What is Povidone iodine
Povidone iodine is a loose complex composed of elemental iodine and a polymer carrier. Povidone acts as a carrier and solubilizer. It is yellow-brown to brown-red amorphous powder at room temperature. Slightly odorous, easily soluble in water or ethanol, the aqueous solution is acidic, and insoluble in ether, chloroform, acetone, ethane and carbon tetrachloride. Povidone-iodine aqueous solution does not have the disadvantages of iodine tincture, has light coloring, is easy to wash off, has little irritation to mucous membranes, does not require ethanol deiodination, has no corrosive effect, and has low toxicity.
Povidone-iodine functions and uses
It is a broad-spectrum, powerful bactericidal disinfectant that has a strong killing effect on viruses, bacteria, fungi and mold spores. This product has little irritation to the skin, low toxicity and long-lasting effects. Safe and easy to use. It is basically non-irritating to tissues and is used for skin and mucous membrane disinfection, such as cleaning before surgery and disinfecting surgical sites and wounds.
Povidone-iodine, generally made into a 10% solution, is used as a disinfectant. Effectively kills: Newcastle disease, bursa of Fabricius, avian influenza, mycoplasma, E. coli, salmonella, influenza, PRRS, etc. It can also kill eggs of livestock and poultry parasites and inhibit the breeding of mosquitoes, flies and other insects. And can be used in fruit trees, crops, fish and shrimp farming.
Features of povidone-iodine
Compound PVP-Ⅰ is a new type of highly efficient disinfectant and antiseptic. A 0.7% to 10% solution can release 1.8 to 24 ppm of free iodine in water, killing microorganisms through the oxidation of the latter. The killing effect of bacteria is better than that of Xianbitai, and it has certain lethality to bacterial spores. The drug has significant killing effect on Candida albicans, Staphylococcus aureus, Escherichia coli, Bacillus subtilis, etc.; the sterilization time of Pseudomonas aeruginosa and Candida albicans is similar to that of compound iodine solution and iodine tincture of the same concentration, but the toxicity is only It is 1/4~1/9. Compound PVP-Ⅰ has no toxic side effects, is low-priced, has a protective function for mucous membranes and skin, and its anti-STD effect is significantly better than Jieryin and potassium permanganate aqueous solutions.
The iodine is gradually released in the solvent and plays a slow-release role to maintain the bactericidal power for a longer period of time. Its powerful bactericidal mechanism is to oxidize the active groups of the protoplasmic proteins of pathogens and combine with the amino groups of proteins to denature them, thereby effectively killing pathogens such as bacteria, spores, fungi, viruses and protozoa. It has the characteristics of strong bactericidal power, wide sterilizing range, minimal irritation, light yellowing, easy cleaning, and no allergic reaction.
It has a rapid killing effect on hundreds of bacteria and viruses such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae, Candida albicans, etc. This product is currently the first choice disinfectant and antiseptic for direct use on human skin and mucous membranes at home and abroad.
Works by gradually breaking down free iodine. Among them, 80%-90% of the bound iodine can be depolymerized into free iodine, which can directly denature and precipitate the proteins in the pathogen, causing the death of the pathogen cells, thereby achieving the purpose of efficient disinfection and sterilization. It is characterized by strong bactericidal power, low toxicity, and is a broad-spectrum bactericide that can kill viruses, bacteria, spores, fungi and protozoa. It has a strong killing effect on Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Treponema pallidum, Hepatitis B virus, HIV, Trichomonas vaginalis, etc.
External use can cause skin allergic reactions and be irritating to the skin and mucous membranes. Use on severely burned or large-area peeled skin can cause systemic adverse reactions, such as metabolic acidosis, hypernatremia and renal function damage. People who are allergic to iodine or have burns with an area greater than 20% should not apply it locally. It is not suitable for patients with toxic colloid thyroid tumors. Pregnant women and newborns should be cautious when using it in large areas. Not recommended for children under 4 years old.
It has a wide bactericidal spectrum and strong bactericidal power, and can directly kill bacteria, fungi, viruses, spores and protozoa. The sterilization speed is fast, most bacteria can be killed within 30 seconds, and 5 minutes is enough to kill individual bacteria. It is non-irritating to skin and mucous membranes and can be used for disinfection and treatment of body cavities, mucous membranes and ulcer surfaces. Non-toxic. It is not easy for microorganisms to develop drug resistance and allergic reactions. Durable use, good stability, long storage validity period. Easily soluble in water, easy to clean, and does not pollute or damage fabrics and other items.
This product is a high-efficiency gynecological sterilizing and disinfecting product. Its pH value is similar to that of the vagina and is mild. After dilution (warm boiling water) according to the instructions, it can reach 300ppm effective iodine, which is 10-20 times more than the sterilizing concentration. After flushing, it can effectively kill all kinds of iodine in the body. pathogenic microorganisms.
Povidone-iodine pharmacological effects
Povidone-iodine is an iodophor disinfectant that can directly denature and precipitate proteins in bacteria, causing the death of pathogenic microorganisms, thereby effectively disinfecting and sterilizing viruses, bacteria, spores, fungi, protozoa, etc., and has low toxicity. Povidone-iodine aqueous solution has strong pharmacological activity against Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, Treponema pallidum, hepatitis B virus, HIV, Trichomonas vaginalis, etc.
Povidone-iodine gel is a semi-fluid colloid for gynecological external use made of povidone-iodine and a hydrophilic matrix. It is a system that maintains its sustained release. Due to the continuous release of free iodine, the skin and mucous membranes maintain a certain iodine concentration, inhibiting and killing bacteria. It is mainly used for gynecological vaginal infections. It is miscible with vaginal secretions, kills pathogenic microorganisms in secretions, blocks the spread and invasion of sexually transmitted diseases, and treats other bacterial infections of vaginal diseases.
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