Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of polygonatum extract in China. With abundant experience, we warmly welcome you to wholesale bulk polygonatum extract for sale here from our factory. Quality products and reasonable price are available.
About The Detailed Introduction Of Polygonatum extract?
Polygonatum extract is the dried rhizome extract of the Liliaceae plants Polygonatum kingianum Coll. et Hemsl., Polygonatum sibiricum Red. or Polygonatum cytoma Hua. It contains Polygonatum polysaccharide, amino acids, etc. It is often used to treat hypertension, coronary heart disease, leukopenia, aplastic anemia, drug-induced deafness, etc.
Contains a variety of active ingredients, mainly including polysaccharides, triterpene saponins, flavonoids, phenolic acids, etc. These substances have a variety of physiological activities and medicinal effects. For example, polysaccharides can enhance human immunity, lower blood sugar and blood lipids, and have antioxidant effects; triterpene saponins can regulate blood pressure, relax blood vessels, lower blood lipids, and have sedative, antihypertensive, and antidepressant effects; flavonoids and phenolic acids It has anti-inflammatory, antioxidant, and antibacterial effects.
Therefore, it is also widely used in the fields of medicine and health care products. It can be used as a natural immunomodulator to improve human immunity, prevent and treat infectious diseases; it can be used as a hepatoprotective agent to regulate liver function and repair liver damage; it can be used as a cardiovascular and cerebrovascular agent. Health care products are used to lower blood pressure, regulate blood lipids, and prevent arteriosclerosis and cardiovascular and cerebrovascular diseases; they can also be used as an antioxidant to reduce free radical damage, delay aging, and promote health.
In short, it is a healthy food raw material rich in natural nutrients and medicinal ingredients. It has a variety of physiological activities and medicinal effects and has been widely used in the fields of medicine and health products. As people's demands for health and nutrition continue to increase, the application prospects of polygonatum extract will become increasingly broad.
Main ingredients
Polygonatum mainly contains Polygonatum polysaccharides A, B, C, Polygonatum oligosaccharides A, B, C and steroidal saponins. It also contains more than 10 kinds of amino acids such as lysine, zinc, iron, selenium, niacin, mucilage, starch, and quinones.
1. Mucopolysaccharides: The mucopolysaccharide content of raw polygonatum is 11.74%, and the mucopolysaccharide content of prepared polygonatum is 3.77%. Polygonatum contains a lot of mucus. Polygonatum polysaccharides A, B, and C are formed by the condensation of glucose, mannan, and galacturonic acid; it also contains Polygonatum oligosaccharides A, B, and C, which are formed by the condensation of glucose and fructose. Polysaccharide polysaccharide is the main medicinal component of Polygonatum sibiricum, which can effectively improve the SOD activity of cells in the human body and the body's immunity. SOD can remove peroxide anions, reduce peroxide deposition in the body, resist aging, and lower blood lipids.
2. Steroidal saponins: Polygonatum contains steroidal saponins, including two furostenol-type saponins and two spirostenol-type saponins.
3. Others: Polygonatum also contains quinones, starch, and niacin; 6 kinds of essential amino acids and 8 kinds of essential trace elements. Polygonatum root contains azetidine-2-carboxylicacid, aspartic acid, homoserine, diaminobutyric acid, digitalis glycoside and various Anthraquinone compounds. Its leaves contain components such as vitexinxyloside and 5,4ˊ-dihydroxyflavone glycosides. Xinjiang Polygonatum rhizome contains 70.3% water-soluble neutral glucomannan and other ingredients. The underground part of Polygonatum angustifolia contains ingredients such as Diosgenin and β-sitosterol.
What Are The Benefits?
1. Anti-pathogenic microorganism effect
In vitro tests show that the water extract of Polygonatum sibiricum (1:320) has inhibitory effects on Typhoid bacilli, Staphylococcus aureus, and acid-fast bacilli, and 2% Polygonatum odorifera has varying degrees of inhibitory effects on common pathogenic fungi in Sabouraud culture medium.
2. Effect on blood sugar
When rabbits were given polygonatum extract by gavage, their blood sugar levels gradually increased and then decreased. Polygonatum extract has a significant inhibitory effect on hyperglycemia caused by epinephrine.
3. Anti-fatigue effect
Polygonatum decoction with a concentration of 17.67% and 0.3 ml/mouse intraperitoneally injected can prolong the swimming time of mice.
4. Antioxidant effect
Polygonatum decoction at a concentration of 20%, fed at 13 ml per animal for 27 consecutive days, increased the activity of superoxide dismutase (SOD) in the liver of mice and decreased the lipofuscin content in the myocardium.
5. Delay aging effect
Polygonatum decoction, soaked in mulberry leaves and fed to silkworms at a concentration of 20%, has the effect of prolonging the larval stage of silkworms.
6. Hemostatic effect
40 mg of methanol extract of Polygonatum japonica per animal, 20 mg of n-butanol part per animal, and 20 mg of aqueous layer part were injected intraperitoneally. The tails of mice were frozen in dry ice-methanol for 1 minute. The tail-cutting experiment showed that it has a hemostatic effect, so that The amount of bleeding in mice was reduced.
7. Effect on cardiovascular system
Polygonatum aqueous extract 0.16~0.26g/kg intravenously injected can significantly increase the coronary flow of anesthetized dogs; intravenous injection 1.5g/kg has an antagonizing effect on myocardial ischemia in rabbits caused by pituitrin. The increase in T wave promotes the early recovery of T wave abnormalities; intraperitoneal injection of 12 g/kg can enhance the tolerance of mice to hypoxia.
