Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of o-phospho-l-serine in China. With abundant experience, we warmly welcome you to wholesale bulk o-phospho-l-serine for sale here from our factory. Quality products and reasonable price are available.
Products Description
L-O-phosphoserine is a phosphorylated derivative of serine, in which the phosphate group is linked to the hydroxyl group of the serine side chain via an ester bond. It is an important metabolic intermediate and signaling molecule in living organisms.
It is a white crystalline powder, readily soluble in water. L-O-phosphoserine can be used for protein expression, purification, and phosphorylation studies, as well as for investigating chemical shifts and determining its pKa value using Raman spectroscopy.
| Item | Specification |
|---|---|
| English Name | O-Phospho-L-serine |
| CAS Number | 407-41-0 |
| Molecular Formula | C₃H₈NO₆P |
| Molecular Weight | 185.07 g/mol |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water (approximately 50 mg/mL, clear to pale yellow solution after heating) |
| Melting Point | 190 °C (literature value) |
| Specific Rotation | [α]D²⁰ = +14～+18° (c=5, dilute HCl) |
What are the benefits?
L-O-phosphoserine possesses the following key biological activities:
Neural Signal Regulation
As a regulator of metabolized glutamate receptors (mGluR), L-O-phosphoserine can activate group III mGluRs (such as mGluR4, mGluR6, mGluR7, and mGluR8) while antagonizing mGluR1 and mGluR2. This may affect nerve cell signal transduction and play a role in the functional regulation of the nervous system, but its specific physiological significance requires further investigation.
Cell Proliferation and Differentiation Regulation
In retinal studies, L-O-phosphoserine has been found to inhibit the proliferation of Müller glial cells, potentially affecting retinal cell regeneration and repair processes. However, whether this effect applies to other tissues or physiological scenarios remains unclear.
As a direct precursor to L-serine synthesis: it participates in amino acid metabolic pathways.
Metabolic glutamate receptor (mGluR) modulators:
- Agonists of Group III mGluRs (mGluR4, mGluR6, mGluR7, mGluR8);
- An antagonist of Group I mGluRs (mGluR1, mGluR2), especially showing stronger inhibition of mGluR2 (Ki ≈ 1 μM).
Neural and retinal regulation:
- Inhibits Müller glial cell proliferation;
- Inhibits cone cell regeneration in the retina after light damage;
- Does not affect photoreceptor cell death.
Main Application Areas
- Neuroscience Research: Used to study glutamatergic signaling pathways and neurodegenerative diseases.
- Materials Science: Can be used as a ligand in the synthesis of chiral cobalt(II) coordination polymers, possessing potential value in magnetic materials.
- Cosmetic Ingredients: Possesses skin conditioning and hair care benefits.
- Analytical Detection: Quantitative analysis is commonly performed using HPLC or LC-MS methods.
Company introduction and certificates obtained
Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
packaging
1KG/Aluminium bags , 25kg/barrel
Storage: Store in a cool, dry, clean place away from moisture and direct light.
We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation
→CONTACT US
For more product information and pricing details about O-Phospho-L-serine, please feel free to contact the YTBIO team.
tel/ Whatsapp:86 177 8257 7059
email:sales@sxytbio.com
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