4-butylresorcinol

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of 4-butylresorcinol in China. With abundant experience, we warmly welcome you to wholesale bulk 4-butylresorcinol for sale here from our factory. Quality products and reasonable price are available.

What is butylresorcinol?

4-Butylresorcinol, also known as Rucinol, is an active ingredient in various cosmetics, which can inhibit the production of melanin. Specifically, it can inhibit the two enzymes necessary for the production of melanin, namely tyrosine. acidase and 5,6-dihydroxyindole-2-carboxylic acid-oxidase.

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What are the benefits for the skin?

In the three processes of melanin source synthesis, 4-butylresorcinol not only has an important inhibitory effect on tyrosinase activity, but also has a synergistic effect on the whitening activity in the process.

Before melanin synthesis, it interferes with the synthesis and glycosylation of tyrosinase to prevent the enzyme from being absorbed by the melanosome.

During the synthesis of melanin, it inhibits the activity of enzymes and acts as a competitive inhibitor of tyrosinase and TRP1 enzymes, reducing the formation of by-products that promote melanin.

After the synthesis of melanin, it improves tyrosinase degradation,inhibits the transfer of melanosomes to keratinocytes, and has a light stripping effect due to the action of fatty acids. This function is enhanced by the presence of fatty acids and regulates the degradation of tyrosinase.

What are the application directions?

Mainly used in Cosmetics field. The main function is whitening and inhibiting melanin. It is an effective skin whitening and brightening agent

Adding amount: 0.1-0.3%

Whitening principle

The whitening principle embodied by 4-Butylresorcinol mainly focuses on the intracellular inhibition of melanocytes in the second major pathway. In addition, due to the small "stature", it is easy to penetrate into the skin and easily penetrate into the tyrosine. The active center of acidase, exerts a strong inhibitory activity.

POLA registered 4-butyl resorcinol as a whitening ingredient Rucinol as early as 1998.

Whitening data for 4-butylresorcinol

Kolbe et al. conducted a systematic comparative study on the whitening properties of hydroquinone, arbutin, kojic acid and 4-butylresorcinol, and tested the inhibitory effect of 4 whitening agents on human tyrosinase activity, as well as in The artificial skin model MelanoDerm inhibits melanin production. The experimental results show that 4-butylresorcinol is more than 6 times stronger than 377, 24 times stronger than kojic acid, and 310 times stronger than arbutin.

Experiments with artificial skin models were conducted using various inhibitors (4-butylresorcinol, kojic acid, arbutin, hydroquinone) at different concentrations. Determination of melanin content of skin models, data results are the average of 5 independent experiments

After all, there is still a certain gap between cell experiments and clinical applications, so the research team also organized clinical tests on 14 elderly volunteers (55-60 years old, female). A formulation containing 0.3% 4-butylresorcinol, 0.3% hexylresorcinol, and 0.5% phenethylresorcinol was used twice daily to treat senile plaques.

After 8 weeks, 4-butylresorcinol significantly reduced age spots, significantly better than hexylresorcinol and phenethylresorcinol.

Finally, here is an example of the effect of our laboratory internal test, using 2% 4-butylresorcinol whitening and lightening cream, morning and evening for 45 days, the effect is really amazing, the complexion is significantly improved every week Changes, even a few age spots have gradually faded away, leaving only a faint imprint.

Company introduction and certificates obtained

YTBIO mainly supplies herbal extracts, functional cosmetic raw materials, organic products, etc. The company was established in 2014 and has many years of R&D and production experience. We are committed to the research and development, production and sales of raw materials for the 21st century health industry. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA etc. We always maintain the highest requirements for product quality.

Our packaging

Our packing method is 1KG/Aluminium bags, 25kg/drum

For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin

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