Glabridin is a natural whitening agent isolated from licorice flavonoids. Licorice flavonoids are extracted from the rhizomes of specific varieties of licorice plants (such as glycyrrhiza uralensis, glycyrrhiza inflata, glycyrrhiza glabra, etc.). Pollution, without any side effects to the human body. It is a reddish brown powder at room temperature, insoluble in water, but easily soluble in organic solvents, such as ethanol, propylene glycol, 1,3-butanediol, etc.
Glabridin has a strong antibacterial effect, prevents inflammation, pigmentation and rough skin caused by ultraviolet rays, can remove superoxide ions, inhibit hemolysis caused by hydrogen peroxide, it can inhibit the activity of tyrosinase, and can Inhibiting the interconversion of dopa pigment and the activity of DHICA oxidase, it is a fast, efficient, green whitening and freckle cosmetic additive. It has the ability to scavenge oxygen free radicals similar to SOD (superoxide dismutase). Vitamin E has similar anti-oxygen free radical ability. In addition, Glycyrrhizin also has a strong oxidative effect, anti-atherosclerosis and has a certain effect of lowering blood lipids and blood pressure.
Glabridin is one of the main flavonoids in Glycyrrhiza glabra. It shows strong anti-radical oxidation effect in the cytochrome P450/NADPH oxidation system, and can obviously inhibit the free radicals generated in the metabolism process in the body to protect against oxidation-sensitive biological macromolecules (low density lipoprotein LDL, DNA) and cell walls are oxidatively damaged by free radicals. It can prevent certain pathological changes related to free radical oxidation, such as atherosclerosis, cell senescence and so on. In addition, Glycyrrhizin still has a certain effect of lowering blood fat and blood pressure.
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