Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of madecassoside in China. With abundant experience, we warmly welcome you to wholesale bulk madecassoside for sale here from our factory. Quality products and reasonable price are available.
Product Description
Madecassoside is the core active triterpenoid saponin from Centella asiatica, possessing enhanced hydrophilicity and skin permeability. It appears as a white to off-white crystalline powder, readily soluble in water and ethanol. The mechanism of action of Madecassoside focuses on inhibiting inflammatory pathways, rapidly relieving skin redness, stinging, and itching. Simultaneously, it promotes the expression of stratum corneum barrier-related proteins, accelerating skin barrier repair.
Madecassoside is commonly found in emergency serums, soothing creams, post-medical aesthetic dressings, and baby skincare products. YTBIO supplies Madecassoside in purity levels (80%-90%), suitable for various formulations including serums, freeze-dried powders, creams, and sprays. Fully certified, it supports sample testing and flexible MOQs.
Molecular Structure
Test report
Product Function
Antioxidant Protection
Proven to visibly reduce skin-damaging free radicals formed by factors such as exposure to UV light or environmental pollution
Anti-inflammatory properties
Small preliminary studies suggest that it can reduce inflammatory cell messengers called cytokines, including those normally activated during acne outbreaks, making the ingredient beneficial not only for those with dry or sensitive skin, but also for those prone to acne The skin is also beneficial.
Improves skin hydration
Laboratory studies show that madecassoside can increase the skin's natural hyaluronic acid production.
Provides additional anti-aging benefits
Laboratory studies have shown that it can enhance collagen synthesis. And, going back to those antioxidant properties mentioned earlier, it works in tandem with vitamin C, a proven anti-aging agent. A small clinical study in 20 female patients showed that six months of topical vitamin C and madecassoside improved wrinkles, skin firmness and texture, and skin hydration.
Anti-oxidize effect
It has strong antioxidant capacity, can neutralize free radicals, and reduce cell damage to oxidative stress. This helps to prevent the occurrence of various chronic diseases, such as cardiovascular and cerebrovascular diseases, aging and so on.
Anti-inflammatory effect
It has obvious anti-inflammatory effect and can inhibit the release of inflammatory response and inflammatory mediators. Therefore, it has potential applications in alleviating inflammation-related diseases, such as arthritis, gingivitis, and skin inflammation.
In an animal experiment, researchers successfully established an atopic dermatitis (AD) model in mice by repeatedly applying DNCB (a chemical that induces allergic reactions) to the ears. After two weeks, the ear thickness of the model mice increased 2.4 times compared to normal mice, and they exhibited typical AD symptoms such as bleeding, edema, abrasions, and scaling. Treatment with Centella asiatica extract (CA) showed significant improvement.
Ear swelling was reduced: The ear thickness of mice in the CA treatment group was reduced by 1.2 to 1.3 times compared to the model group.
Lymph node enlargement was alleviated: The lymph node weight of AD model mice increased 12.4 times, while the lymph node weight of mice in the CA treatment group was significantly reduced by 1.6 times, approaching normal levels.
Skin lesions were improved: CA treatment effectively reduced skin lesions such as bleeding, edema, abrasions, and desquamation.
These results indicate that Centella asiatica extract can effectively alleviate allergy-induced atopic dermatitis-like symptoms and has the potential to inhibit skin inflammation, reduce tissue swelling, and regulate immune responses.
Beauty anti aging
Can promote the synthesis of collagen, increase skin elasticity, improve wrinkles and fine lines. It also reduces the formation of melanin, lightens dark spots, brightens skin tone, and makes skin more youthful and smooth.
Antibacterial effect
It has inhibitory effect on a variety of bacteria, especially has high activity on pathogenic bacteria and drug-resistant bacteria, and may help to treat infectious diseases, such as oral infection, skin infection and digestive tract infection.
Immunomodulatory
It can regulate the function of the immune system, enhance the body's immunity and improve resistance. This has important implications for preventing colds, allergies, and autoimmune diseases, among other things.
Product Application
I. Cosmetics and Skincare Products
Amyotrophic asiatica extract, with its anti-inflammatory, antioxidant, and skin-repairing properties, has become a popular active ingredient in skincare products. Common product forms include serums, masks, and repair creams, suitable for sensitive skin care, acne scar and blemish improvement, whitening, and anti-photoaging.
II. Pharmaceuticals and Clinical Treatment
In the pharmaceutical field, amaminidoxylate is primarily used for tissue repair and as an adjunct treatment for inflammation-related diseases. It helps with wound healing and helps relieve symptoms of arthritis, skin inflammation, and other conditions.
We support for buyers:
* Sample is available upon the buyer requirements to test
* Detection by third party
* Document set
* Fast delivery
* After service
* Visit the factory
If you are interested in YTBIO's Centella Asiatica series products or other raw materials, please feel free to contact us via online consultation or by email. We will provide you with professional technical support and customized solutions.
Telephone：+8617782577059
Email：sales@sxytbio.com
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