Palmitoyl hexapeptide-12 is composed of six amino acids, glutamic acid, tyrosine, arginine, and histidine. Palmitoyl hexapeptide-12, a signal peptide belonging to the Matrikine family, is particularly relevant for repairing age-related skin damage. The hexapeptide VGVAPG fragment is repeated as many as six times throughout the molecular structure of elastin, hence the name "spring fragment".
Elastin is an important component of skin composition. Elastin only contains 5% in the skin, but it is the key to stimulate the production of collagen and elastic fibers in the skin. Collagen, which accounts for 70% of the skin, determines the softness and fullness of the skin. Firm and elastic, and 90% of elastic fibers are composed of elastin. Therefore, elastin is the youth of the skin.
Collagen contains a hydrophilic natural moisturizing factor, which has a moisturizing effect. Moreover, the triple helix structure can strongly lock in moisture, keeping the skin moist and supple at all times. When collagen is absorbed by the skin, it is filled between the dermis of the skin to increase the tightness of the skin, generate skin tension, shrink pores, and make the skin tight and elastic.
It can be seen that promoting the production of elastin and collagen is the key to anti-wrinkle and anti-aging.
Lipopeptide/palmitoyl hexapeptide/palmitoyl hexapeptide-12 has similar properties that can inhibit neurotransmitters, block the conduction function between neuromuscles, avoid excessive muscle contraction, prevent the formation of fine lines, and slow down the strength of muscle contractions. Relax muscles, reduce the occurrence of dynamic lines and eliminate fine lines; effectively reorganize collagen elasticity, increase the activity of elastin, relax facial lines, smooth wrinkles and improve relaxation. Can be used in cosmetics as an anti-wrinkle ingredient with excellent results.
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