Product description
Glucuronic acid is a uronic acid formed by the oxidation of the C-6 hydroxyl group of glucose to a carboxyl group. D-glucuronic acid generally does not exist in free form because this form is unstable, but in the more stable 3,6-lactone form of the furan ring. D-glucopyranuronic acid is present in oligosaccharides at the junctions of glycosaminoglycan chains.
D-glucuronic acid The source of glucuronic acid in the body is D-glucose. The latter first generates α-D-glucose-1-phosphate in the metabolic process, which is catalyzed by uridine diphosphate glucose pyrophosphorylase (CUDPG pyrophosphorylase) to UDP-α-D-glucose (UDPG) , and then catalyzed by UDPG dehydrogenase to become UDP-α-D-glucuronic acid (UDPGA). The latter, through the action of glucuronyl transferase, transfers the glucuronyl group to foreign chemicals for binding. Because of the extremely abundant glucose storage in the body, this binding is the most common in the second phase reaction. And the most important reaction.
D-glucuronic acid is widely distributed in the animal and plant kingdoms. D-glucuronic acid usually exists in the form of glycoside combination with sugar phenols and alcohols. Such glucuronides are formed in the liver to detoxify toxic hydroxyl-containing substances.
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