Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of l-threonine powder in China. With abundant experience, we warmly welcome you to wholesale bulk l-threonine powder for sale here from our factory. Quality products and reasonable price are available.
What Are L-Threonine?
Threonine is an organic compound with a chemical formula of C4H9NO3. It has optical activity and is an essential amino acid. It is mainly used in medicine, chemical reagents, food fortifiers, and feed additives.
L-Threonine Powder is produced by W. C． Rose, which was isolated and identified from fibrin hydrolyzate in 1935, has been proved to be the last essential amino acid discovered. It is the second or third limiting amino acid of livestock and poultry, and it has extremely important physiological functions in animals. Such as promoting growth, improving immune function, etc.; balancing dietary amino acids, making the ratio of amino acids closer to ideal protein, thereby reducing the requirements of livestock and poultry for protein content in feed. Lack of threonine can lead to symptoms such as reduced animal feed intake, stunted growth, decreased feed utilization, and suppressed immune function. In recent years, synthetic products of lysine and methionine have been widely used in feed, and threonine has gradually become a limiting factor affecting animal production performance. Further research on threonine will help effectively guide livestock and poultry production.
Threonine is an amino acid that cannot be synthesized by animals, but is very much needed. It can be used to precisely balance the amino acid composition of feed, meet the needs of animal growth and maintenance, increase weight gain and lean meat rate, and reduce feed-to-meat ratio; it can improve amino acid digestibility The nutritional value of low feed raw materials can improve the production performance of low-energy feed; it can reduce the crude protein level of feed, improve the nitrogen utilization rate of feed, and reduce feed cost; it can be used for feeding and breeding of pigs, chickens, ducks and high-grade aquatic products. L-threonine is a feed additive produced by submerged fermentation and refining of cornstarch and other raw materials using the principle of bioengineering. It can adjust the amino acid balance in the feed, promote growth, improve meat quality, improve the nutritional value of feed materials with low amino acid digestibility, and produce low-protein feed, which helps to save protein resources, reduce the cost of feed materials, and reduce livestock manure and urine. Nitrogen content, ammonia concentration and release rate in livestock and poultry houses. It is widely used to add piglet feed, breeding pig feed, broiler chicken feed, prawn feed and eel feed.
Product Details Form
| CAS | 72-19-5 |
| Molecular formula | C4H9NO3 |
| Molecular weight | 119.12 |
| EINECS | 200-774-1 |
| Melting point | 256°C (dec.) (lit.) |
| Specific rotation | -28.4º(c=6,H2O) |
| Boiling point | 222.38°C (rough estimate) |
| Density | 1.3126 (roughestimate) |
| Refractive index | -28°(C=6, H2O) |
| FEMA | 4710|L-THREONINE |
| Solubility | H2O:50mg/mL |
| Acidity coefficient (pKa) | 2.09 (at25°C) |
| PH value | 5-6 (100g/l, H2O, 20°C) |
What Are The Benefits?
1. Among the 8 essential amino acids required by humans and animals, threonine is the fourth amino acid after methionine, lysine, and tryptophan. Threonine plays an important role in human growth and development, and L-threonine is necessary to maintain nitrogen balance in the body and promote normal growth and development. In addition, it also plays a role in maintaining the functions of the cardiovascular, liver, central nervous system, intestines, and immune system.
2. Threonine is needed for the body to produce glycine and serine, two amino acids that the body needs to produce collagen, elastin, and muscle tissue. It helps keep connective tissues and muscles throughout the body strong and elastic, and high amounts of this nutrient can be found in the heart. Other benefits of threonine include building strong bones and tooth enamel, and speeding wound healing and recovery from injury.
3. Threonine combined with aspartic acid and methionine helps the liver resist fat and enhance the function of digesting unsaturated fat. The lack of sufficient threonine in the human body will cause the liver to form a large amount of fat and eventually lead to liver failure.