8. Antiviral effect
Polygonatum polysaccharide 0.2% eye drop drops, 6 times/day, or polygonatum polysaccharide 10 mg/kg, 2 times/day, have a therapeutic effect on experimental herpes simplex virus keratitis in rabbits.
9. Hypolipidemic effect
The extracts of polygonatum petroleum ether, ethanol, and water had a lowering effect on serum TC and TG in male SD rats to varying degrees than the control group, and the ethanol and water extracts had a more obvious effect on reducing serum TC and TG. Immunity-enhancing effect: Polygonatum sibiricum can promote the number of hemolytic plaques, rosette formation rate and lymphocyte transformation rate in mice. Clinically, polygonatum extract can increase lymphocyte transformation and E-rosette formation rates in some patients with low immune function. Kangbao oral liquid containing polygonatum as the main drug can also promote the synthesis of DNA in human blood lymphocytes and the proliferation of T lymphocytes. speed, to improve the immune function of lymphocytes and significantly enhance the phagocytic ability of macrophages.
10.Immune enhancement effect
Polygonatum extract can increase lymphocyte transformation and E-rosette formation rates in some patients with low immune function. Kangbao Oral Liquid, which uses Polygonatum as the main drug, can also promote the synthesis of DNA in human blood lymphocytes and the proliferation rate of T lymphocytes. It can improve the immune function of lymphocytes and significantly enhance the phagocytic ability of macrophages.
11. Effect on cardiovascular system
Intravenous injection of yellow semen into dogs can increase coronary flow without significant effects on heart rate, arterial pressure, and myocardial utilization; intravenous injection into rabbits can resist acute myocardial ischemia caused by pituitaryin; administration into isolated rabbit hearts Perfusion can enhance coronary flow; intraperitoneal injection of mice can enhance their tolerance to hypoxia. Polygonatum can increase the nutritional blood flow of mouse myocardium, and has cardiotonic effects on isolated normal and failing toad hearts. Intraperitoneal injection of Polygonatum alcohol extract in mice can promote the incorporation of thymidine into myocardial DNA. Studies have shown that polygonatum can significantly promote recovery from the inhibition of hematopoietic function in animals irradiated with 60 cobalt.
12.Other functions
Intragastric administration of Polygonatum decoction can increase the Na+, K+-ATPase activity of red blood cell membranes in mice. Intraperitoneal injection of 0.3 mg/mouse of 40% polygonathol extract can increase the incorporation rate of 3H-TdR into DNA of mouse myocardium, liver, and spleen tissue cells. Intragastric administration of 0.5 g of Polygonatum decoction/mouse caused the plasma cAMP and cGMP contents of mice to decrease, and cGMP decreased more, so the cAMP/cGMP ratio was greater than that of the control group. The cAMP and cGMP contents of spleen tissue increased, but cAMP/cGMP There is no significant change in the ratio.
13. Immune regulation: Rich in polysaccharide compounds, this substance can enhance human immunity, promote the activity of macrophages and lymphocytes, and enhance cellular immunity and humoral immunity.
14. Cardiovascular and cerebrovascular health care: It is rich in triterpene saponins, which can lower blood pressure, regulate blood lipids, expand blood vessels, and help prevent arteriosclerosis and cardiovascular and cerebrovascular diseases. At the same time, it also has sedative, antihypertensive, antidepressant and anti-anxiety effects, which can help relieve stress and improve sleep quality.
15. Liver protection: The triterpene saponins in Polygonatum sibiricum extract can promote bile secretion and facilitate bile excretion, digestion and absorption. In addition, it can also reduce liver cell damage and repair damaged liver cells, protecting liver health.
16. Anti-inflammatory and antioxidant: Rich in flavonoids and phenolic acid compounds, these substances have various effects such as antioxidant, anti-inflammatory, and antibacterial. They scavenge free radicals and reduce inflammation, helping to prevent disease and promote good health.
17. Nerve health care: It can improve the body's metabolism and neurotransmitter levels, promote the stability and development of brain function, and prevent and improve diseases such as Alzheimer's disease and neurasthenia.
18. Protect skin: Contains a variety of natural phytonutrients and antioxidant substances, which can inhibit the production of melanin, prevent skin aging and the formation of spots.
What Are The Application Directions?
Pharmaceutical field: widely used in the pharmaceutical field. It can be used to prepare traditional Chinese medicine formulas to treat various diseases, such as hepatitis, hypertension, diabetes, cardiovascular and cerebrovascular diseases, etc. Its anti-inflammatory, antioxidant, immunomodulatory and liver-protecting effects are used in drug development and clinical treatment.
Health care product field: Due to its various health care effects, it is widely used in the health care product field. The immune modulation, cardiovascular and cerebrovascular health care, anti-inflammatory and antioxidant effects of Polygonatum japonica extract can be used to enhance immunity, improve cardiovascular health, relieve stress and improve sleep quality.
Cosmetic field: used in cosmetics for skin care, whitening and delaying skin aging. It has the effects of antioxidant, inhibiting melanin production and reducing spots, which can improve skin quality and protect skin health.
Food field: It can be used as a natural food additive to increase the nutritional value and functionality of food. For example, it can be added to nutraceuticals, functional beverages and dairy products to provide immune modulation, cardiovascular health and antioxidant benefits.
Beverage field: It can be added as a natural plant extract to various beverages, such as tea, juice and functional drinks, to increase the functionality and nutritional value of the product. It can enhance the antioxidant capacity, immunomodulatory effect and cardiovascular and cerebrovascular health effects of the beverage.
Health care field: It is widely used in the field of health care. It can be made into health products, tonics and herbal drinks to enhance physical health, delay aging and improve physical fitness.
Company introduction and certificates obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
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