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Bee Venom Powder

Bee Venom Powder

Name:Bee venom/Melittin
Specifications:40%,70%
CAS No.: 20449-79-0
Delivery cycle:3-5 days
Sales group:not for individual customers
Inventory:In stock
Certificates:cGMP,BRC,FSSC22000, HALAL, KOSHER, ISO9001, ISO22000, FDA
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Product Introduction

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of bee venom powder in China. With abundant experience, we warmly welcome you to wholesale bulk bee venom powder for sale here from our factory. Quality products and reasonable price are available.

 

What is Bee Venom Powder?

Bee

Bee Venom Powder is the main active ingredient of bee venom. Bee venom is a transparent venom with an aromatic smell secreted by the venom glands and accessory glands of worker bees. It is discharged from the stinger when it is invaded. Among the many components of bee venom, melittin has the highest content, accounting for about 50% of the dry weight of bee venom, and it has high biological activity. Melittin is a linear peptide composed of 26 amino acids with a relative molecular weight of 2849. Modern pharmacological studies have shown that it has multiple effects such as anti-inflammatory, analgesic, platelet aggregation inhibition, and anti-AIDS. Melittin can produce a strong killing effect on a variety of tumor cells through different mechanisms. It is a natural anti-tumor drug with great application prospects.

Product details

 

CERTIFICATE OF ANALYSIS

Product Name:Bee venom

Botanical Source:Apis mellifera

Item

Specification

Results

Active peptide

40%

43.19%

Appearance

Brown powder

Complies

Odor & taste

Characteristic

Complies

Mesh size

100% pass 80 mesh

Complies

Loss on drying

≤8.0%

7.55%

Total ash

≤2.0%

1.33%

Heavy metals

≤5PPM

Complies

As

≤1PPM

Complies

Total Plate Count

<1000cfu/g

28cfu/g

Yeast & Mold

<100cfu/g

5cfu/g

E.Coli

<Negative

Complies

S.Aureus

<Negative

Complies

Salmonella

<Negative

Complies

Conclusion

Conform with specification

Please contact us at sales@sxytbio.com for further Bee Venom Powder specifications and technical data.

 

The anti-inflammatory mechanism

 

The anti-inflammatory mechanism of melittin lies in its ability to inhibit IKK and IκB phosphorylation, thereby blocking the nuclear transcription of NF-κB and downregulating the expression of pro-inflammatory factors such as TNF-α, IL-1β, and IL-6, thus disrupting the positive feedback loop of inflammation. Simultaneously, it can inhibit JNK and p38 phosphorylation and downregulate Toll-like receptor expression, hindering MAPK pathway activation and synergistically reducing the inflammatory response with the NF-κB pathway. Furthermore, melittin can induce synovial cell apoptosis and alleviate synovial inflammation by interfering with STAT transcription factor activity, and inhibit inflammatory protein expression by inhibiting Akt phosphorylation, thereby suppressing neuroinflammation and exerting a synergistic anti-inflammatory effect at multiple levels.

 

The main anti-inflammatory mechanism of bee venom
The main anti-inflammatory mechanism of bee venom

Other Activities

Antibacterial and Antiviral Effects

melittin has inhibitory effects on various Gram-positive and Gram-negative bacteria. Its antiviral mechanism mainly involves disrupting the viral envelope structure, inhibiting viral entry into host cells, and regulating the host immune response.

Analgesic Effects
Its analgesic effect is non-addictive. It can also enhance the body's ability to repair radiation damage and reduce radiation-induced oxidative stress and tissue damage.

 

Conclusions and Outlook

 

Melittin are the main active components of bee venom, possessing diverse pharmacological activities. Current research primarily focuses on their anti-tumor and anti-inflammatory effects. Their anti-inflammatory activity has been proven effective in treating various inflammatory diseases, demonstrating good efficacy and potential for clinical development.

 

Most existing detoxification measures target the hemolytic toxicity of melittin, while reports on reducing other toxicities such as pain and sensitization are scarce. Therefore, effectively reducing the various adverse reactions of melittin and improving therapeutic efficacy remains a crucial issue that urgently needs to be addressed.

 

contact us

 

YTBIO mainly supplies Bee Venom Powder etc. The company was established in 2014 and has many years of R&D and production experience. We are committed to the research and development, production and sales of raw materials for the 21st century health industry. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,etc. We always maintain the highest requirements for product quality.

 

Contact us now for samples, technical information, and customized quotes.

Telephone/WhatsApp:+8617782577059

Email:sales@sxytbio.com

 

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