Product Description
Tyrosinase has a β-sheet at both its N-terminus and C-terminus, and several α-helices between the N-terminus and C-terminus. This structure facilitates the formation of the active site of tyrosinase. Tyrosinase is widely distributed in microorganisms, animals, plants, and humans. In plants, tyrosinase is generally called polyphenol oxidase; in insects, it is generally called phenol oxidase; and in microorganisms and humans, it is called tyrosinase. Tyrosinase is a key enzyme in the synthesis of melanin in organisms and in the browning of fruits and vegetables. It plays an important role in the tanning process during insect molting and in wound healing. Bacterial melanin can protect bacterial cells and spores from ultraviolet radiation damage. Tyrosinase has dual catalytic functions as a monophenolase and a diphenolase. Under the action of monophenolase, tyrosine is hydroxylated to L-DOPA. Under the action of diphenolase, LDOPA is oxidized to dopaquinone, and dopaquinone then undergoes a series of reactions to produce melanin. Abnormal tyrosinase activity can lead to melanoma and early-onset Alzheimer's disease. Pigmentation caused by abnormal melanin production is a significant indicator of aging in animals and browning in fruits and vegetables. Tyrosinase inhibitors have a wide range of applications, including beauty and health care, treatment of pigmentary skin diseases, pest and disease control, and food preservation.
What are the benefits?
Tyrosinase is an important biological enzyme that plays a variety of roles and functions in the human body, mainly including the following:
1. Promoting melanin synthesis
Tyrosinase is a key enzyme in melanin synthesis. It catalyzes the conversion of tyrosine to dopa, which is then further oxidized to dopaquinone, ultimately forming melanin. This process determines the pigmentation of the skin, hair, and eyes, affecting an individual's skin color, hair color, and iris color.
2. Protecting the skin from UV damage
Melanin has the ability to absorb and scatter ultraviolet (UV) radiation. Tyrosinase promotes melanin production, helping the skin form a natural barrier, reducing UV damage to skin cells, and lowering the risk of sunburn, photoaging, and skin cancer.
3. Participating in neurotransmitter synthesis
In the nervous system, tyrosinase participates in the synthesis of neurotransmitters such as dopamine, having some influence on nerve signal transmission, mood regulation, and cognitive function, although this role is relatively minor.
4. Antioxidant effects
Some studies suggest that tyrosinase may have some antioxidant capacity, helping to scavenge free radicals and reduce cellular oxidative damage, but the specific significance of this effect in the human body requires further research.
Application directions
Tyrosinase, an important oxidase, has wide applications in multiple fields. The following are its main application areas:
1. Cosmetics and Daily Chemicals
- Whitening Product Development: By inhibiting tyrosinase activity, melanin production is reduced, resulting in whitening creams, serums, and other products. Ingredients such as arbutin and kojic acid are often used as tyrosinase inhibitors.
- Bio-hair Dyeing: Utilizing tyrosinase to catalyze the conversion of tyrosine into melanin, mild and environmentally friendly hair dyeing technologies are achieved. For example, tyrosinase-based bio-hair dyeing systems can prepare semi-permanent hair dyes.
2. Pharmaceuticals and Biomedicine
- Dermatology Treatment: In the treatment of diseases such as vitiligo and hyperpigmentation, targeted therapy strategies are developed by regulating tyrosinase activity or utilizing its catalytic properties. For example, tyrosinase can be used to catalyze the in-situ generation of therapeutic drugs.
- Drug Synthesis: Used to synthesize drugs such as levodopa (L-DOPA) and to generate procancer drugs through bioorthogonal reactions, overcoming drug resistance problems.
3. Food Industry
- Improving Food Color: Participates in the oxidation of phenolic substances during food processing, improving the color and flavor of products such as tea, coffee, and chocolate.
- Food Additives: Utilizes its cross-linking properties as a food additive to improve food texture and stability.
4. Biomaterials and Tissue Engineering
- Biomaterial Modification: Modifies biomaterials such as silk fibroin and mussel protein with dopa to enhance their antioxidant properties, adhesion, and biocompatibility, for use in tissue engineering scaffolds, bioadhesives, etc.
- Biosensor Development: Based on the specific catalysis of tyrosinase on substrates such as phenols and catecholamines, develops biosensors for detecting environmental pollutants and biomarkers.
5. Environmental Engineering
- Wastewater Treatment: Efficiently oxidizes phenolic pollutants, converting them into insoluble polymers for wastewater treatment in industries such as dyeing and printing, and chemical processing.
Company introduction and certificates obtained
Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
Our packaging
1KG/Aluminium bags , 25kg/barrel
Storage: Store in a cool, dry, clean place away from moisture and direct light.
We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation
Our team
We have a professional R&D team and sales team, which not only ensure product quality, but also ensure a good cooperation experience for customers in the pre-sale, in-sale and after-sale processes. Our sales team has been trained in professional product knowledge, and can respond and solve every problem in cooperation in a timely manner
The payment methods we support are: T/T, VISA, XTransfer, Master Card, Western Union, Alibaba Payment, e-Checking, Online Bank Payment
We support shipping by sea, air, DHL, FedEx, TNT, UPS, EMS, SF
Hot Tags: tyrosinase, China tyrosinase manufacturers, suppliers, factory
