Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of papain in China. With abundant experience, we warmly welcome you to wholesale bulk papain for sale here from our factory. Quality products and reasonable price are available.
Product Description
Papain is a sulfhydryl (-SH) endopeptidase containing both protease and esterase activities. It exhibits broad specificity and strong hydrolytic ability against animal and plant proteins, polypeptides, esters, and amides. It also possesses synthetic capabilities, synthesizing protein hydrolysates into protein-like compounds. It is soluble in water and glycerol, with aqueous solutions being colorless or pale yellow, sometimes milky white; it is almost insoluble in organic solvents such as ethanol, chloroform, and ether. It is most effective at pH 5.7 (generally 3–9.5 is acceptable), but also functions in neutral or slightly acidic conditions, with an isoelectric point of 18.75. Its optimal temperature is 55–60℃ (generally 10–85℃ is acceptable), and it is highly heat-resistant, not completely inactivated even at 90℃. It is inhibited by oxidizing agents and activated by reducing agents. Enzyme dried without clarification is considered crude enzyme.
What are the benefits?
Papain is a natural plant protease extracted from papaya, possessing various effects and benefits. Its main applications and effects are as follows:
1. Promotes Digestion
- It breaks down proteins in food into smaller peptides and amino acids, reducing the digestive burden on the stomach and intestines, and relieving indigestion symptoms such as bloating and belching. It is often added to digestive enzyme preparations and is suitable for people with weak gastrointestinal function or those who have consumed high-protein foods.
2. Anti-inflammatory and Swelling Reduction:
- By degrading inflammatory mediators and fibrin, it reduces tissue edema, relieving pain and swelling caused by inflammation such as sprains, contusions, and rheumatoid arthritis. It is often used as an adjunct treatment, but should be used with caution on open wounds.
3. Promotes Wound Healing
- It can remove necrotic tissue and blood clots, promote the growth of new granulation tissue, and accelerate the healing of wounds such as chronic ulcers and burns. It is often used in conjunction with disinfectants and is suitable for difficult-to-heal wounds, but should be used under the guidance of a doctor.
4. Beauty and Skin Care
- Whitening and Spot Reduction: Inhibits tyrosinase activity, reduces melanin production, breaks down skin pigmentation, and helps fade age spots and freckles.
- Exfoliation: Gently breaks down the aged stratum corneum, promotes keratin metabolism, and makes skin smoother and more delicate. Suitable for sensitive skin, avoiding the irritation of traditional acid exfoliants.
- Moisturizing: Hydrolyzed products form an amino acid derivative film on the skin surface, enhancing the skin's moisturizing ability.
5. Food Processing
- Meat Tenderizing: Breaks down collagen and elastin in meat, disrupting the muscle fiber network, making the meat tender. Commonly used in making tenderizing powder, processing offal, tripe, etc.
- Seafood Skinning: Helps remove the outer skin of sea cucumbers, squid, and other seafood, improving processing efficiency and reducing nutrient loss.
- Beer Quality Improvement: Hydrolyzes proteins in beer, reducing turbidity and improving taste and stability.
Application directions
Papain, a broad-spectrum plant protease, has wide applications in multiple fields due to its unique enzymatic hydrolytic properties. The following are its main application areas:
1. Food Industry
- Meat Tenderizing: Breaks down collagen and muscle fibers in meat, making it tender, smooth, and crisp. Commonly used in the processing of offal, tripe, and beef products, it replaces traditional high-pressure cooking or caustic soda treatment, reducing costs while retaining nutrients.
- Beer Clarification: Hydrolyzes the complexes formed by proteins and polyphenols in beer, improving solubility, preventing turbidity during refrigeration, and improving beer taste and stability.
- Baking Improvement: Degrades gluten in dough, reducing its elasticity, resulting in more porous and shapeable biscuits and pastries, reducing the amount of oil and sugar used, and shortening the fermentation cycle.
- Seafood Production: Accelerates the autolysis of spent brewer's yeast sludge, extracting flavorful yeast extracts for use in soy sauce, seasonings, etc., increasing the extraction rate of flavor substances.
- Seafood Processing: Used for peeling and deboning squid, sea cucumber, and other seafood products, breaking down collagen in connective tissue and muscle fibers, improving efficiency and reducing nutrient loss.
2. Pharmaceutical Industry
- Digestive Aid: As a digestive enzyme preparation, it helps break down proteins in food, relieving symptoms such as indigestion, bloating, and stomach pain. It is often combined with lipase and amylase in compound preparations.
- Anti-inflammatory and Analgesic: Possessing anti-inflammatory properties, it can be used to relieve pain and swelling caused by soft tissue injuries such as arthritis, sprains, and contusions. Some topical creams contain papain.
- Wound Healing: Promotes wound healing, breaks down necrotic tissue, and reduces the risk of infection. It is commonly used for cleaning chronic ulcers and burn wounds, and needs to be used in conjunction with disinfectant.
- Antibody Engineering: In biopharmaceutical research and development, it is used to cleave the Fc and Fab fragments of immunoglobulins to prepare antibody-related products.
3. Feed Industry
- Improving the digestibility and absorption of feed protein in animals and promoting animal growth and development, especially with significant demand growth in the context of antibiotic-free feed transition.
4. Daily Chemical Industry
- Skincare Products: As an exfoliating ingredient, it gently removes dead skin cells, promotes skin metabolism, and improves rough skin and acne problems. It is often combined with urea and salicylic acid.
- Detergents: Added to soaps, detergents, and laundry powders to enhance cleaning power and help break down protein stains on clothing.
5. Leather and Textile Industry
- Leather Tanning: Used in pre-tanning treatments such as soaking, hair removal, liming, and softening to improve the softness and luster of leather.
- Textile Treatment: Treats wool, silk, and other fabrics, dissolving sericin, preventing shrinkage, and improving fabric feel and tensile strength.
6. Scientific Research and Biotechnology
- Used for cell isolation and culture, breaking down the extracellular matrix to obtain single-cell suspensions; also has applications in protein structure research and enzymatic synthesis.
Company introduction and certificates obtained
Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

Our packaging
1KG/Aluminium bags , 25kg/barrel
Storage: Store in a cool, dry, clean place away from moisture and direct light.
We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation

Our team
We have a professional R&D team and sales team, which not only ensure product quality, but also ensure a good cooperation experience for customers in the pre-sale, in-sale and after-sale processes. Our sales team has been trained in professional product knowledge, and can respond and solve every problem in cooperation in a timely manner


The payment methods we support are: T/T, VISA, XTransfer, Master Card, Western Union, Alibaba Payment, e-Checking, Online Bank Payment
We support shipping by sea, air, DHL, FedEx, TNT, UPS, EMS, SF

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