Fucoidan Powder

Fucoidan powder is a natural, water-soluble sulfated heteropolysaccharide, primarily found in brown algae such as kelp, wakame, and fucus vesiculosus. It consists of L-fucose with sulfated groups as the main chain, accompanied by monosaccharide branches such as galactose, mannose, xylose, and glucuronic acid. It possesses unique biological activities: enhancing the body's immune function, exerting antioxidant effects, promoting the proliferation of beneficial bacteria, and inhibiting opportunistic pathogens.

Furthermore, studies have shown that fucoidan has an improving effect on osteoporosis. Due to its health benefits, fucoidan is widely used in functional foods, dietary supplements, marine skincare products, and biomedical materials.

YTBIO supplies fucoidan in 85% and 95% purity, offering good water solubility and strong batch stability. The product is suitable for the development of solid beverages, capsules, functional foods, and skincare products. It has complete certifications, supports sample testing and flexible MOQs. Contact us for more information.

Product Details Form

Structural composition of fucoidan

The structure of fucoidan is very complex. On the one hand, the fucoidan of different species of brown algae has different chemical compositions. In addition to the main components of fucose and sulfate, it also contains other monosaccharides (mannose, galactose, glucose, etc.) and uronic acid, some also have acetyl groups and proteins; on the other hand, the structure of fucoidan in different species of brown algae is also different, and the fucoidan obtained by different extraction methods may also have different structures, Ponce et al. Fucoidan extracted from room temperature is mainly composed of fucose, galactose and sulfate, while the fucoidan extracted at 70 °C is mainly composed of fucose and other monosaccharides (most mannose, small part of glucose, xylose, rhamnose and galactose), as well as a large amount of uronic acid and a small part of sulfate.

protective function of stomach

1.1 Fucoidan has the effect of eliminating Helicobacter pylori and can inhibit the proliferation of Helicobacter pylori and its combination with the gastric mucosa.

1.2 Fucoidan can protect the gastric mucosa and improve gastric ulcers, and has a good alleviation effect on gastric mucosal damage and chronic gastric ulcers.

Free radical scavenging, antioxidant

Environmental pollution, ultraviolet radiation and the body's own metabolism will produce a large number of free radicals. Fucoidan is a natural polymer polysaccharide mainly derived from seaweed. It is gradually becoming the focus of people's attention due to its good antioxidant activity. Studies have found that fucoidan extracted from edible Fucus algae can prevent the generation of superoxide free radicals and hydroxyl free radicals, and can also inhibit lipid peroxidation. The antioxidant properties of fucoidan are closely related to its molecular weight and sulfate group content. Currently, fucoidan with lower molecular weight can be obtained through physical, chemical and biological methods. However, there are currently many problems in chemical modification. Physical and biological modification methods may be the future development direction.

Regulate immunity

The immunity regulation of fucoidan is divided into three aspects.

For the regulation of immune organs, Fucoidan Powder can improve the immune activity of the human body by adjusting the function of the human immune system.

For the regulation of non-specific immune system, high molecular weight fucoidan can significantly restore the cytotoxicity of NK cells. After treatment with high molecular weight fucoidan, interleukin (IL)-1β, IL-2, IL-4, IL-5, IL-12, interferon (IFN)-γ, tumor necrosis factor (TNF) in the spleen )-α expression also increased significantly. In addition, fucoidan can also improve the level of cellular and molecular immune responses and regulate cytokine secretion.

Regulates specific immunity by directly inhibiting virus replication, thereby stimulating its innate immune defense and adaptive immune defense.

Reshape intestinal flora and regulate intestinal microecology

Fucoidan is a seaweed polysaccharide that has an inhibitory effect on a variety of bacteria. The antibacterial activity is related to the molecular weight of fucoidan and the content of sulfate groups and uronic acid. The lower the molecular weight, the higher the uronic acid content and the glucose content. The lower it is, the stronger its antibacterial activity is. In vitro experimental studies have found that fucoidan derived from kelp has an inhibitory effect on Escherichia coli and Staphylococcus aureus after being depolymerized into low molecular weight fucoidan.

Experimental studies have found that fucoidan can change the structure of intestinal flora, increase the diversity of bacterial flora, increase the abundance of intestinal flora, and protect the intestinal microbial barrier function.

The above studies suggest that fucoidan may be used as a potential prebiotic to regulate intestinal microecology.

Provide new ideas for improving osteoporosis

A homeostatic balance between osteoblasts and osteoclasts contributes to the healthy development of bone tissue. When this balance is disrupted, with reduced osteoblast formation and increased osteoclastic resorption, diseases such as osteoporosis can occur. Fucoidan shows promise as a bone health supplement.

Studies have found that fucoidan can inhibit osteoclastogenesis in bone marrow macrophages. It also stimulates alkaline phosphatase, mineral deposition, and bone morphogenetic protein 2 (BMP2), which are involved in bone mineralization by osteoblasts.

The above shows that fucoidan is likely to provide a good solution for improving osteoporosis.

Alleviating radiation side effects

The immune system is very sensitive to oxidative stress caused by radiation, so radiation can easily cause immune system side effects. Fucoidan can protect immune cells from the effects of radioactive radiation, alleviate DNA damage to immune cells, and reduce massive apoptosis of immune cells caused by gamma rays.

Radiation resistant

Experimental verification: U937 cells were irradiated with 8Gy, and the survival rate of cells in the fucoidan-containing medium was significantly improved; the survival period of mice taking fucoidan before irradiation with 8Gy was prolonged and the survival rate was improved.

Mechanism of action

● Inhibit the proliferation of Helicobacter pylori

Fucoidan can effectively inhibit the attachment of Helicobacter pylori to human gastric epithelial cells, thereby inhibiting its proliferation.

● Prevent the adhesion and invasion of Helicobacter pylori

Fucoidan contains sulfate groups, which can bind to Helicobacter pylori and prevent it from adhering to gastric epithelial cells; at the same time, fucoidan inhibits its production of urease and protects the acidic environment of the stomach.

● Antioxidant effect, reducing toxin production

Fucoidan is a good antioxidant that can quickly scavenge oxygen free radicals and reduce the production of harmful toxins chloramine.

● Anti-inflammatory effect

Fucoidan powder can inhibit the activities of lectins, complement and heparanase, and reduce inflammatory reactions.

Fucoidan powder is a high-quality dietary fiber that has important physiological functions such as promoting gastrointestinal motility. It can adsorb toxic substances and accelerate their excretion, especially adsorbing various toxic heavy metals such as Pb, Sn, and Cd, and reduce the impact of these substances on the human body. Poison. Based on its multiple functional activities, fucoidan has been widely used in functional foods and beverages, and its application forms mainly include tablets, capsules, granules, etc. There are already many mature products used in the functional food field to exert their health effects such as anti-Helicobacter pylori, improving immunity, and improving the gastrointestinal tract.

Interested in YTBIO's fucoidan powder? Feel free to contact us via online consultation or email. We will provide you with professional technical support and customized solutions.

Telephone +8617782577059

Email sales@sxytbio.com

Hot Tags: fucoidan powder, China fucoidan powder manufacturers, suppliers, factory