Ganoderma Lucidum Polysaccharide

Ganoderma lucidum polysaccharide is one of the most effective ingredients in Ganoderma lucidum. It has the characteristics of stimulating host nonspecific resistance, immune-specific response and inhibiting tumor physiological activity. Of course, some of these effects may also be related to other trace active ingredients in polysaccharide extracts, not just the unilateral effects of Ganoderma lucidum polysaccharide.
① Immunomodulation
Ganoderma lucidum polysaccharide can enhance delayed oversensitization to protein antigens by intraperitoneal injection or oral administration. Ganoderma lucidum polysaccharide can enhance the proliferation of T cells induced by concanavalin A in mice.
Ganoderma lucidum polysaccharide can promote the transformation of T lymphocytes and enhance cellular immunity; promote the formation reaction of lymphocytes to enhance humoral immunity; enhance the activity of DNA polymerase in lymphocytes, promote cell proliferation and division, lead to the synthesis and secretion of interleukins, and thus restore the decline in immunity caused by aging.
② Auxiliary anti-tumor
Ganoderma lucidum polysaccharide can become the preferred drug for anti-tumor and cancer auxiliary treatment by promoting the production of interleukin-2, promoting the phagocytic function of mononuclear macrophages, improving the body's hematopoietic ability, especially the level of white blood cell indicators, and inhibiting cancer cells through some of its active ingredients. Through experiments on mouse S180, it was found that the tumor inhibition rate of Ganoderma lucidum polysaccharide reached 57.4%, and there was a linear relationship between the dose and the tumor inhibition rate.
Studies have found that the anti-tumor activity of Ganoderma lucidum polysaccharide may be related to its effect on host function, and water-soluble polysaccharides may also play a more important role. At the same time, Ganoderma lucidum polysaccharide has a suitable molecular weight range. The larger the molecular weight, the stronger the anti-tumor activity.
③ Anti-aging
Ganoderma lucidum polysaccharide can promote the biosynthesis of nucleic acids and proteins in serum, liver and bone marrow, so it can effectively resist viruses; Ganoderma lucidum polysaccharide can significantly increase the activity of SOD and effectively remove free radicals produced by the body, thereby preventing free radicals from damaging the body, preventing the body from peroxidation, protecting cell tissues, and delaying cell aging.
Ganoderma lucidum polysaccharide can significantly promote the ability of DNA synthesis in the cell nucleus and increase the number of cell divisions. These effects can delay the aging of the body, so the anti-aging function of Ganoderma lucidum polysaccharide is very powerful.
④ Protect cardiovascular and cerebrovascular
Studies have shown that Ganoderma lucidum polysaccharide has a significant cardiotonic and antihypertensive effect, and has a preventive and auxiliary therapeutic effect on atherosclerosis. Ganoderma lucidum polysaccharide injected intraperitoneally into normal mice can lower blood sugar. The mechanism may be due to the increase in plasma insulin levels, accelerated glucose metabolism, and accelerated glucose utilization in external tissues and liver, thereby achieving the effect of lowering blood sugar.
Studies have confirmed that Ganoderma lucidum polysaccharide can effectively dilate coronary arteries, increase coronary blood flow, improve myocardial microcirculation, enhance myocardial oxygen and energy supply, significantly reduce blood cholesterol, lipoproteins and triglycerides, and prevent the formation of atherosclerotic hemispheres. It can also improve local microcirculation and inhibit platelet aggregation (the mechanism is still unclear).
⑤ Protect liver and detoxify
Ganoderma lucidum polysaccharide can promote the liver's metabolism of drugs and poisons, can significantly eliminate symptoms such as dizziness, fatigue, nausea, and discomfort in the liver area, and can effectively improve liver function and make various indicators tend to normal. Therefore, Ganoderma lucidum polysaccharide can be used as an auxiliary treatment for chronic liver poisoning, various types of chronic hepatitis, cirrhosis, liver dysfunction, etc.