What Is J-147 Powder?

J-147 powder is a particularly potent, orally active neuroprotectant that enhances cognitive performance. Can cross the blood-brain barrier (BBB). Inhibits monoamine oxidase B (MAO B) and dopamine transporter with EC50 of 1.88 μM and 0.649 μM, respectively. J-147 has the potential to be used in Alzheimer's disease (AD) research.

J-147 Powder

J-147 powder is derived from curcuminoids and cyclohexyl bisphenol A. Has neuroprotective and neurogenic properties. Unlike most other nootropics, J-147 anti-aging supplement enhances cognitive performance without affecting acetylcholine or phosphodiesterase.

Product Details Form

CAS	1146963-51-0
Molecular formula	C18H17F3N2O2
Molecular weight	350.33
EINECS	1592732-453-0
Boiling point	412.8±55.0°C (Predicted)
Density	1.18±0.1g/cm3(Predicted)
Solubility	DMSO: 68.0(MaxConc.mg/mL); 194.1(MaxConc.mM)
Acidity coefficient (pKa)	0.80±0.50(Predicted)

How Does J-147 Work?

In 2018, neurobiologists at the Salk Institute studied the effects of J-147 on cells. This drug works by binding to ATP synthase. This mitochondrial protein regulates cellular energy production, thereby controlling the aging process.

Presence in human systems protects against age-related toxicity due to mitochondrial dysfunction and ATP overproduction.

J-147's mechanism of action will also increase levels of various neurotransmitters, including NGF and BDNF. It also acts on beta-amyloid levels.
Actions of J-147 include slowing the progression of Alzheimer's disease, preventing memory deficits and increasing the production of neuronal cells.

What Are The Benefits?

1. Improve awareness
J-147 supplementation enhances spatial and long-term memory. Cognitive deficits can be reversed in older adults with cognitive impairment.
Taking J-147 anti-aging medicine will also enhance memory, eyesight and mental clarity.

2. Management of Alzheimer's disease

J-147 benefits Alzheimer's patients by slowing disease progression. For example, taking supplements reduces levels of soluble beta-amyloid (Aβ), which can lead to cognitive impairment. Furthermore, J-147 curcumin modulates neurotrophin signaling to ensure neuronal survival and thus memory formation and cognition.
AD patients do have less neurotrophic factors. However, taking the J-147 Alzheimer's supplement boosts NGF and BDNF. These neurotransmitters contribute to memory formation, learning and cognitive function.

3. Neuroprotection
J-147 nootropic prevents neuronal death induced by oxidative stress.
This supplement also blocks overactivation of NMDA (N-methyl-D-aspartate) receptors, which is what causes neurodegeneration.
Taking the drug J-147 increases brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). These two neurotransmitters can inhibit neurodegenerative diseases such as Alzheimer's and dementia. More importantly, BDNF is important in neurogenesis.
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4. Improves Mitochondrial Function

Taking the drug J-147 will indirectly increase ATP levels by enhancing mitochondrial function.
Aging is responsible for mitochondrial decline due to dysfunction and increased reactive oxygen species. However, J-147 supplementation counteracts this mechanism by inhibiting ATP5A synthase.

J-147 And Anti-Aging

Dysfunctional mitochondria accelerate the aging process. Cellular homeostasis will be reduced and, therefore, physiological activity will be reduced. In addition, cell damage and mitochondrial deterioration will follow due to the generation of ROS (reactive oxygen species). Taking J-147 powder will counteract this effect, thereby slowing down aging.

Aging is also associated with cognitive decline and neurodegenerative diseases. However, multiple J-147 experiences have demonstrated the drug's efficacy in reversing memory loss, improving cognition, and treating dementia, Alzheimer's, and other age-related diseases.

J-147 powder

Company introduction and certificates obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

certificate