Spermidine Trihydrochloride

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of spermidine trihydrochloride in China. With abundant experience, we warmly welcome you to wholesale bulk spermidine trihydrochloride for sale here from our factory. Quality products and reasonable price are available.

Spermidine trihydrochloride is a natural polyamine synthesized by spermidine synthase from putrescine and dcSAM. It is a new type of autophagy inducer that negatively regulates N-methyl-d-aspartate (NMDA).

Spermidine trihydrochloride is a polyamine. Spermidine is a naturally occurring substance in human cells. However, as age increases, the content of spermidine in human cells will decrease sharply, and the autophagy function of cells will gradually weaken. The loss of autophagy function will further cause the body to aging, thus forming a vicious cycle. Therefore, it is particularly important to supplement spermidine

An aliphatic polyamine compound that is present in ribosomes and living tissues and is isolated from human semen. It has excellent effects in anti-inflammatory, antioxidant, enhancing mitochondrial metabolic function, and improving protein homeostasis, and can actively fight against a variety of age-related diseases, such as cardiovascular disease, neurodegeneration, etc.

It supports sample testing and third-party testing. It has its own factory and many years of production experience. It has advanced equipment and can guarantee product quality and delivery. You can visit the factory. There are good after-sales service and very preferential prices, and there will be different discounts according to different order quantities.

YTBIO supplies Spermidine (334-50-9) as well as wholesale Spermidine trihydrochloride, Spermidine 3HCL 99%, Spermidine 99%, Wheat Germ Extract 1% Spermidine
YTBIO has ten years of industry experience and has long been focused on providing high-quality products. All of our products have been inspected to ensure that we provide customers with high-quality products. During the cooperation process, we have a professional business team to connect with you, and we support factory inspections to ensure the professionalism of our cooperation.

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Anti aging 

Scientists have found that spermidine can effectively repair damaged cells. The aging of cells determines the degree of aging of the human body. Autophagy is the ecosystem of young cells and the core mechanism for removing aging cells. Spermidine also has good antioxidant properties and can scavenge free radicals in the body to avoid cell damage.

Build muscle mass

Spermidine can build the body's muscle mass, increase muscle oxygen content and endurance, and reduce muscle soreness and fatigue. Research shows that spermidine can increase muscle alanine content in muscles, thereby increasing oxygen content in muscles and delaying the onset of muscle fatigue.

Balance blood sugar

It can promote the synthesis and secretion of insulin, improve blood sugar utilization, help control blood sugar levels, and reduce the symptoms of diabetes.

Promote body growth and development

Spermidine is one of the necessary components for the production of protein in the body and can promote the growth and development of the body, especially for teenagers and children.

Improve immunity

Spermidine can stimulate the body to produce lymphocytes and antibodies, increasing the body's immunity. In addition, spermidine also helps promote human tissue repair and metabolism, and can help eliminate free radicals and resist aging.

Promote gut health

Spermidine is a nutrient for beneficial bacteria in the intestines. It can promote the reproduction and growth of beneficial bacteria in the intestines, maintain the balance of intestinal flora, and promote intestinal health.

Regulate and protect nerves

Spermidine has antioxidant and anti-inflammatory effects on neurodegeneration, can improve learning and memory, protect nerve cells, and prevent Alzheimer's disease.

Spermidine may prevent age-related memory decline, according to a collaborative study by scientists in Germany and Austria. On September 1, 2013, the results were published in the online version of Nature Neuroscience.

Protect cardiovascular

In 2016, research published in Atherosclerosis confirmed that spermidine can reduce lipid accumulation in atherosclerotic plaques. In the same year, "Nature Medicine" published a study confirming that it can reduce cardiac hypertrophy and improve diastolic function, thereby protecting the heart and extending the lifespan of mice.

Researchers have also confirmed in humans that dietary intake of spermidine can improve blood pressure and reduce cardiovascular disease morbidity and mortality.

Improve Alzheimer's disease

Spermidine intake is beneficial to human memory function. The team of Professor Reinhart from Australia found that spermidine treatment can improve the cognitive function of the elderly. The study adopted a multi-center double-blind design and enrolled 85 elderly people in 6 nursing homes, who were randomly divided into two groups and used different doses of spermidine. Their cognitive function was evaluated through memory tests and divided into four groups: no dementia, mild dementia, moderate dementia and severe dementia. Blood samples were collected to evaluate the concentration of spermidine in their blood. The results showed that spermidine concentration was significantly related to cognitive function in the non-dementia group, and the cognitive level of elderly people with mild to moderate dementia improved significantly after ingesting high doses of spermidine.

Improve metabolic diseases

A 2014 study in The European Journal of Pathology showed that spermidine supplementation improved glucose utilization and significantly reduced body weight in obese mice.

In 2017, research published in the sub-journal "Cell Death & Disease" of "Nature" showed that spermidine can reduce the weight gain caused by high-calorie diet in mice and improve obesity-related symptoms.

