Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of genipin in China. With abundant experience, we warmly welcome you to wholesale bulk genipin for sale here from our factory. Quality products and reasonable price are available.

Product Description

Genipin, the product of geniposide hydrolyzed by -glucosidase, is an excellent natural biological cross-linking agent. It can be cross-linked with protein, collagen, gelatin, chitosan and other biological materials, such as artificial bone, wound dressing materials, etc., and its toxicity is far lower than glutaraldehyde and other commonly used chemical cross-linking agents. It can also be used to treat liver diseases, hypotension, constipation and so on.

Genipin is the product of hydrolysis of β-glucosidase by β-glucosidase. It is an excellent natural biological cross-linking agent that can make biomass materials such as protein, collagen, gelatin, and chitosan. For example, artificial bones, wound bandaging materials, etc., the toxicity is far lower than that of martyldehyde and other commonly used chemical cross -linking agents. It can also be used to treat liver disease, antihypertensive, laxative, etc. The preparation method of Jingniping generally uses the extract of Jingnipidoside from the gardenia, and then hydrolyze with β -glucosidase, and then uses ether extraction, vacuum concentration, and heavy crystallization. Microbial transformation can be used. The content of Jingnipin is high in eucommia and gardenia, reaching about 3-8%. However, because the cultivation of gardenia is easy to cultivate and large output, Jingniping's production mainly uses gardenia as raw materials.

Test report

ITEM	STANDARD	TEST RESULT	TEST METHORD
Genipin	≥98.0%	98.62%	HPLC
Physical & Chemical
Appearance	White powder or crystals	Complies	Visual
Odor & Taste	Characteristic	Characteristic	Organoleptic
Particle Size	98% through 100mesh	Complies	USP<786>
Loss on drying	≤2.0%	0.35%	USP <731>
Ash	≤1.0%	0.12%	USP <281>
Solvents Residue	Meet USP standard	Complies	USP <476>
Pesticide Residue	Negative	Complies	USP <561>
Heavy Metal
Total Heavy Metal	≤10.0ppm	Complies	ICP-MS
As	≤0.5ppm	0.28ppm	ICP-MS
Pb	≤0.5ppm	0.06ppm	ICP-MS
Microbiological Test
Total Plate Count	≤1000cfu/g	320cfu/g	AOAC
Mold and Yeast	≤100cfu/g	35cfu/g	AOAC
E.Coli	Negative	Complies	AOAC
Salmonella	Negative	Complies	AOAC
Conclusion	Conform with specification,Non-irradiation, Allergen Free, BSE/TSE Free
Storage	Store in cool and dry places. Keep away from strong light and heat
Packing	By 100gram/package, 1000gram/package
Shelf Life	24 months under the above condition,and in it’s original package

Source

Genipin Source

Molecular Structure

Genipin

What are the benefits of Genipin ?

1. The liver and gallbladder effect is that Jingniping can stimulate multi -drug resistance protein (MRP2) inserting bile small tubular membranes, and bile secretion is caused by increasing bile excreted glutathione. Masaki et al. "Study Jingniping's bile effects, and found that Jingniping can increase the content of glutathione in bile flow and bile excretion, and will not be suppressed by autumn water fairy.

2. Anti -inflammatory effects have long known that gardenia fruits have anti -inflammatory activity, but they do not know its anti -inflammatory mechanism. The effects of gardenin, gardenia glycolic acid, Jingniping, and tiblisa have the effects of prostaglandin and NO, thereby establishing anti -inflammatory and cell mechanisms of cabinet fruits. It is speculated that Jingniping is an anti -inflammatory active substance in gardenia fruits, which can inhibit the production of prostaglandins and NO

3. Anticarnic effect, the thrombosis model induced by the optical reaction of the optical chemical reactions forms the effect of antiphaitic thrombosis, and studies its in vitro antiplatelet condensate.

4. Treatment of diabetes, examined gardenia extracts, and found that Jingniping was active substance for treating type 2 diabetes in gardenia. The linked protein can negatively adjust the secretion of insulin by regulating the mitochondrial proton leakage.

5. Because it can inhibit the calcium ion carrier in the nerve-2A cells, A23187-induced, which is induced by the protease 3/7 and the internal quality network stress, it is speculated that it can prevent and control Alde Nervous degenerative diseases such as Hemimer's disease and Parkinson's disease.

6.Genipin is the active compound found in the fruit of Gardenia jasminoides Ellis extract used as a Chinese traditional medicine to relieve the symptoms of type 2 diabetes.

7. It is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking.

It has a low acute toxicity; much less toxic than glutaraldehyde and many other commonly used synthetic cross-linking reagents. It is also used for pharmaceutical purposes, such as choleretic action for liver diseases control.

8. Furthermore, genipin can be used as a cross-linking agent for immobilized enzymes, as a regulating agent for drug delivery, as the raw material for gardenia blue pigment preparation, and as the intermediate for alkaloid syntheses.

Product Application

1. Apply to the field of food; increase nutritional value.

2. Apply to the field of health products; you can fill in capsules and press tablets.

3. Apply to the field of drugs. To protect the liver, reduce blood pressure, etc.

We support for buyers:

* Sample is available upon the buyer requirements to test
* Detection by third party
* Document set
* Fast delivery
* After service
* Visit the factory

Company introduction and certificates obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

Certificate