Hexylresorcinol Powder

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of hexylresorcinol powder in China. With abundant experience, we warmly welcome you to wholesale bulk hexylresorcinol powder for sale here from our factory. Quality products and reasonable price are available.

YTBIO supplies 99% high-purity Hexylresorcinol Powder (4-Hexylresorcinol) to customers worldwide; our high-quality raw materials meet your requirements for purity and standardization. We currently hold substantial stock and can provide technical documentation, including COA and MSDS. Please contact us for product details, samples, and the latest price quotes.

Why Choose YTBIO?

• 99% High Purity: Clearly defined purity specifications to facilitate your formulation process.
• Documentation: Technical documentation, including COAs and MSDSs, is available.
• Formulation Support: We offer application advice tailored to your target product dosage forms and formulations.
• Extensive Experience: With 12 years of deep expertise in the production and export of functional ingredients, we operate our own 10,000-square-meter factory and maintain ample stock. Please feel free to contact us with any questions.

Hexylresorcinol (HR or 4-Hexylresorcinol) is a derivative of resorcinol. Initially used as a food additive to prevent browning in crustacean seafood such as shrimp and crabs, it was later adopted as an active skin-whitening ingredient in cosmetics due to its potent tyrosinase-inhibiting properties and high safety profile.

Product Features

Primary Use: Food-grade antimicrobial agent
Core Function: Confirmed by numerous experiments as one of the most potent tyrosinase inhibitors
Safety: A safe ingredient; gentle and non-irritating for topical use
Advantages: Multi-pathway brightening + anti-aging + anti-inflammatory + anti-glycation effects
Molecular Weight: Low molecular weight; excellent skin penetration

1. Highly Effective Tyrosinase Inhibition：Hexylresorcinol Powder acts directly within melanocytes to potently inhibit tyrosinase activity and reduce melanin synthesis. Compared to some other brightening ingredients, it delivers superior melanin-inhibiting results even at lower concentrations.

2. Antioxidant Capability：It possesses free-radical scavenging abilities, protecting against UV-induced oxidative stress and reducing photo-induced skin darkening.

3. Improves Hyperpigmentation and Fades Acne Marks：Hexylresorcinol inhibits pigment formation and accelerates the restoration of an even skin tone, proving particularly effective at fading dark acne marks.

4. Evens Skin Tone and Fades Dark Spots：Beyond inhibiting tyrosinase, Hexylresorcinol intervenes in melanin synthesis through multiple pathways, enhancing the overall effectiveness of evening skin tone and fading dark spots.

5.Anti-glycation：Glycation is a process in which sugars bind to proteins to form Advanced Glycation End-products (AGEs), leading to skin yellowing, dullness, and a loss of elasticity. 4-HR exhibits anti-glycation activity and reduces the accumulation of AGEs; it not only fades dark spots but also improves overall skin tone by addressing sallowness and dullness.

A study published in the *International Journal of Cosmetic Science* validated the synergistic effects of combining 4-hexylresorcinol (4-HR) with niacinamide through a combination of *in vitro* cell/3D skin model assays and human clinical split-face, double-blind trials.

*In vitro* experiments utilizing primary human epidermal melanocytes and 3D pigmented skin models confirmed that 4-HR is a potent tyrosinase inhibitor; when combined with niacinamide-which blocks melanosome transfer-it produces a significant synergistic effect.

In a 12-week, randomized, double-blind, split-face clinical trial involving Chinese subjects, researchers compared the combination regimen against niacinamide alone, comprehensively evaluating improvements in pigmentation brightness (L* value), crow's feet and perioral lines, skin hydration, and firmness.

The results demonstrated that the combination of 4-HR and niacinamide significantly outperformed niacinamide alone across key metrics-including fading pigmentation, enhancing skin brightness, improving fine lines and wrinkles, and restoring skin firmness. Furthermore, the combination showed excellent safety, with no associated adverse reactions. Pairing 4-HR with niacinamide delivers brightening and anti-aging benefits that surpass those of either ingredient used individually.

Reference:Shariff R, Du Y, Dutta M, Kumar S 5th, Thimmaiah S, Doraiswamy C, Kumari A, Kale V, Nair N, Zhang S, Joshi M, Santhanam U, Qiang Q, Damodaran A. Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide. Int J Cosmet Sci. 2022 Feb;44(1):103-117. doi: 10.1111/ics.12759. Epub 2022 Feb 1. PMID: 34958693; PMCID: PMC9305876.

Hexylresorcinol is a safe ingredient increasingly used in cosmetics; it offers multiple benefits, including skin brightening, antimicrobial properties, and anti-aging effects. As an oil-soluble ingredient, it is commonly found in brightening serums, dark spot-fading lotions, and facial creams.

 

Advantages

• Potent inhibition of melanin production
• Good stability
• Effective at low concentrations
• Excellent compatibility; can be combined with various brightening and repairing ingredients

Recommended concentration: 0.2%–0.5%
Suitable for: All skin types, including sensitive skin

 

Combination Recommendations

+ Tranexamic acid: For fading dark spots

+ Panthenol + Bisabolol: To reduce irritation and provide repair and soothing effects

+ Vitamin C derivatives: For antioxidant benefits and enhanced brightening.

Not recommended: Combining with high concentrations of pure acids or pure retinol, as this may damage the skin barrier and cause stinging or peeling.

If you are looking for a high-quality supplier of 99% Hexylresorcinol Powder raw material, please contact us for detailed specifications, a COA, samples, and bulk pricing; our professional sales team will respond to you within 24 hours.

Telephone/WhatsApp：+8617782577059

Email：sales@sxytbio.com

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