4. Threonine supports the immune system through the production of antibodies, and because it exists in large amounts in the central nervous system, it has a certain effect on the treatment of certain types of depression. In addition, it has the effect of treating amyotrophic lateral sclerosis (because it can increase the level of glycine in the central nervous system). Studies have found that the symptoms of multiple sclerosis, a disease that affects nerve and muscle function, can be alleviated by taking a threonine nutritional supplement [4].
5. Threonine has the function of transforming certain amino acids to achieve balance, so it can balance dietary amino acids and make the ratio of amino acids closer to ideal protein, thereby reducing the biological requirements for protein content in food. In this regard, threonine is unique among the 20 amino acids.
6. In the catabolism of threonine in the body, it is the only one that does not undergo deamination and transamination, but is directly catalyzed by threonine dehydratase, threonine dehydrogenase and threonine aldolase. Amino acids of other substances, such as threonine, can be converted into butyryl-CoA, succinyl-CoA, serine, glycine, etc. In addition, excessive threonine can increase the activity of lysine-α-ketogluconate reductase. Adding an appropriate amount of threonine to the diet can eliminate the decrease in body weight caused by excessive lysine, and protein in liver and muscle tissue / deoxyribonucleic acid (DNA), ribonucleic acid (RNA) / DNA ratio decreased. Addition of threonine also alleviated growth inhibition caused by excess tryptophan or methionine.
7. Supports Digestive Health
Threonine protects the digestive tract by creating a mucus gel layer that covers it and acts as a barrier to damaging digestive enzymes. This important amino acid also supports healthy gut function by promoting the protection of the intestinal mucus barrier.
According to research published in Frontiers in Biological Sciences, the majority of dietary threonine is used for intestinal mucosal protein synthesis. For this reason, consumption of threonine foods may help improve gut health in both physiological and pathological conditions in humans and animals.
8. Boosts the immune system
We need enough Thr to support proper immune function. The thymus uses essential amino acids to make T cells, or T lymphocytes, which fight off infections in the body.
The study, published in Cold Spring Harbor Perspectives in Biology, states that "serine/threonine kinases control the epigenetic, transcriptional and metabolic programs that determine T cell function." At a fundamental level, serine and threonine Acid kinases function as a series of on/off switches that trigger the antigen and cytokine receptors that make up the immune system.
9. May Improve Muscle Contraction
The amino acid threonine increases glycine levels in the central nervous system.
Glycine is used to treat spasticity, which is why L-threonine has been evaluated for its ability to improve spasticity, or muscle contraction, in ALS patients.
10. Supports Muscle and Bone Strength
Did you know that collagen and elastin require threonine for proper production? You probably already know that collagen is the most abundant protein in the body, found in our muscles, bones, skin, blood vessels, tendons and digestive system.
Because Thr produces collagen, it plays a vital role in bone and muscle health.
11. Helps Prevent Fatty Liver
The amino acid threonine prevents fat accumulation in the liver. It does this by regulating fat metabolism and promoting lipophilic function.
Liptropic compounds break down fat during metabolism, which would not be possible without the amino acids threonine, methionine and aspartate. Threonine deficiency can lead to fatty liver and even liver failure.
12. May Reduce Anxiety and Mild Depression
Changes in serum levels of amino acids, including serine and glycine, which require Thr for production, are associated with major depressive disorder, research suggests. Researchers in Belgium have found that changes in the levels of threonine, aspartate, asparagine and serine can predict a patient's response to antidepressant treatment by modulating amino acid levels in the body.
Because Thr is a precursor to glycine, which helps calm the nerves and support cognitive health, it's often taken as a supplement to relieve signs of anxiety and depression. Glycine is also known for its ability to help improve sleep, mental performance, mood, and memory.
13. Speeds up wound healing
Threonine is required for normal production of collagen, which is required for connective tissue formation and wound healing.
Studies have shown that individuals have greater urinary threonine leakage after experiencing burns or trauma. This suggests that amino acids are metabolized from body tissues after injury.
