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Alpha Lipoic Acid

Alpha Lipoic Acid

CAS No.: 1077-28-7
Molecular Formula: C8H14O2S2
Molecular Weight: 206.33
EINECS No.: 214-071-2
Shipping Speed:1-3 days
Inventory:In stock
Certificates:cGMP, FSSC22000, HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA, etc.
MOQ:25 kg
Sales group:not for individual customers
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Product Introduction

Product Description

 

Lipoic acid is an organic compound with important physiological functions. It acts as a key coenzyme in the body's metabolic processes and possesses potent biological activity in scavenging free radicals and delaying oxidative damage, making it a vitamin-like substance with both metabolic and defensive functions. After being absorbed through the intestines, it can enter various tissue cells and exhibits both fat-soluble and water-soluble properties, allowing it to function in different physiological environments throughout the body. Its bioavailability and tissue distribution are superior to most single-soluble antioxidants.

In energy metabolism pathways, lipoic acid participates as a coenzyme in two core oxidative decarboxylation reactions: the metabolic processes catalyzed by the pyruvate dehydrogenase complex and the α-ketoglutarate dehydrogenase complex, primarily undertaking the core function of acyl transfer. Its specific mechanism of action is as follows: lipoic acid can bind to the acyl group and the acetyl group on the pyruvate molecule to form a stable thioester bond, subsequently transferring the acetyl group to the sulfur atom site of coenzyme A, completing the transfer of metabolic intermediates. The dihydrolipoamide produced in the reaction can be re-oxidized with the participation of dihydrolipoamide dehydrogenase and NAD⁺, restoring the oxidized lipoamide structure and achieving a catalytic cycle. This process is a crucial step in the breakdown of carbohydrates for energy and the normal operation of the tricarboxylic acid cycle.

From a molecular structure perspective, α-lipoic acid possesses a disulfide five-membered ring structure with high electron density and strong electrophilicity, allowing it to react directly with various free radicals, thus exhibiting highly efficient antioxidant activity. Simultaneously, the sulfhydryl groups in its molecule readily undergo redox reactions, protecting sulfhydryl enzymes in the body from damage by heavy metal ions and enhancing the body's detoxification capacity. Based on these mechanisms, lipoic acid has clear health benefits and medicinal value in areas such as combating fatty liver, lowering plasma cholesterol, reducing oxidative stress, and delaying aging.

 

What are the benefits?

 

Alpha-lipoic acid (ALA) has long been used to promote health. It has been shown to promote antioxidant protection, detoxification and liver health, support blood sugar control and healthy nerve function, enhance metabolism, aid in detoxification, and prevent aging.

1. Relieving Diabetes Symptoms

7. Alpha-lipoic acid can enhance β-cell function and peripheral tissue insulin sensitivity in patients with type 2 diabetes, improving insulin resistance. Furthermore, ALA's unique antioxidant properties can maintain the body at high antioxidant levels, improving nerve conduction speed, restoring nerve energy pathways, and having a significant effect on diabetic-induced neuropathy.

2. Supporting Anti-Glycation

Alpha-lipoic acid has a dual protective effect against glycation, stabilizing blood sugar and preventing sugar from binding to collagen, making it a key development direction for anti-glycation beauty products. Simultaneously, ALA's activation of vitamin C can compensate for levels reduced due to UV protection, enhancing the skin's ability to resist external stimuli.

3. Skin Nourishment and Anti-aging

Alpha-lipoic acid (ALA) possesses remarkable antioxidant capabilities, effectively removing reactive oxygen species that cause skin aging. Because its molecules are smaller than vitamin E and it is both water-soluble and fat-soluble, it is easily absorbed by the skin.

4. Liver Protection

Alpha-lipoic acid is a chelating agent for many metals. Working synergistically with dihydroalpha-lipoic acid (DAL), it can chelate metal ions such as cadmium, nickel, copper, lead, and ferric ions, reducing the toxicity of these metals to the liver. Therefore, it was initially used as an antidote for food poisoning or metal poisoning.

5. Reducing Obesity

Alpha-lipoic acid supplements can significantly reduce body fat levels, especially noticeable in women and overweight individuals.

 

Application directions

 

Alpha-lipoic acid (ALA) has wide applications in various fields due to its unique antioxidant, anti-inflammatory, and metabolic regulation properties. The main application areas are as follows:

Health Supplements

  • Antioxidant Supplements: As a dietary supplement, it helps eliminate free radicals in the body, enhances the body's antioxidant capacity, and delays aging. It is often used in synergy with other antioxidants (such as vitamin C, vitamin E, and glutathione).
  • Metabolic Regulation Products: Used to regulate glucose and lipid metabolism, assist in weight control, and improve symptoms related to metabolic syndrome, such as insulin resistance and dyslipidemia.

Cosmetics

  • Anti-aging Skincare: Added to skincare products such as lotions, serums, and eye creams, it reduces oxidative damage to the skin through antioxidant effects, delays skin aging, and improves skin elasticity, radiance, and texture.
  • Skin Repair and Care: Helps repair the skin barrier function, reduces inflammation, and has a soothing and therapeutic effect on sensitive skin and acne-prone skin.

Assisted Reproduction Field

  • Gamete and Embryo Protection: Added to sperm processing or embryo culture media during in vitro fertilization (IVF) to protect sperm and embryos from oxidative stress damage, improving fertilization rate, embryo quality, and pregnancy success rate.
  • Adjunctive Treatment for PCOS Patients: Used in combination with inositol and other supplements to improve insulin sensitivity and endocrine metabolic disorders in patients with polycystic ovary syndrome (PCOS), increasing the number of retrieved oocytes and the rate of high-quality embryos.

Sports Nutrition Field

  • Sports Recovery and Performance Enhancement: Helps athletes recover quickly after strenuous exercise, reduces muscle fatigue and inflammation, and improves athletic performance and endurance. Often used in conjunction with other sports nutrition supplements (such as creatine and protein).

 

Company introduction and certificates obtained

 

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

 

Certificates

Our packaging

 

1KG/Aluminium bags , 25kg/barrel

Storage: Store in a cool, dry, clean place away from moisture and direct light.

We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation

Packing & shipping

Our team

 

We have a professional R&D team and sales team, which not only ensure product quality, but also ensure a good cooperation experience for customers in the pre-sale, in-sale and after-sale processes. Our sales team has been trained in professional product knowledge, and can respond and solve every problem in cooperation in a timely manner

Team

Factory

The payment methods we support are: T/T, VISA, XTransfer, Master Card, Western Union, Alibaba Payment, e-Checking, Online Bank Payment

We support shipping by sea, air, DHL, FedEx, TNT, UPS, EMS, SF

Payment&Shipping

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