Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of sinensetin powder in China. With abundant experience, we warmly welcome you to wholesale bulk sinensetin powder for sale here from our factory. Quality products and reasonable price are available.
Product Description
Sinensetin Powder (chemical name 5,6,7,3',4'-pentamethoxyflavonoids) are flavonoid compounds found in the fruits and juices of citrus plants. Their
molecular formula is C20H20O7, CAS number is 2306-27-6, and molecular weight is 372.37. Other names include 3',4',5,6,7-pentamethoxyflavonoids. They are mainly derived from Rutaceae plants such as dried tangerine peel, citrus peel, and Guangchenpi. This compound possesses antibacterial, anti-inflammatory, anti-allergic, antiviral, analgesic, cardiovascular disease prevention, and antioxidant effects. It can improve lung tissue damage caused by respiratory syncytial virus infection through the AMPK/mTOR signaling pathway. Studies have shown that it can inhibit the proliferation of HCT116 colon cancer cells, arrest the cell cycle in the G1 phase, and upregulate the expression of p53 and p21 proteins. In terms of anti-diabetic effects, sweet orange flavonoids can reduce blood glucose and insulin resistance in obese patients with type 2 diabetes and protect kidney function.
The detection method is high-performance liquid chromatography (HPLC), and the ultraviolet detection wavelength is 270 nm. As a research reagent, its purity is ≥98%, and it must be stored at 2-8℃.
- The detection method is high-performance liquid chromatography (HPLC).
- The ultraviolet detection wavelength is 270 nm.
- As a research reagent, its purity is ≥98%, and it needs to be stored at 2-8℃.
- Physical properties: Boiling point approximately 547.8°C, density 1.244 g/cm³.
- Solubility: Soluble in organic solvents such as methanol, ethanol, and DMSO; partially soluble in water.
- Natural sources: Primarily found in the fruits, juices, and peels of citrus plants. It is also present in traditional Chinese medicines such as tangerine peel, immature bitter orange, and dried tangerine peel. Additionally, it has been found in the plant *Orthosiphon spicatus.
What are the benefits?
1. Anti-inflammatory effects
Sinensetin Powder can inhibit the release of inflammatory factors (such as IL-6, IL-1β, and TNF-α), reducing inflammatory responses. In animal models, sweet orange flavonoids can significantly alleviate symptoms of inflammatory diseases such as colitis and periodontitis, and reduce tissue damage.
It indirectly exerts anti-inflammatory effects by regulating gut microbiota, increasing the abundance of beneficial bacteria and reducing harmful bacteria.
2. Antioxidant effects
It can effectively scavenge free radicals, reduce oxidative damage, and protect cells from oxidative stress.
By targeting the Bach1 protein, it promotes its ubiquitination and degradation, increases the expression of the antioxidant stress factor HO-1, and enhances cellular antioxidant capacity.
3. Cardiovascular protective effects
It may help lower blood pressure, improve vascular permeability, and reduce symptoms related to venous lymphatic insufficiency, such as leg heaviness and pain.
It has some potential role in the prevention of cardiovascular diseases, but more clinical studies are needed to verify this.
4. Neuroprotective potential
Some studies suggest that it may indirectly affect brain health and reduce the risk of depression by regulating the gut microbiota-brain axis, but its direct neuroprotective effects are not yet fully understood.
Application directions
Pharmaceuticals
Sinensetin Powder possesses anti-inflammatory, antioxidant, and immunomodulatory effects, and can be used for cardiovascular protection, with potential protective effects against neurodegenerative diseases such as Alzheimer's.
Food Industry
It can be used as a natural antioxidant to extend the shelf life of food products, in the development of functional foods, and to impart citrus flavor to food.
Cosmetics
It has whitening, anti-aging, and repairing and soothing effects, improving skin tone, reducing wrinkles, and strengthening the skin barrier.
Agriculture and Biotechnology
It can be used for plant protection, improving stress resistance, and regulating metabolic processes in microbial fermentation.
Company introduction and certificates obtained
Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
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