Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of fucoxanthin powder in China. With abundant experience, we warmly welcome you to wholesale bulk fucoxanthin powder for sale here from our factory. Quality products and reasonable price are available.
What is fucoxanthin?
Fucoxanthin powder is a natural lutein carotenoid found primarily in the chloroplasts of brown algae (such as *Fucus vesiculosus* and kelp) and single-celled microalgae (such as diatoms). Fucoxanthin absorbs blue-green light with wavelengths of 450–540 nm, giving algae their brownish-olive color. Its molecular structure contains polyene chains, epoxide bonds, hydroxyl groups, and conjugated carbonyl groups, thus exhibiting good antioxidant activity.
Fucoxanthin was first isolated in 1914 from *Fucus vesiculosus*, *Gnaphalium affine*, and kelp. Its natural sources mainly include:
Brown algae: such as kelp and *Fucus vesiculosus*, common edible algae
Diatoms: such as *Phaeodactylum tricornutum*, single-celled planktonic microalgae, which are golden-brown in color due to their high fucoxanthin content.
YTBIO supplies fucoxanthin in various dosage forms and specifications.Our fucoxanthin series products ensure chromatographic purity and batch stability. All production processes comply with international certifications such as cGMP, FSSC22000, BRC, HALAL, KOSHER, ISO9001, and ISO22000. Samples are welcome for discussion at any time.
Product Specifications:
| HPLC(Yellow oil and powder) | 1%(Powder,Oil) | 2%(Powder,Oil) | 2.5%(Oil) | 5%(Oil) | 10%(Oil) | 90%-98%(Powder) |
| UV(Yellow powder) | 5% | 10% | 20% | 30% | 50% | |
| HPLC(Green powder) | 5% | 10% | 20% | |||
| UV(Green powder) | 5% | 10% | 20% | 30% | 50% |
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Please feel free to contact us for more product specifications!
What are the effects?
Anti-oxidize effect
Fucoxanthin powder has a good antioxidant effect, even better than vitamin E and vitamin C. Fucoxanthin has protective effects against UV-B-induced damage to human fibroblasts.
Lose weight
Fucoxanthin works to eliminate fat deposits in two ways. Fucoxanthin activates a protein called UCP1, which promotes fat breakdown. It also stimulates the liver to produce DHA, which lowers cholesterol levels.
Anti-inflammatory effect
Fucoxanthin inhibits the exudation of endotoxin-induced inflammatory mediators in a dose-dependent manner, and fucoxanthin may play an important role in various inflammatory responses
Fucoxanthin is a carotenoid that is widely present in large brown algae and microalgae. In addition to its antioxidant and anti-inflammatory properties, fucoxanthin may prevent chronic diseases such as obesity, diabetes, and liver disease. Multiple studies have shown that fucoxanthin has a very protective effect on the liver. Its mechanism of action is as follows:
(1) Antioxidant: Fucoxanthin can protect liver cells from oxidative stress damage by increasing glutathione levels in liver cells and regulating the liver kinase B1-AMPKα signaling pathway.
(2) Anti-inflammation: Fucoxanthin can significantly down-regulate the expression of liver inflammatory factors and chemokines, inhibit liver inflammation and immune cell infiltration.
(3) Reduce the accumulation of triglycerides and cholesterol in the liver: Fucoxanthin can inhibit the activity of fatty acid synthesis-related enzymes, inhibit lipogenesis genes, and increase the expression of lipolytic bases and fatty acid β-oxidation-related genes, thereby inhibiting liver metabolism. Lipogenesis increases liver lipolysis; fucoxanthin can reduce the activity of metabolic enzymes related to cholesterol synthesis.
(4) Anti-liver fibrosis: Fucoxanthin can reduce the number of myofibroblasts and inhibit the activities of TIMP-1 and MMP9 by attenuating the expression of pro-fibrotic genes induced by transforming growth factor β1 and the accumulation of ROS, thus It has an inhibitory effect on liver fibrosis.
Figure 1. Metabolic degradation of fucoxanthin during gastrointestinal digestion under the action of digestive enzymes (A). Oxidation and isomerization process of fucoxanthin under lighting and heating conditions (B).
Figure 2. Fucoxanthin treats AD primarily by inhibiting Aβ aggregation, reducing oxidative stress, alleviating neuroinflammation, and modulating gut microbiota. Fucoxanthin inhibits the formation and assembly of Aβ. Second, fucoxanthin promotes the secretion of the neuronutrient BDNF and activates the Nrf2/ARE signaling pathway, AMPK/AKT signaling pathway, and PI3K/AKT signaling pathway to inhibit neuronal damage caused by oxidative stress. Besides, fucoxanthin inhibited the NF-κB pathway and reduced the secretion of COX-2 and iNOS, thereby reducing the expression of pro-inflammatory factors TNF-α and IL-1β, effectively improving neuroinflammation. Furthermore, fucoxanthin interacts with neuroinflammation by modulating gut microbiota and increasing the number of anti-inflammatory microorganisms.
