Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of undenatured collagen type ii in China. With abundant experience, we warmly welcome you to wholesale bulk undenatured collagen type ii for sale here from our factory. Quality products and reasonable price are available.

Product Description

Undenatured Collagen Type II, also known as UC - II, is a kind of using low temperature extraction technology patent, extracted from animal cartilage, retained complete three spiral structure and biological activity of Type II Collagen. UC-II is the type II collagen that is most similar to human articular cartilage in nature. Many studies at home and abroad have proved that UC-II plays a very important role in eliminating joint inflammation, improving joint pain and other symptoms.

Undenatured Collagen Type II in animal cartilage as raw material, adopting low temperature extraction technology, the full retention of macromolecular Collagen was no change in three spiral Collagen products, the molecular weight at about 300000 Da. It can reduce the symptoms of joint swelling and pain, repair damaged joints, inhibit inflammation, improve rest pain, morning stiffness, tender joint index, swelling joint index. Collagen Type II was widely found in animal cartilage tissues and closely bound to proteoglycans, with a significantly better effect than ammonose and chondroitin sulfate.

Product Details Form

The difference between ammonose/chondroitin /UC-II
Nutrients	Glucosamine	Chondroitin	UC-II
Source	Shell extraction from Marine crustaceans	Sharks or cattle	Chicken breast cartilage/animal cartilage
Function	Lubrication/nutrition	It keeps water in the cartilage	Blocking inflammation promotes cartilage regeneration
Principle	It is the precursor of proteoglycan synthesis in cartilage matrix and one of the nutrients required by cartilage.	It absorbs and retains water as it enters the joint, thickening the cartilage.	Oral immune tolerance. Reacts with intestinal lymphoid tissue, turns off the immune response against articular cartilage, and stimulates cartilage repair by cell growth factors.
Recommended daily dosage	1500 mg/day	1200 mg/day	40 mg/day

What are the functions?

Many studies at home and abroad have shown that supplementation of 40 mg of UC-II per day can achieve the following effects:

1. immune regulation, eliminate inflammation, relieve pain.

2. Improve the internal environment of the joint and delay the degradation/loss/wear of cartilage matrix.

3. Promote the repair and regeneration of articular cartilage.

4. Improve the structure of articular cartilage and enhance the toughness of cartilage.

5. increase joint synovial fluid, improve joint flexibility.

6. Improve the symptoms of osteoarthritis and rheumatoid arthritis.

7. promote the long-term health of joints.

How does it work?

General joint care products, such as ammonia sugar, chondroitin, collagen, etc., are designed to improve joint function by supplementing the nutrients needed by cartilage. The mechanism of UC-II improving joint function is "oral immune tolerance". Oral immune tolerance refers to the oral administration of a certain protein antigen that leads to specific immunity in local gut associated lymphoid tissues, thereby inhibiting the systemic immune response.

The collagen in articular cartilage is 80 to 90 percent type II collagen. The cause of joint inflammation is immune disorder. The immune system considers collagen type 2 protein in cartilage as an invading "enemy" and sends immune cells to attack the cartilage, resulting in joint inflammation and cartilage damage. It's like our allergy, where our immune system becomes intolerant to collagen type 2. To block inflammation, the first step is to get the immune system to stop seeing collagen type 2 in articular cartilage as the enemy. This process is to establish immune tolerance.

When we take UC-II orally, UC-II acts as an antigen and reacts with Pyle's collecting lymph nodes in the intestine. After contact with UC-II antigen, naive T cells in the lymph nodes transform into T regulatory cells that recognize collagen type II and know that collagen type II is "our own". These T-regulatory cells arrive at the articular cartilage and transmit the message that collagen type 2 is "inside" to the immune cells that are still attacking the articular cartilage. Instead of secreting inflammatory factors to attack the articular cartilage, these immune cells start secreting anti-inflammatory factors to block the inflammation of the joint. At the same time, T regulatory cells also secrete cell growth factors to activate the ability of chondrocytes to synthesize cartilage matrix and promote cartilage repair.

UC-II works directly with the immune system to block inflammation and prevent cartilage degradation; On the one hand, it promotes the synthesis of cartilage matrix and cartilage repair. Finally, the health of cartilage can be improved. Therefore, UC-II is also called "revolutionary material for joint protection".

Company introduction and certificates obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

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