Dihydroxyacetone (DHA), whose chemical name is 1,3-dihydroxy-2-acetone, is a commonly used cosmetic ingredient with the functions of skin moisturizing, self-tanning and hair coloring. Currently, DHA is not within the regulatory scope of the EU Cosmetic Regulation (EC) No.1223/2009. In 2008, the European Scientific Committee on Consumer Safety (ScientificCommitteeonConsumerSafety, SCCS) received a set of application materials from companies to support the safety of DHA as a cosmetic ingredient. Its research data shows that DHA in concentrations up to 10% is safe to use in cosmetics as a tanning agent. In addition, DHA at concentrations up to 14% is safe to use as a tanning agent in spray cosmetics. In May 2019, SCCS received another application to evaluate the safety of DHA with a concentration of not more than 6.25% when used as a hair dye in leave-on (non-oxidative) hair dyeing cosmetics. According to the safety evaluation data of toxicokinetics, skin irritation and sensitization, acute toxicity, reproductive toxicity, mutagenicity, carcinogenicity and other safety evaluation data provided by the enterprise, the European Scientific Committee on Consumer Safety (SCCS) came to the following conclusion after evaluation: the concentration does not More than 6.25% DHA is safe to use in leave-on (non-oxidative) hair coloring cosmetics as a hair coloring ingredient. Leave-on (non-oxidative) hair-dyeing cosmetic products containing DHA at a
concentration of not more than 6.25% as a hair-coloring ingredient are considered safe when used in combination with a tanning lotion or a cream with a concentration of not more than 10% DHA.
1,3-Dihydroxyacetone can be used in the following fields:
1. Dihydroxyacetone used in the cosmetic industry is mainly used as a formula raw material for cosmetics, especially as a sunscreen with special effects, which can prevent excessive evaporation of skin moisture, and play the role of moisturizing, sun protection and UV radiation protection. In addition, the ketone functional group in DHA can react with the amino acids and amino groups of skin keratin to form a brown polymer, which makes people's skin produce an artificial brown color, so it can also be used as a sun-tanned skin tone simulator, resulting in a similar appearance to the skin. Prolonged exposure to the sun results in a brown or tan skin that looks beautiful.
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