Description
Spermidine trihydrochloride is a natural polyamine synthesized by spermidine synthase from putrescine and dcSAM. It is a new type of autophagy inducer that negatively regulates N-methyl-d-aspartate (NMDA).
Spermidine is a polyamine found in the body that induces the anti-aging process of autophagy. Spermidine levels naturally decline as we age, but can be replenished by including spermidine-rich foods in your diet or taking supplements. Although this type of supplement has been around relatively recently, spermidine has quickly become famous for its health and longevity benefits.
Spermidine occurs naturally in the human body and is also found in wheat germ and is a typical component of the Mediterranean diet, which to some extent hints at spermidine's longevity benefits. This substance, designed to improve health and extend lifespan, does not simply provide nutrients but works on different pathways in the body to slow down the aging process. Research has confirmed that the most direct mechanism by which spermidine benefits the body is the induction of autophagy.
In studies in recent years, researchers have demonstrated that spermidine also acts as a caloric restriction mimetic, inducing the body into a fasted state and inducing autophagy. Cell renewal has many anti-aging benefits. During the process of autophagy, cells reuse damaged organelles to rejuvenate, regulate cell metabolism, and balance available nutrients for survival.
The health and longevity benefits of caloric restriction through fasting are well known, but few people are able to adhere to sustained fasting. Using caloric restriction mimetics like spermidine supplements can achieve the same health benefits, such as preventing inflammation and oxidation. It can reduce stress and at the same time avoid uncomfortable reactions such as prolonged hunger. It is extremely friendly to most people, including the elderly.
English name: Spermidine trihydrochloride
CAS number: 334-50-9
Molecular weight: 254.629
Density: 0.906 g/cm3
Boiling point: 246.6ºC at 760 mmHg
Molecular formula: C7H22Cl3N3
Melting point: 257-259 °C(lit.)
The role and efficacy of spermidine
1. Delay aging
Spermidine has a very good anti-aging effect. Spermidine can promote cell autophagy, promote the recovery of cell components, effectively help the body remove dead cells and toxic cells, and delay the aging of the body. Spermidine also has good anti-aging effects. Its antioxidant properties can scavenge free radicals in the body, avoid cell damage, and delay aging. It is especially suitable for people who want to stay young forever.
2. Prevention of senile dementia
Spermidine will participate in various cell processes in the body, such as gene transcription, translation, cell proliferation and cell survival that we are familiar with. It also has a good effect on the stability of genomic DNA. Supplementing spermidine can effectively promote cell activity. , effectively prevents the occurrence of Alzheimer's disease, and is very suitable for middle-aged and elderly people.
3. Protect nerves
Spermidine has a very good protective effect on neuronal damage caused by inflammation, oxidative stress and ischemia. Spermidine can effectively protect nerves, protect neuronal damage, prevent the deterioration of damaged nerves, and accelerate damaged nerves. growth, repair damaged nerves, protect nerves and promote good health.
Physiological Function
• Spermidine is a polyamine that can be found in all living organisms and is fundamental for the regeneration of tissues, cell proliferation, and the growth of cells.
• When taken orally, It is involved in multiple cellular processes such as gene transcription, translation, maintenance of genomic DNA stability, cell proliferation, and cell survival. Spermidine plays a key role in the mechanisms of the molecules and cells engaged with the modulation of the immune system, stem cell functions, neuro aging, aging, cardioprotection.
Structure/Function Claims
• Promote metabolism, regulate immune system
• Improve cognition and neuroprotection
• Providing protection against cancer
• Improving cardiovascular health
Formulating Techniques
• It can be used as an ingredient in dietary supplement ingredient.
Stability
• Keep sealed, dry and away from light, storage at 2℃ to 8℃.
• Raw powder is stable for at least 2 years when stored in tight container and keep dry and away from light at 2℃ to 8℃.
Uses
• Spermidine is recommended for use as a dietary supplement ingredient.
Spermidine:
Spermidine is a polyamine that can be found in all living organisms and is fundamental for the regeneration of tissues, cell proliferation, and the growth of cells. It is involved in multiple cellular processes such as gene transcription, translation, maintenance of genomic DNA stability, cell proliferation, and cell survival. Critically, homeostatic imbalance, which causes cellular malfunction
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