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Phellodendron Extract

Phellodendron Extract

Main ingredient: berberine
Source of extraction: dried bark of Phellodendron chinense or Phellodendron amurense of Rutaceae
Physical properties: brown powder
Nature and flavor: bitter, cold. Enters kidney and bladder meridians.
Delivery cycle:3-5 days
Sales group:not for individual customers
Inventory:In stock
Certificates:cGMP,FSSC2200,BRC,HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
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Product Introduction

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of phellodendron extract in China. With abundant experience, we warmly welcome you to wholesale bulk phellodendron extract for sale here from our factory. Quality products and reasonable price are available.

 

What is Phellodendron Extract?

 

Phellodendron Extract is extracted from the dried bark of the Rutaceae plant Phellodendron chinense or Phellodendron chinense. The former is commonly known as "Sichuan Phellodendron chinense" and the latter is commonly known as "Guan Phellodendron chinense". After peeling the bark, remove the rough skin and dry it in the sun. Phellodendron chinense Chemicalbook is also known as Huangbo, Yuanbo, Bomu, and Bopi. The main component is berberine. Used as a bittering agent. It has anti-microbial and protozoan, antihypertensive, anti-adrenaline-like effects, relaxes vascular smooth muscles, excites the uterus, bladder, bronchi, gastrointestinal tract, promotes bile and excites the cerebral cortex.
Phellodendron Extract,Sichuan Phellodendron chinense is plate-like or shallowly grooved, with varying lengths and widths, and a thickness of 3 to 6 mm. The outer surface is yellow-brown or yellow-brown, flat or with longitudinal grooves, and some have visible lenticel marks and residual gray-brown rough skin. The inner surface is dark yellow or light brown, with fine and dense longitudinal ridges. It is light, hard, fibrous in cross section, flaky and layered, and dark yellow. Slight smell, very bitter taste, sticky when chewed. Guan Huangbai Thickness 2-4mm. The outer surface is yellow-green or light brown-yellow, relatively flat, with irregular longitudinal cracks, small and rare lenticel marks, and occasionally grayish-white rough bark remains. The inner surface is yellow or yellow-brown. Light, hard, and bright yellow or yellow-green in cross section.

Chemical composition


Mainly contains berberine, and also contains palmitoyl tertrine, phellodendrine, jatrorrhizine, phellodendron, daurine, trichosanthesine, magnoline, limonin, etc.
Berberine: molecular formula [C20H18NO4]+, molecular weight 336.37, CAS number 2086-83-1, hydroxylate is yellow needle crystal (ether Chemicalbook), melting point 145℃, dihydrate of chloride is yellow crystal, slightly soluble in cold water, easily soluble in boiling water, almost insoluble in cold ethanol, chloroform and ether. Berberine has antimicrobial and protozoan, antihypertensive, anti-adrenaline-like effects, relaxes vascular smooth muscle, excites the uterus, bladder, bronchi, gastrointestinal tract, promotes bile secretion and excites the cerebral cortex.

 

Pharmacological effects


1. Antibacterial: The active antibacterial ingredient of Cortex Phellodendron is berberine. In vitro tests are effective against Staphylococcus aureus, pneumococci, Bacillus diphtheriae, viridans Streptococcus, Shigella dysenteriae (except Sonnei), etc. There are reports that it is effective against Escherichia coli and Pseudomonas aeruginosa.
2. Antifungal: Sichuan Phellodendron extract has inhibitory effects on Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum gypsum, and Microsporum woolly.
3. Antihypertensive effect: Cortex Phellodendri can produce significant and lasting antihypertensive effects when injected intravenously or intraperitoneally into anesthetized animals. Carotid artery injection is stronger than intravenous injection, so the antihypertensive effect may be central.
4. Anti-hepatitis: Huangbai decoction 6Chemicalbook.25%~100% in vitro test has inhibitory effect on hepatitis B antigen.
5. Anti-trichomoniasis: The 10% concentration of Cortex Phellodendron decoction and the 1:1 mixture culture of Trichomonas liquid can inhibit Trichomonas vaginalis.
6. Impact on immune function: Cortex Phellodendron decoction, 100% concentration, 0.3ml/animal gavage, for 7 consecutive days, can increase the number of spleen plaque-forming cells in mice.
7. Other effects: Phellodendron or ciclopirin has an inhibitory effect on the central nervous system, and the spontaneous activities and various reflexes of mice are inhibited; Phellodendron has a mild curare-like effect, which can cause tension in the rectus abdominis muscle of frogs. It has no effect but can inhibit the contractile response caused by acetylcholine.

Company Introduction And Certificates Obtained

 

YTBIO mainly supplies Phellodendron Extract etc. The company was established in 2014 and has many years of R&D and production experience. We are committed to the research and development, production and sales of raw materials for the 21st century health industry. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,etc. We always maintain the highest requirements for product quality.

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