Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of calcium pantothenate powder in China. With abundant experience, we warmly welcome you to wholesale bulk calcium pantothenate powder for sale here from our factory. Quality products and reasonable price are available.
What is calcium pantothenate?
Calcium pantothenate is a type of B vitamin and one of the nutrients necessary for normal growth of organisms. Calcium pantothenate exists in three forms due to its chiral carbon atom: DL-body (mixed body), D-body (dextrose body) and L-body (levorotatory body). Only D-calcium pantothenate has biological activity. It appears as white or slightly yellow needle-shaped crystals or powder, with a melting point of 195-196°C (decomposition). It is soluble in water, methanol, glycerol, slightly soluble in ethanol and acetone, hygroscopic, slightly sweet, but slightly bitter. In terms of chemical stability, it is most stable in aqueous solutions with a pH value of 5 to 7. It is relatively stable in air and sunlight, but less stable in acid and alkali.
Pantothenic acid is a component of coenzyme A. It plays an important role in the metabolism of fat, protein and sugar in the body. It has the function of making antibodies and also plays an important role in maintaining the health of hair, skin and blood. The main form of pantothenic acid is D-calcium pantothenate, which is widely used in food, medicine and feed additives.
Odorless, slightly bitter; hygroscopic; aqueous solution shows neutral or weak alkaline reaction. Easily soluble in water, very slightly soluble in ethanol, almost insoluble in chloroform or ether. It has the function of producing antibodies and also plays an important role in maintaining the health of hair, skin and blood.
What are the benefits?
1. Promote sebum secretion
Calcium pantothenate powder can regulate cell metabolism and differentiation, thereby affecting the function of sebaceous glands. Appropriate supplementation of calcium pantothenate can promote sebum secretion and help maintain skin health.
2. Improve skin moisture content
It can increase the water content of the stratum corneum and enhance the skin's ability to retain water. Oral or topical calcium pantothenate products can be used to increase skin moisture content, which is suitable for dry, rough and other skin problems.
3. Anti-inflammatory effect
It has non-specific anti-inflammatory effects and can reduce inflammatory reactions.
4. Inhibit melanin formation
It can interfere with the biosynthesis process of melanin and reduce pigmentation.
5. Enhance skin barrier function
It can promote keratinocyte proliferation and differentiation, thereby enhancing skin barrier function. Mainly through topical calcium pantothenate preparations to strengthen skin protection and prevent the invasion of external irritants.
As a B vitamin, D-pantothenate calcium is widely used in the medical field. Its single preparation is mainly indicated for pantothenic acid deficiency, while its compound preparation is widely applicable to gastrointestinal diseases, respiratory diseases, skin diseases, mental depression, neurasthenia, etc. In addition, it can also be used in health products, and the consumption demand of D-pantothenate calcium in this field is growing fastest. With the continuous enhancement of people's health awareness, the consumption of health products will also increase greatly, which will inevitably drive the growth of D-pantothenate calcium consumption.
D-pantothenate calcium is also a component of coenzyme A, which participates in regulating the metabolism of protein, sugar and fat, improving hair color and preventing diseases. In particular, the growth and development of poultry, livestock and fish, and the synthesis and decomposition of fat are indispensable for the demand for D-pantothenate calcium. Ruminants such as sheep and cattle can synthesize pantothenic acid by themselves, and monogastric animals such as pigs and chickens and fish can also synthesize a small amount of pantothenic acid, but it cannot meet their own growth needs. Lack of pantothenic acid will lead to slow growth of poultry and livestock, reproductive dysfunction and reduced adaptability. Therefore, D-calcium pantothenate is also widely used in the feed industry as a feed additive. Currently, about 75% of D-calcium pantothenate in the domestic and foreign markets is used as a poultry and livestock feed additive.
Limited Use
Pantothenic acid is widely present in food, but it will be lost in large quantities during the processing process. Therefore, D-calcium pantothenate is often added to food as a nutritional enhancer to promote human health and improve mental adaptability. In addition, D-calcium pantothenate can also be added to shochu and whiskey to enhance the flavor, added to honey to prevent winter crystallization, and can also alleviate the bitterness of caffeine and saccharin. Therefore, D-calcium pantothenate should be appropriately added to some fortified foods. The "Sanitary Standards for the Use of Food Nutrition Fortifiers" (GB14880-94) of the Ministry of Health of my country stipulates that 15-28 mg of D-calcium pantothenate (calculated as pantothenic acid) should be added to each kilogram of infant food and 2-4 mg of D-calcium pantothenate (calculated as pantothenic acid) should be added to each kilogram of drinking liquid.
Preparation method
A method for preparing calcium D-pantothenate, comprising:
Step 1: 3-aminopropionitrile and sodium hydroxide or potassium hydroxide aqueous solution react at 96 to 100°C, add hydrochloric acid to adjust the pH value, concentrate and crystallize to obtain crystals;
Step 2: Take the crystals obtained in step I and add methanol to dissolve, filter and collect the filtrate;
Step 3: Take the filtrate obtained in step 2 and add 732 type calcium ion exchange resin to carry out ion exchange reaction, and collect the reaction liquid;
Step 4: Take the reaction liquid obtained in step 3 and add D-pantothenate lactone to carry out acylation reaction, crystallize at -15 to -10°C, and dry to obtain calcium D-pantothenate; wherein the molar ratio of the 3-aminopropionitrile to sodium hydroxide and potassium hydroxide is 1:1.1 to 1.4, and the molar ratio of the 3-aminopropionitrile to D-pantothenate lactone is 1:1 to 1.1; the pH value is adjusted to 8.5 to 9.5 by adding hydrochloric acid in step I.
Company Introduction
Founded in 2014, YTBIO mainly supplies food additives such as Calcium Pantothenate Powder, herbal extracts, functional cosmetic raw materials, organic products, etc. All of our products are produced by ourselves. At present, our certificates include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, etc. All our products have been tested and we support third-party testing. We provide a variety of products, for any detailed information about the products, please click sales@sxytbio.com Contact us, we will have professional sales staff to give you detailed answers
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