Increasing Thr intake through amino acid T foods or supplements may help accelerate the healing of wounds, burns, and other forms of trauma.
What Are The Application Directions?
L-threonine powder can be widely used in medicine, nutrition and health care, food fortifiers, feed additives, beauty and daily chemicals, etc.:
1. Food nutritional supplements
Threonine is an important food fortifier, added to food, can improve the nutritional value of protein, can strengthen cereals, cakes, dairy products, and like tryptophan, it can restore human fatigue, promote growth and development, and make food nutritious The ingredients are more sufficient and reasonable. Co-heating threonine and glucose can produce caramel and chocolate aromas, which have a flavor-enhancing effect. Together with other amino acids, it is used to fortify cereals, cakes, infant food, and milk to play an antioxidant role.
2. Threonine, lysine, methionine, and tryptophan are known as the four major feed additives.
In recent years, the amount of feed additives has increased rapidly. It is often added to the feed of young piglets and poultry. It is the second limiting amino acid in pig feed and the third limiting amino acid in poultry feed.
Cereal protein needs to be supplemented with L-lysine, followed by L-threonine. This is because although the content of L-threonine is relatively high, the combination of threonine and peptide in protein is difficult to be hydrolyzed and difficult to digest and absorb. Adding L-threonine to wheat, barley and other grain-based feed formulas has the following characteristics:
① It can improve the biological value of feed protein, adjust the amino acid balance of feed, and promote the growth of poultry and livestock;
②Promote protein deposition and improve meat quality;
③ It can improve the nutritional value of feed with low amino acid digestibility;
④Reduce animal ammonia excretion, reduce environmental pollution, improve feeding conditions, and reduce feed raw material costs;
Therefore, it has been widely used in the feed industry in EU countries (mainly Germany, Belgium, Denmark, etc.) and American countries.
3. Pharmaceutical field
(1) Because threonine contains hydroxyl groups in its structure, it has a water-holding effect on human skin, combines with oligosaccharide chains, plays an important role in protecting cell membranes, and can promote phospholipid synthesis and fatty acid oxidation in the body.
(2) Threonine iron salt can be used as an anti-anemia drug for amino acid infusion and comprehensive amino acid preparations. It also has the effects of promoting human development and anti-fatty liver. .
(3) Threonine has the function of improving immunity and promoting the differentiation and development of bone marrow T lymphocyte precursors into mature T lymphocytes.
(4) The hydroxyl group of threonine in the membrane protein can combine with oligosaccharides to protect the cell membrane. Threonine is metabolized to glycine, which provides the one-carbon unit.
(5) For the adjuvant treatment of peptic ulcer. It can also treat cardiovascular system diseases such as anemia, angina pectoris, aortitis, and cardiac insufficiency.
(6) Threonine is also a raw material for the manufacture of a class of highly effective and hypoallergenic antibiotics - monoamicin.
4. Nutritional infusion
Threonine is widely used in the preparation of amino acid infusions and comprehensive amino acid preparations, and is the main component of 11, 14, 17, 18, and 20 amino acid infusions. It is used for adjuvant treatment before and after surgery, trauma, burns, fractures, malnutrition, and chronic wasting diseases.
5. Beauty products
Threonine has a water-holding and moisturizing effect on human skin. The structure of threonine contains hydroxyl groups, and through the hydration of hydrogen bonds, it plays a role in water retention and moisturizing for human skin.
Threonine helps maintain proper balance in the body and aids in the formation of collagen and elastin, strengthening the skin's structure.
In the membrane protein, the hydroxyl group of threonine can be combined with the oligosaccharide chain, which plays an important role in protecting the cell membrane, and can promote the synthesis of phospholipid and the oxidation of fatty acid in the body.
Company introduction and certificates obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying L-threonine powder etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
Our packaging
Our team
Factory
Payment method
Shipping method
Client feedback
Hot Tags: l-threonine powder, China l-threonine powder manufacturers, suppliers, factory
