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Nov 19, 2020

What Functions Does Astragaloside IV Have?

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Astragaloside Iv, a cycloalting triterpenoid saponin compound, is one of the main effective components of Astragalus membranaceus, and its content is the main standard to evaluate the quality of astragalus membranaceus. Astragaloside IV has a wide range of pharmacological effects including anti-tumor, anti-inflammatory, antioxidant, hypoglycemic, myocardial protection, disease-resistant toxic myocarditis, brain tissue protection, and anti-hepatitis B virus Chemicalbook.


Immunomodulatory effects

Organ protection effects

Reduce the blood sugar effect

Inhibitor of apoptosis effect

Anti-inflammatory and antiviral effect

Anti-aging effect

Promote cell proliferation


_As a major active ingredient extracted from Astragalus membranaceus (ASTRagalus membranaceus), it has broad application prospects, especially in modern high-incidence and high-risk diseases such as cardiovascular diseases, digestive diseases and cancers, and can be developed and utilized as a drug Chemicalbook. The protective effect of astragaloside IV includes cardiovascular system, immune system, digestive system and nervous system, and its mechanism of action is related to the regulation of calcium balance, anti-oxidation, anti-apoptosis, anti-virus and so on.


The content of Astragaloside IV in Astragalus is very low. Currently, the traditional extraction processes of astragaloside IV, such as decocting water and decocting reflux ethanol, have the disadvantages of high extraction temperature, low extraction rate and time-consuming extraction. The latest extraction technologies include high-speed centrifugation, microwave-assisted Chemicalbook extraction, ultrasonic extraction, ultrafiltration, supercritical fluid extraction, ultra-high pressure extraction, and high-speed countercurrent extraction. The new extraction technology plays an important role in improving the extraction rate of astragaloside IV, shortening the extraction time and preventing the destruction of active components.


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