fatty liver. Long-term use of glutathione can inhibit the formation of alcoholic fatty liver.

Glutathione is also beneficial to the maintenance of corneal and lens transparency, tissue repair and regeneration, and can also be used to treat progressive cataracts, corneal diseases and retinal diseases.

Whitening

Glutathione can reduce tyrosinase activity in three different ways.

1. Tyrosinase is directly inhibited by sulfhydryl chelating copper sites.

2. Glutathione interferes with the cellular transfer of tyrosinase to promelanosomes, which are a prerequisite for melanin synthesis.

3. Third, the inhibition of tyrosinase is achieved indirectly through its antioxidant effect. Glutathione transfers melanogenesis from eumelanin to pheomelanin synthesis via a reaction between sulfhydryl groups and dopaquinone, resulting in the formation of sulfhydryl-dopa conjugates. Glutathione has powerful antioxidant capabilities and has been shown to scavenge the production of reactive oxygen species in epidermal cells induced by ultraviolet radiation.

Enhance enzyme activity

Glutathione protects the -SH group in the enzyme molecule, which is beneficial to the enzyme activity, and can restore the active function of the -SH group in the enzyme molecule that has been destroyed, so that the enzyme can regain its activity. Glutathione can also inhibit fatty liver caused by ethanol's damage to the liver.

Protect blood cells

Glutathione can also protect hemoglobin from oxidation such as hydrogen peroxide and free radicals, allowing it to continue to function normally in its ability to transport oxygen. Human red blood cells contain a lot of glutathione, which is of great significance for protecting the sulfhydryl groups of proteins on red blood cell membranes from being in a reduced state and preventing hemolysis.

Fight free radicals

Excessive free radicals produced by the body's metabolism will damage biological membranes, attack life macromolecules, and accelerate the aging of the body. The main physiological function of glutathione is to remove free radicals in the human body. As an important antioxidant in the body, it protects the body. Sulfhydryl groups in many molecules such as proteins and enzymes.

Adding glutathione to food can play an unexpected role:

1. Adding to noodle products can play a reducing role. It not only shortens the time for making bread to one-half or one-third of the original, but also greatly improves the working conditions, and plays a role in strengthening food nutrition and other functions.

2. Add it to yogurt and baby food, which is equivalent to vitamin C, which can act as a stabilizer

3. Mix it into the fish cake to prevent the color from deepening.

4. Adding to meat products and cheese and other foods has the effect of intensifying flavor

The whitening mechanism of glutathione:

Reduced l glutathione powder can reduce tyrosinase activity in three different ways. Tyrosinase is directly inhibited by sulfhydryl chelating copper sites. Secondly, glutathione interferes with the cell transfer of tyrosinase to premelanosomes, which is a prerequisite for melanin synthesis. Third, the inhibition of tyrosinase is achieved indirectly through its antioxidant effect. Glutathione transfers melanogenesis from eumelanin to pheomelanin synthesis through the reaction between sulfhydryl and dopaquinone, resulting in the formation of sulfhydryl-dopa conjugates. Glutathione has a strong antioxidant capacity and has been proven to eliminate the reactive oxygen species produced in epidermal cells induced by ultraviolet radiation.

Skin care products field

Glutathione is well known for its benefits as a skin care product. As an antioxidant factor, GSH has the spirit of "giving up the small self for the greater self". It is actively oxidized by free radicals and converted into inactive GSSG, which is degraded by macrophages, thus protecting the integrity of cells. Not only that, when it comes to fighting melanin, glutathione also has its own unique mechanism of action, which can block the activity of tyrosinase and achieve whitening effects from the root. In addition, it has the effect of repairing damaged cells and improving the delicateness and smoothness of the skin.

Medical beauty field

Glutathione is the main ingredient in the medical beauty product "whitening injection". In addition, the medical beauty product "whitening injection" is mainly made of hyaluronic acid, glutathione and other products in a scientific ratio. It has whitening and anti-aging properties. Oxidation and inhibition of melanin. When adding glutathione ingredients to water-light injections, be sure to let a professional doctor do the mixing and operation. When injecting whitening injections, the ingredients are only injected into the dermis layer and cannot enter the muscle layer, making the treatment of deep dynamic lines ineffective and can only temporarily treat epidermal fine lines.

Health products

GSH can participate in biological transformation, excrete harmful substances from the body, help maintain normal immune function and other functions; protect your own liver, heart, etc.

For more information about L-glutathione Powder or other products, please contact:

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Determination of Content

1.1 Instrument and Equipment

High Performance Liquid Chromatography (HPLC)

Chromatographic Work Station (N2010)

1.2 The Condition of Instrument

Chromatographic Column: Ｃ18 150×4.6ｍｍ+ Guard Column

Column Temperature: 29.8℃

Flow Velocity: 0.8ml/min

Detection Wavelength: 214nm

Sample Amount: 20ul

1.3 Reagent and Solution

Trifluoroacetic Acid (TFA)

Acetonitrile(CH3CN)

Buffer Solution A: 0.1% TFA,H2O

Buffer Solution B: 0.1%TFA,CH3CN

Mobile Phase C: A:B=95∶5 (volume ratio)

1.4 Test methods

Sample and reference material of Glutathione Reduced Accurately weigh 0.25g

(accurate to 0.0002g) , add buffer A and dilute to 1000ml volumetric flask, and

perform liquid chromatography analysis within half an hour.

1.5 The results calculated

The content X1 (expressed in weight percent) is calculated according to formula (1)

In the formula,

A1-Sample absorption peak area,uv×s;

A2-reference material absorption peak area,uv×s;

m1-Weigh the sample in grams,g;

m2-Weigh the reference material in grams,g;

X2-Loss On Drying of sample,percentage by weight(%)

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