Phytosphingosine

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of phytosphingosine in China. With abundant experience, we warmly welcome you to wholesale bulk phytosphingosine for sale here from our factory. Quality products and reasonable price are available.

Phytosphingosine is a precursor of ceramide and one of the lipid components of the skin. It has a natural barrier repair function. It also has a strong inhibitory effect on microbial activity and can inhibit harmful microorganisms such as Propionibacterium acnes, Staphylococcus aureus, and Malassezia. Phytosphingosine effectively fights inflammation and removes redness by inhibiting the synthesis of prostaglandins.
As one of the lipid components of the skin, phytosphingosine has multiple effects on the skin, adding points to high-end products such as anti-aging and repair.

With the increase of age, the PHS in human skin will gradually decrease, causing dry skin and rough skin. External use of phytosphingosine has the effect of effectively keeping the skin soft and protecting the skin layer. Add points to skin care products such as anti-aging and repair.

PHS has the effect of steroid antibiotics, but does not have the side effects of steroids and antibiotics. It is similar to the structure of the skin, increases the skin's own immune system, and has multiple physiological functions. It is particularly suitable for products such as fragile and sensitive skin, acne problem skin, and atopic dermatitis for young children.

Phytosphingosine is an octadecyl amino alcohol containing an unsaturated hydrocarbon chain. Sphingosine, which belongs to the sphingolipids, is one of the components of the cell membrane and a signaling lipid molecule that participates in a variety of cellular processes. Phytosphingosine is mainly distributed in seeds of plants such as wheat. Its content is extremely small and its extraction is extremely difficult. Moreover, phytosphingosine is based on a long chain of sphingomyelin that can serve as the backbone of ceramide (simply put, it is a naturally occurring ceramide precursor in the skin) and exists in the epidermis and the surface layer of the skin. It has a similar material structure to the stratum corneum and can quickly penetrate into the skin, combining with the water in the stratum corneum to form a mesh structure that locks in moisture.

Skin barrier function
The skin barrier function is located in the outermost layer of the epidermis, the stratum corneum (SC), which is composed of keratinocytes and intercellular lipid lamellar tissue.

The formation of normal keratinocytes requires two independent processes: first, the maturation of the cornified envelope (CE), which is cross-linked by transglutaminase-1 (TGase-1) and covalently formed into the corneocyte lipid membrane (CLE) by ω-hydroxyceramide. Second, the anucleated keratinocytes are flattened by the compression of filaggrin (FLG) and filled with natural moisturizing factors.

PHS increases the expression of TGase-1 and FLG genes in human epidermal keratinocytes

PHS improves the expression of FLG in a three-dimensional human skin equivalent model

02 Moisturizing and nourishing

Topical application of PHS solution can improve the moisturizing function of human skin

03 Scalp Care

PHS can balance the hair growth cycle and prevent hair loss

PHS can effectively improve hair quality and scalp health

04 Whitening and dark circles removal

05 Anti-inflammatory and antibacterial 

06 Treatment of acne and ulcers 

07 Oral Care 

Note: All of the above are experimental mouthwashes. () are the main ingredients of the mouthwash

PS (phytosphingosine); CR (dichlorphenamine); NS (xylitol); HM (cetylpyridinium chloride); CK (cetylpyridinium chloride)

The BioFlux system tested the anti-adhesive and biofilm-inhibiting effects of PHS under dynamic conditions

Over time, adherent cells accumulated and formed more complex biofilms. However, on the PHS-treated surface, almost no bacterial adhesion was observed within 16 hours.

Effect of PHS on enamel surface loss and surface microhardness of enamel specimens

As shown, artificial saliva protects teeth better than remineralizing solutions
PHS can protect enamel specimens from tissue damage. The highly positively charged PHS has a high affinity for negatively charged surfaces and ions (enamel), forming a tiny protective layer.
The surface microhardness of PHS-treated enamel was significantly increased compared with the control group (P=0.007)

08 Anti-aging and anti-wrinkle

YTBIO mainly supplies Pure Liposomal Vitamin C powder etc. The company was established in 2014 and has many years of R&D and production experience. We are committed to the research and development, production and sales of raw materials for the 21st century health industry. The certificates obtained so far include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,etc. We always maintain the highest requirements for product quality.

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