What is Honokiol?
Honokiol powder is a biphenol compound and one of the main active ingredients of Magnolia officinalis. The active ingredients of Magnolia officinalis are mainly phenolic compounds (mainly magnolol and honokiol) extracted and isolated from the root bark and branch bark of Magnolia officinalis.
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Product Details Form
| Botanical Source | Magnolia officinalis Rehd. et Wils |
| Extraction site | Bark |
| MF | C18H18O2 |
| CAS | 35354-74-6 |
| Molecular weight | 266.33432 |
| Melting point | 86℃ |
| Boiling point | 400.1±40.0°C (Predicted) |
| Density | 1.107±0.06g/cm3(Predicted) |
| Storage conditions | 2-8°C |
| Acidity coefficient (pKa) | 9.89±0.48 (Predicted) |
| Solubility | insoluble in water, easily soluble in chloroform, benzene, ethanol, caustic alkali |
Benefits
1. Anti-platelet aggregation
and honokiol inhibited collagen- and arachidonic acid-induced aggregation and ATP release in rabbit platelet-rich plasma, and the aggregation of washed platelets was more significantly inhibited than that of platelet-rich plasma. The antiplatelet effects of honokiol and honokiol are due to inhibition of thromboxane bolus and intracellular Ca flux.
2. Antibacterial effect
Magnolia bark extract has strong antibacterial effect on cariogenic bacteria Streptococcus mutans, and its antibacterial active ingredient is determined to be honokiol. The minimum inhibitory concentration (MIC) of honokiol against Streptococcus mutans was 6.3 mm/day, and its antibacterial effect (on Streptococcus mutans) was stronger than that of berberine.
3. Effects on calmodulin and its dependent cyclic nucleotide phosphodiesterase activity
And Honokiol powder antagonized the stimulating effect of calmodulin (CaM) on cyclic nucleotide phosphodiesterase, IC50 was 27mmol/L. In the system without Ca2+ and CaM, it has a stimulating effect on cyclic nucleotide phosphodiesterase: and honokiol at 160 mmol/L, both reached the maximum stimulating activity, which was 2.5 times of the basic activity.
4. Has good skin care biological activity, anti-inflammatory, antibacterial, used in anti-acne and anti-inflammatory, acne prevention, oral health and other skin care and personal care products.
5. Antioxidant, 1000 times stronger than vitamin E in inhibiting lipid peroxidation, Magnolia Bark extract has the effect of scavenging free radicals.
Application direction
Daily chemical cleansing and care application with Honokiol powder
1. For chewing gum, toothpaste, mouthwash products, prevent plaque and gingivitis, prevent dental caries, and prevent bad breath;
2, used in shampoo, can stop dandruff and itching, healthy hair follicles
3. It can be used for shower gel, antibacterial, whitening and antipruritic
Cosmetic applications of honokiol
1. The antibacterial properties of honokiol can be used as cosmetic preservatives
2. Whitening water, milk, cream, cream, mask
3. Anti-acne and anti-inflammatory creams, creams, masks
4. Anti-inflammatory, broad-spectrum antibacterial, antibacterial and antiseptic, prevent acne
Recommended dosage :
Oral health care products: 0.4%
Cosmetics: 0.1%-1%
Company introduction and certificates obtained
YTBIO mainly supplies Honokiol powder etc. The company was established in 2014 and has many years of experience in R&D and production. We are committed to the R&D, production and sales of raw materials for the health industry in the 21st century. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, etc. We always maintain the highest demands on product quality.
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