Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of acetyl heptapeptide-4 in China. With abundant experience, we warmly welcome you to wholesale bulk acetyl heptapeptide-4 for sale here from our factory. Quality products and reasonable price are available.
Introduction to Acetyl Heptapeptide-4
YTBIO's Acetyl Heptapeptide-4 (98%) is a high-purity cosmetic active peptide ingredient produced using advanced biosynthetic technology. It offers excellent compatibility and is suitable for use in skincare products designed for anti-aging, moisturizing, and skin repair.
Acetyl Heptapeptide 4 is an active cosmetic peptide frequently used in high-end skincare products as a probiotic-inspired ingredient. Its molecular structure consists of seven amino acids, and it is modified via acetylation to enhance stability and transdermal absorption. It strengthens the skin barrier by promoting microbial balance and diversity and increasing beneficial bacteria, thereby boosting the skin's natural defense system.
Product details
|
INCI Name |
Acetyl Heptapeptide-4 |
|
|
Batch No. |
20250924-0 |
|
|
Manufacturing Date |
Sep,24, 2025 |
|
|
Storage |
Keep in dark and cool dry place (-20 to 8° C) |
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| Expiry Date | Sep,23, 2027 |
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Items |
Standards |
Results |
|
Appearance |
White to off-white powder |
Complies |
|
Identity by ESI-MS |
Theoretical MW:960.07 |
Complies |
|
Purity (HPLC) |
≥98.0% |
98.65% |
|
Water (K.F.) |
≤7.0% |
2.77% |
|
Acetic acid content |
≤20.0% |
3.50% |
|
Conclusion |
Conforms to standard |
Complies |
Mechanism of action



① Microbial Barrier
It promotes the balance and diversity of the skin microbiota and increases the proportion of beneficial bacteria, thereby helping to activate the skin's innate defense system. Rather than directly applying live bacteria to the face, it fosters a more favorable environment for beneficial bacteria to thrive.
② Physical Barrier
It has been observed to enhance corneocyte cohesion and reduce skin scaling. It provides a barrier-protective effect, helping to minimize transepidermal water loss (TEWL) and prevent dryness.
③ Immune / Anti-inflammatory
In vitro studies demonstrate that it inhibits the activation of Kallikrein-5 (KLK5, a serine protease) and PAR-2. The overactivation of PAR-2 by KLK5 is a key factor in triggering inflammation and itching, as well as compromising the skin barrier; Acetyl Heptapeptide-4 helps alleviate inflammation and itching, and is also effective in reducing scalp inflammation, itching, and flaking.
Applications and Precautions
It is particularly suitable for skincare products designed for sensitive skin, offering rapid relief from redness and discomfort. It can be incorporated into any formulation to strengthen the skin barrier and prevent dehydration.
Storage Conditions
Store in a sealed container, protected from light, in a dry place at 2–8°C. For long-term storage, freezing at -15 to -20°C is recommended.
Formulation Recommendations: It is often paired with barrier-repairing ingredients (such as ceramides, cholesterol, and panthenol) and prebiotics/postbiotics (such as inulin and alpha-glucan oligosaccharides) to nourish the skin microbiome and support barrier repair.
Safety: Acetyl Heptapeptide-4 is suitable for long-term, regular skincare use. It is generally considered to have good tolerability, though individual responses may vary.
Is a higher concentration always better?
It is an ingredient that is effective at low dosages; "low" does not mean ineffective, nor does "high" necessarily mean better. The optimal concentration depends on the product positioning and the overall formulation.
Can it cure eczema or dandruff?
While the mechanisms involved are indeed related to these issues, it is a cosmetic ingredient designed to soothe and protect the skin, not a pharmaceutical drug. It cannot cure skin diseases; please consult a medical professional if you have a diagnosed skin condition.

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contact us
Are you looking for a reliable supplier of peptide raw materials for skincare products?YTBIO provides high-quality Acetyl Heptapeptide-4 (98% purity) and related services.Contact us now for samples, technical information, and customized quotes.
Telephone/WhatsApp:+8617782577059
Email:sales@sxytbio.com
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