Aronia Anthocyanins

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of aronia anthocyanins in China. With abundant experience, we warmly welcome you to wholesale bulk aronia anthocyanins for sale here from our factory. Quality products and reasonable price are available.

aronia anthocyanins is a wild fruit that belongs to the Rosaceae family and is native to the swamps of eastern North America. It is a particularly popular ornamental plant, but its fruit can be eaten by humans, processed into a variety of foods, and dried for medicinal purposes. The fruit of this plant contains a large amount of anthocyanins, which has a super health-promoting effect.
Aronia is used in the food industry for the production of juices, sauces, jams, fruit teas, and dietary supplements. Aronia is used not only in the food industry, but also as a herbal medicine. In Russia and Eastern European countries, it is often used as a natural antihypertensive and anti-atherosclerotic drug. The pungent, sour, bitter and unpleasant astringent taste of the raw fruit and the bitter almond flavor limit its use in juices and nectars. However, it can be mixed with juices, such as with apple, pear or black currant fruits. Aronia is used not only in the food industry, but also in the production of liqueurs and spirits, in addition to being an ingredient in fruit wine. During the fermentation of aronia, spirits with good flavor and taste can be obtained. Aronia shrubs are native to North America, where they are used medicinally to treat colds, coughs, and fevers. In addition, the plant contains polyphenols that exhibit antioxidant activity. Aronia berries contain high amounts of polyphenols and anthocyanins, which give them pharmacological properties and have been used to treat many human diseases such as cardiovascular disease, hyperlipidemia, hypercholesterolemia, hypertension, and diabetes.

Aronia fruit has been used as a food ingredient and therapeutic agent for many years. Various natural polyphenols such as anthocyanins found in several aronia varieties have many pharmacological properties such as antimutagenic and hypolipidemic properties. Aronia can also reduce the risk of many cardiovascular diseases; therefore, researchers have conducted a comprehensive study on the health benefits of aronia. Aronia berry extract (BCE) can exert protective effects on cognition and blood pressure in healthy middle-aged overweight adults. Anthocyanins present in aronia are sensitive to alkaline pancreatic digestion, which greatly moderates their bioavailability.

