Epicatechin Powder

As a flavonoid substance, epicatechin has many physiological activities, such as anti-oxidation, lipid-lowering and blood sugar-lowering, cardiovascular disease prevention, anti-inflammatory, nerve protection, antibacterial and other effects.
Antioxidant effect
When the concentration of free radicals in the body is too high, the risk of disease will increase. The antioxidant activity of epicatechin is believed to be the ability to capture chain-carrying free radicals by providing phenolic hydrogen atoms in the A ring and the B ring. Due to the presence of phenolic hydroxyl groups in the molecular structure of epicatechin, especially the ortho-hydroxyl groups in catechol or pyrogallol, it is easy to be oxidized to quinone structures, which makes it have a strong ability to capture free radicals such as active oxygen, and thus has the function of efficiently scavenging free radicals and lipid free radicals.
Reduce lipids and blood sugar and reduce insulin resistance
Obese individuals often induce the occurrence of chronic diseases such as diabetes. BETTAIEB et al. found that adding 20 mg/kg body weight of epicatechin to the diet of adult rats on a high-fructose diet can reduce the damage of the insulin signaling cascade (IR, IRK-1, Akt, ERK1/2), and reduce the upregulation of negative regulators (PKC, IKK, JNK and PTP1B) in rat adipose tissue, indicating that epicatechin alleviates insulin resistance through its redox regulation mechanism.
Prevention of cardiovascular disease
Compared with the control group of mice on a high-cholesterol diet, the area of ​​atherosclerotic lesions in the epicatechin-added group of mice was reduced by 27%, and the formation of plasma SAA and human-CRP induced by the diet was inhibited, and there was no effect on plasma lipids. At the same time, the anti-atherogenic effect of epicatechin is specific to severe injury types and has almost no effect on mild injuries, which indicates that epicatechin tends to alleviate severe cardiovascular lesions.