I,Source and origin of pterostilbene
Pterostilbene is a chemical component contained in rosewood, but scientists have also discovered the presence of pterostilbene in other plants. However, because it was first discovered with the species of rosewood, it was named pterostilbene. Pterostilbene is a white or off-white powder crystal with rich medicinal value. It is an antifungal active ingredient in blood-dried blood products and has certain effects on the treatment of hypertension and hyperlipidemia. Pterostilbene is the antifungal active ingredient in blood-drainage products. It is a polyhydroxy stilbene compound and a homologue of resveratrol. In addition to being partially similar to resveratrol in its pharmacological effects, it also has strong Antifungal activity (its antifungal activity is five times that of resveratrol).
II,The nutritional components of Pterostilbene
Pterostilbene is rich in various nutrients, including vitamins, amino acids and polysaccharides. These ingredients provide rich nutrients for the human body, and have the functions of regulating body functions and enhancing immunity.
III, Efficacy of pterostilbene
1. Anti-aging Pterostilbene is rich in antioxidant substances, such as flavonoids and vitamin C, which can neutralize free radicals in the body, inhibit cell aging, and delay the aging process.
2. Improving immunity Pterostilbene has an immune regulating effect, which can enhance the body's immunity and improve disease resistance. It can increase the number and activity of white blood cells, promote the proliferation of lymphocytes, and improve the level of antibodies in the body, thereby enhancing immune function.
3. Lower blood sugar, anti-diabetes
The polysaccharide in pterostilbene has the effect of lowering blood sugar, can regulate the secretion of insulin, improve the sensitivity of insulin, thereby lowering the blood sugar level, and has the effect of auxiliary treatment of diabetes
4. Promote blood circulation Pterostilbene can promote blood circulation, improve microcirculation disorders, increase the elasticity and permeability of capillaries, thereby improving blood supply and oxygen supply, and improving cardiovascular and cerebrovascular diseases.
5. Reduce inflammation Pterostilbene has anti-inflammatory effect, can inhibit inflammation, relieve inflammation symptoms, and reduce pain and discomfort caused by inflammation.
IV,What is Pterostilbene
Pterostilbene, a compound found in many fruits, has many health benefits, including anti-hypertriglyceridemic, anti-hypercholesterolemic. Blueberries, cranberries and red grapes generally contain some amount of pterostilbene. Regular consumption of these fruits and other foods containing this chemical can help reduce the risk of heart disease and may also help strengthen memory function.After years of experiments on animals, American scientists found that the compound extracted from blueberries and grapes can inhibit an enzyme called P450 cytochrome, which can activate chemical carcinogens, and can reduce low-density lipoprotein cholesterol. Rosewood stilbene is a aromatic hydrocarbon called "styrene", which is a derivative of resveratrol. In the early 1990s, American scientists found that resveratrol has the function of preventing heart disease, and it is found in large quantities in red grape skin.
V,Pterostilbene &Resveratrol
Pterostilbene - has some of the similar mechanisms of resveratrol, is a more effective dimethylated derivative, has the best absorption, Pterostilbene has a methylated stilbene molecule similar to resveratrol structure, the only difference is that Pterostilbene molecules replace resveratrol molecules on the hydroxyl group, because Pterostilbene has two methoxy-methylation, It is also more superior in oral absorbance and may be a more potent antioxidant. Resveratrol supports cell apoptosis and is an important factor in affecting the targeted migration of stem cells from blood to tissue. However, Rosewood can down-regulate the expression of iNOS and COX-2 genes, which can support the health of tissue
The effect of resveratrol at low concentration is greater than the anti-inflammatory effect of resveratrol. Rosewood is also a phytoantitoxin (phytochemical defense) similar to resveratrol, belonging to the stilbene molecule, named Rosewood plant genus..
VI.The Effect in Skin Care:
1. Inhibit melanin. Pterostilbene has a strong ability to inhibit melanin, even surpassing that of glabridin, known as "whitening gold", and has a highly effective freckle removal effect.
2. Inhibit tyrosinase. Tyrosinase is the key enzyme of melanin synthesis. Glabridin, known as "whitening gold", has the lowest half inhibitory concentration IC50 value of tyrosinase among all products. Pterostilbene is slightly lower than glabridin, but It is obviously superior to other whitening raw materials such as VC and arbutin.
3. Antioxidant. Free radicals are everywhere, both internally and externally. When the free radicals in the human body exceed a certain amount, they will cause various damages to our body. Free radicals in the air will directly attack the skin, snatch electrons from skin cells, make the skin lose its elasticity, cause rough aging and wrinkles, and aggravate the oxidative damage of the skin. Pterostilbene has excellent antioxidant properties. Its oxygen free radical absorption ORAC value is as high as 12508μmol trolox equivalents/g, which is 3 times that of Vc and glabridin; its ability to inhibit DPPH free radicals is slightly lower than that of Vc.
4. Resist ultraviolet rays. The pterostilbene-treated and untreated mouse fibroblasts were respectively irradiated with ultraviolet rays, and the ability of pterostilbene to resist ultraviolet rays was known by detecting the activity of fibroblasts.
5. Anti-inflammatory effect. There are some destructive enzymes in the human body, such as elastase and collagenase, which will destroy the skin structure, make the skin loose and aging. Pterostilbene possesses dual inhibitory abilities, inhibiting two destructive enzymes at the same time.
6. Anti-glycation. The glycation reaction in the skin area refers to the excessive accumulation of reducing sugars in the skin due to the slow metabolism. The sugars are easy to react with collagen and elastin in the skin to form irreversible brown terminal glycation products (AGEs). Collagen or elastin is denatured and cross-linked, and the skin becomes wrinkled, rough and dark yellow. Pterostilbene can reduce the content of cross-linked proteins, inhibit the glycation reaction, reduce the production of AGEs, and achieve the effect of dispelling jaundice and anti-aging.
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