Antimutagenic Effect
Due to the presence of anthocyanins in aronia, they exhibit antimutagenic activity in vitro. Anthocyanins are also responsible for free radical foraging properties and the ability to inhibit enzymes, leading to mutagen activation. The results of the Ames test showed that anthocyanins isolated from aronia berries caused eradication mutagenic activity of benzo-2-aminofluorene. In addition, the chromosome exchange assay showed that BCE possessed noteworthy antimutagenic activity. The assay was conducted using human blood-derived lymphocytes cultured in vitro. Due to the high content of anthocyanins, the genotoxicity of benzo[a]pyrene and mitomycin C was reduced by 30% and 10%, respectively. Antimutagenic activity was also enhanced due to the presence of phenolic compounds in aronia. Moreover, mice injected with aronia juice induced with aminopyridine plus sodium nitrite showed a reduction in the production of endogenous N-nitrosamines. Thus, histopathological changes were seen in the liver of mice induced with nitrosamine precursors, which could be alleviated by co-treatment with aronia juice.
Anticancerous activity
Similar to other berries, aronia is rich in polyphenols and has antitumor potential in humans and animals. In recent years, many studies have been conducted to investigate the defense mechanism of aronia against cancer. Aronia is used in the treatment of breast cancer, intestinal cancer, and leukemia. There are also reports that aronia has a selective effect on cancer stem cells. Due to the high anticancer activity of phenolic compounds, which aronia berries are rich in, aronia juice is now produced as a healthy juice to supplement phenolic compounds for the human body. In a study, various cell lines, conditions and propagation times were used to understand the nature and mechanism of the anticancer activity of aronia. The results showed that although the anticancer activity of aronia was significant, it was not necessarily higher than that of other polyphenol-rich fruits. The undeniable anticancer activity was carried out through various mechanisms that rely on the reduction of oxidative stress, the regulation of chronic inflammation and the inhibition of enzymes that activate pro-inducing components and convert mutagens into active derivatives of DNA-reactive forms. These processes end numerous phases of the cell cycle, such as G1/G0, G2/M, and induce apoptosis and necrosis, thereby preventing the metastasis and development of cancer stem cells. BCE at 50 μg/mol showed a 10% inhibition rate in normal human colon cells and a 60% inhibition rate in human HT-29 colon cancer cells within 24 h. Prolonging the treatment time did not lead to changes in the cell number. The G1/G0 and G2/M phases of the cancer cell cycle after treatment showed a blockade. The results showed that aronia fruit juice (BCFJ) can inhibit the growth of cancer cells. A recent study investigated the effect of BCFJ on mouse embryonic carcinoma (EC) stem cells P19. BCFJ inhibited cell proliferation, induced cell cycle arrest at the S phase and triggered apoptosis, indicating that BCFJ can inhibit the carcinogenic process. Cell experiments and animal experiments have shown that aronia anthocyanidins (BCA) can inhibit the expression of COX-2 and MUC2 mRNA during colon carcinogenesis and reduce the secretion of related inflammatory cytokines. BCA inhibits the development of colon cancer by reducing the expression levels of GLS and SLC1A5, as well as reducing the phosphorylation levels of mTORC1 and its downstream targets and effector elements. Aronia obtained a breast cancer stem cell (CSC) inhibitor identified as catechol by fermentation with Lactobacillus rhamnosus. It is decomposed by tannic acid enzymes in lactic acid bacteria to obtain protocatechuol, which is then converted into catechol by decarboxylase. Catechol blocks the STAT3 signaling pathway and reduces the transcription and production of IL-6, a survival cytokine for CSCs. This process inhibits the proliferation of mammospheres. Aronia exhibits anticancer activity by changing the above biochemical processes. More studies have identified the anticancer potential of aronia. However, chemotherapy treatments may be adversely affected by the use of raw materials and products of plant origin. Therefore, it is necessary to study these effects in detail.
Free Radicals and Antioxidant Activity
When the balance between free radical generation and antioxidant defense is interrupted, oxidative damage usually occurs, which is described as oxidative stress. It is an important factor in the development of various diseases, such as heart disease, stroke, Alzheimer's disease and Parkinson's disease. Various antioxidants can reduce oxidative stress, they delay or inhibit the oxidation of specific substrates. In recent years, a large number of studies have shown that various natural products can act as good antioxidants. Studies have shown that the antioxidant potential of aronia berries is significantly higher than that of other berries. Studies have used the oxygen radical absorbance capacity (ORAC) value as an indicator of antioxidant potential, and the ORAC value of aronia berries is significantly higher than that of blueberries, black currants and cranberries. Aronia berries are rich in polyphenols, VC and VE, Cu and Zn. The presence of these supplements enhances the antioxidant potential of aronia berries. The antioxidant properties of highly purified anthocyanidins compared to a mixture of butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) or chokeberry were evaluated and found to be better than those of BHT and BHA. In addition to its antioxidant capacity, it also helps reduce the production of reactive oxygen species (ROS) and restores numerous antioxidant enzymes. In addition, it can also reduce oxidative stress damage caused by illness or physical exercise. Cases have shown that when a person consumes chokeberry juice, the damage to RBS is lower than in the control group. Chokeberry juice has a cardioprotective effect and can slow down atherosclerosis. It also has anti-aging properties. Undoubtedly, it is a health food with great potential for development.

Delaying aging
Aronia anthocyanidin is a natural antioxidant ingredient with a particularly strong antioxidant capacity. After the human body absorbs this substance, it can reduce the occurrence of oxidation reactions in the body, and can clean up the free radicals produced in the body and increase the activity of various tissue cells in the body. Regular consumption of aronia containing aronia anthocyanidin can play an important role in delaying aging and prolonging life.
Preventing vision loss
Aronia anthocyanidin has a very positive effect on human eyes. It can promote the production of rhodopsin in the retina of human eyes, and can prevent eye oxidation reactions and promote eye development. It has a certain preventive effect on dry eyes, astringent eyes, eye fatigue and vision loss that often occur in humans. In addition, regular consumption of aronia medicine can also prevent cataracts and glaucoma. It has very obvious benefits for maintaining human eye health.
Protect skin
Aronia anthocyanidins also have a significant protective effect on human skin. After the human body absorbs this anthocyanidin, it can increase the activity of elastase and collagenase in the body. These two enzyme substances can directly act on human skin cells, which can increase the elasticity of people's skin, make people's skin smooth and tender, reduce wrinkles and prevent skin aging. In addition, aronia anthocyanidins can repair damaged skin cells and improve the skin's sun protection ability.

YTBIO mainly supplies aronia anthocyanins etc. The company was established in 2014 and has many years of R&D and production experience. We are committed to the research and development, production and sales of raw materials for the 21st century health industry. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,etc. We always maintain the highest requirements for product quality.

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