Figure 3. Schematic illustration of how fucoxanthin treats PD by improving dopamine secretion and inhibiting α-syn aggregation. Fucoxanthin reduces the production of amyloid fibril aggregates and Lewy bodies by inhibiting a series of assembly processes of α-syn. On the other hand, fucoxanthin binds to dopamine receptors and exerts an agonistic effect, which is involved in the regulation of dopamine secretion and metabolism.
Figure 4. Schematic illustration of fucoxanthin for the treatment of traumatic brain injury mainly by alleviating oxidative damage, inhibiting neuronal apoptosis, and regulating autophagy. Fucoxanthin promotes the translocation of Nrf2 into the nucleus and mediates the Nrf2/ARE downstream signaling pathway to regulate the expression of SOD, HO-1, and NQO-1 and alleviate oxidative damage caused by ROS accumulation. Second, fucoxanthin effectively reduced neuronal cell death by reducing Cytc activity and inhibiting the expression of caspase-3. Fucoxanthin also regulates autophagy by upregulating the expression of Beclin-1 and LC3-II while reducing the expression of p62.
Figure 5. Schematic illustration of fucoxanthin for the treatment of depression by modulating BDNF secretion levels and improving inflammation. Fucoxanthin increases the content of BDNF and improves synaptic plasticity, thereby regulating depressive behavior. In addition, fucoxanthin attenuates neuronal damage caused by neuroinflammation and is effective in relieving depression.
Figure 6. Fucoxanthin has therapeutic effects on other neurological diseases by acting on multiple disease targets.
Figure 7. Schematic representation of a future research direction and prospective trend of fucoxanthin. Transport and metabolic mechanisms of fucoxanthin through the gut and brain (A). New targets of fucoxanthin to improve the CNS disorders (B). Construction of new brain-targeted delivery system (C). Prevention and precision dietary intervention on the delivery system of fucoxanthin in neurological disorders (D).
Direction of Application
Product applications
Pharmaceuticals
Fucoxanthin Powder exhibits diverse pharmacological activities in the pharmaceutical field. In cardiovascular health, it plays a preventative role against cardiovascular and cerebrovascular diseases. Furthermore, its antioxidant and anti-inflammatory properties offer potential for adjunctive treatment of other diseases.
Health Supplements
The application of Fucoxanthin in health supplements primarily focuses on weight management, blood sugar, and neurological aspects.
Cosmetics
Fucoxanthin in cosmetics mainly exerts dual antioxidant and anti-inflammatory effects, making it suitable for anti-aging, repair, and sensitive skin care products.
Food Industry
It can be used for food coloring, while also helping to improve food quality stability and extend shelf life.
Future Outlook
With increasing consumer focus on natural functional ingredients, the market demand for fucoxanthin is expected to continue to grow.
Product Features
Absorption and metabolism
Fucoxanthin and Amarouciaxanthin A are the main primary metabolites of fucoxanthin. Ingested fucoxanthin is hydrolyzed into fucoxanthin by digestive enzymes (such as lipase and cholesterol esterase) in the gastrointestinal tract, which then enters the systemic circulation through the lymph, and part of the fucoxanthin is degraded in the liver to Amarouciaxanthin A, a Phycoxanthin and Amarou-ciaxanthin A are then further metabolized by enzymatic reactions such as isomerization, dehydrogenation, deacetylation, oxidation and demethylation.
safety
Fucoxanthin had no effect on liver, kidney, spleen and gonadal tissue. Fucoxanthin was not teratogenic in vitro, and fucoxanthin was not teratogenic in vivo at doses of 500, 1000, and 2000 mg/kg.
stability
High-purity fucoxanthin is thermally unstable and easily oxidized. However, the fucoxanthin extract obtained from algae has stability due to the co-existence of antioxidant substances (such as polyphenols, etc.).
Fucoxanthin pigment is sensitive to light, and its stability is greatly improved when stored in the dark. At the same time, other antioxidants protect the fucoxanthin pigment from degradation. Additionally, fucoxanthin pigments are more stable at alkaline pH than neutral and acidic, with the greatest stability at pH 9 and the least stable at acidic conditions.
Fucoxanthin powder in seaweed is stable during dry processing and storage at room temperature.
If you are interested in YTBIO's fucoxanthin, please feel free to contact us via online consultation or by email. We will provide you with professional technical support and customized solutions.
Telephone：+8617782577059
Email：sales@sxytbio.com
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