In the pharmaceutical field, spermidine hydrochloride is used as a hepatoprotective drug that can improve liver function and reduce liver damage. In addition, spermidine hydrochloride can be used to treat conditions such as high cholesterol, hypertriglyceridemia, and cardiovascular disease. Spermidine hydrochloride works by reducing plasma homocysteine (Hcy) levels, thereby reducing the risk of cardiovascular disease. Studies have shown that spermidine hydrochloride can promote the metabolism of Hcy and reduce the risk of cardiovascular disease by reducing plasma Hcy levels. A study on the effects of spermidine hydrochloride on cardiovascular disease risk showed that spermidine hydrochloride can reduce plasma Hcy levels, thereby reducing the risk of cardiovascular disease. In the study, researchers divided participants into two groups, with one receiving spermidine hydrochloride supplementation and the other receiving a placebo. Study results showed that participants who received spermidine hydrochloride supplementation had significantly lower plasma Hcy levels and a corresponding reduction in cardiovascular disease risk. Additionally, there are other studies supporting spermidine hydrochloride's role in reducing the risk of cardiovascular disease.

In the food field, spermidine hydrochloride is used as a flavor enhancer and humectant to enhance the taste of food and maintain the moisture of food. In addition, spermidine hydrochloride can also be used as a feed additive to improve the growth rate and muscle quality of animals.

In cosmetics, spermidine hydrochloride is used as a humectant and antioxidant to maintain skin moisture and reduce free radical damage. In addition, spermidine hydrochloride can also be used in sunscreens to reduce the damage of ultraviolet rays to the skin.

In the agricultural field, spermidine hydrochloride is used as a plant growth regulator to promote crop growth and increase yields.

Activate autophagy and delay aging mechanism

By inducing autophagy and promoting the recovery of cellular components, spermidine can fight aging and extend lifespan.

In 2009, a study published in Nature Cell Biology found that spermidine extended the lifespan of yeast, flies, worms, and human immune cells. And a significant increase in autophagy activity stimulated by spermidine was observed.

The researchers found that in aged yeast, spermidine triggers epigenetic deacetylation of histone H3 by suppressing oxidative stress and necrosis by inhibiting histone acetyltransferase (HAT). (To put it simply, it is known that the aging process is accompanied by changes in the acetylation modification of numerous genes and proteins)

In contrast, depletion of endogenous polyamines leads to hyperacetylation, massive production of reactive oxygen species, early necrotic cell death, and shortened lifespan.

Changes in chromatin acetylation status lead to significant upregulation of various autophagy-related transcripts, thereby triggering autophagy in yeast, Drosophila, worms, and human cells.

Separately, a 2009 study compared spermidine to resveratrol (also thought to have some potential longevity effects) and found that spermidine inhibited general histone acetylase activity in vitro. , induce cell autophagy and delay aging.

Moreover, researchers found that these two ingredients effectively promoted the autophagy of more than 170 different proteins, thereby appropriately delaying aging.

And putative modes of action of resveratrol and spermidine as autophagy inducers were proposed.

Resveratrol activates the deacetylase activity of Sirtuin1 protein, thereby inhibiting the transcriptional activity of several transcription factors involved in aging and inflammation, thereby extending lifespan.

Spermidine achieves anti-aging effects by inhibiting the general histone acetylase activity of yeast and mouse liver extracts.

Moreover, the results of experimental studies clearly indicate that activation of autophagy is primarily responsible for the anti-aging effects of rapamycin, resveratrol, and spermidine.

In addition, spermidine can also delay aging by delaying the degeneration of nerve cells.

Studies have found that spermidine has a neuroprotective effect on neuronal damage caused by inflammation, oxidative stress and ischemia.

Through autophagy-dependent and autophagy-independent pathways, spermidine counteracts oxidative-induced neuronal damage, thereby slowing down the aging process and promoting growth in species including yeast, Drosophila, worms, mice, and humans. internal stress resistance.

This helps prevent age-related neurodegenerative diseases, such as Parkinson's disease, etc., and delays aging.

When I think of activating autophagy to fight aging, I think of fasting, which many people may not be able to do.

However, spermidine can achieve this effect. If you want to fight aging and extend your life, it is important to activate autophagy. There are two Nobel Prizes behind this.

In the 1960s, Belgian scientist Christian de Duve discovered autophagy, coined the term autophagy, and eventually won the Nobel Prize in Medicine.

On October 3, 2016, Japanese scientist Yoshinori Ohsumi once again won the Nobel Prize in this field.

He is the researcher who has made the greatest contribution since the introduction of the autophagy theory. His research has enlightened many scholars.

Autophagy basically allows the body to remove aging cells in a timely manner, produce new cells, and promote repair.

In daily life, regular fasting is beneficial to cell autophagy. If you are unable to fast, you can try supplementing spermidine.

Older people with severe memory loss can also try it, because spermidine can improve memory and slow down cognitive decline. It is also effective in improving Alzheimer's disease because it can trigger the dissolution of amyloid-β plaques.

Our aim is to establish long-term cooperative relations with customers, so we focus on after-sales service and product quality. So far, our products have been exported to various countries and are well received by customers. Our price has an absolute advantage among the peers, and we will have different discounts according to the order quantity.

Why choose us?

Quality Products and Service: We are committed to providing quality products and excellent service. Our products undergo strict quality control and safety testing to ensure product purity and nutritional value. We have a professional team for product development and production to ensure that every product meets the highest standards.

Rich experience and expertise: We have rich experience and expertise, accumulated many years of experience in the field of plant extracts and health. We research and understand the world of healthy ingredients in depth.

Traceable supply chain: We fully manage and trace the supply chain of products to ensure the reliability of the source of products and the production environment.

Environmental protection and sustainable development: We attach importance to environmental protection and sustainable development. We take environmentally friendly measures to reduce our impact on the ecosystem.

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

1KG/Aluminium bags , 25kg/barrel

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We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation

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