Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of celastrol powder in China. With abundant experience, we warmly welcome you to wholesale bulk celastrol powder for sale here from our factory. Quality products and reasonable price are available.
About The Detailed Introduction Of Celastrol?
Celastrol is a chemical substance, a natural product with various biological activities, derived from the root bark of the traditional Chinese medicine Tripterygium wilfordii, and its molecular formula is C29H38O4.
Celastrol powder is derived from the root bark of the traditional Chinese medicine Tripterygium wilfordii (scientific name: Tripterygium wilfordii Hook. f.). It is one of the active ingredients in preparations such as Tripterygium tablets and Tripterygium polyglycoside tablets for treating rheumatoid disease. Modern pharmacological research shows that triptolide is a natural product with a variety of strong biological activities, such as it has strong antioxidant effects, anti-rheumatoid effects, etc. In recent years, triptolide has been widely used in Its unique effect in weight loss has attracted the attention of researchers at home and abroad.
Celastrol belongs to the triterpene class of compounds, and its chemical structure includes a tricyclic framework and multiple side chains. In the structure of triptolide, there is a part called the triterpene bridge, which is a key part of the substance's interaction with other components and affecting its biological activity.
Product details list
| CAS | 34157-83-0 |
| Molecular formula | C29H38O4 |
| Molecular weight | 450.61 |
| EINECS | 636-472-5 |
| Melting point | 219-230°C |
| Boiling point | 645.7±55.0°C(Predicted) |
| Density | 1.2 |
| Solubility | DMSO:>10mg/mL |
| Acidity coefficient (pKa) | 4.78±0.70 (Predicted) |
What Are The Benefits?
Anti-inflammatory effect: Celastrol Powder has significant anti-inflammatory effect. It can inhibit the occurrence and development of inflammatory reactions and reduce pain, swelling and other symptoms caused by inflammation. It exerts anti-inflammatory effects by inhibiting the activation of inflammatory cells, inhibiting the release of inflammatory mediators, and regulating the immune system. It has a certain therapeutic effect on inflammatory diseases such as rheumatoid arthritis and rheumatoid arthritis.
Immunomodulatory effect: It has a regulatory effect on the immune system. It can regulate the number and activity of immune cells and enhance the body's immunity. At the same time, it can also suppress excessive immune responses and reduce the symptoms of autoimmune diseases, such as rheumatoid arthritis, autoimmune liver disease, etc.
Antioxidant effect: It has a certain antioxidant effect, which can remove free radicals in the body and reduce the damage of cells and tissues caused by oxidative stress. This is of great significance for the prevention and treatment of many chronic diseases, such as cardiovascular diseases, neurological diseases and Alzheimer's disease.
Blood pressure lowering effect: It has the effect of lowering blood pressure. It can reduce blood circulation resistance and relieve symptoms caused by high blood pressure by dilating blood vessels and inhibiting the release of vasoconstrictor substances.
Anti-fibrosis effect: It can inhibit the occurrence and development of pathological fibrosis and reduce the formation of scar tissue. It has certain potential in treating liver cirrhosis, renal fibrosis and other diseases.
Improve immune hepatitis: It can reduce liver inflammation and damage caused by immune hepatitis, and has certain antiviral effects.
Anti-platelet aggregation effect: It can inhibit platelet aggregation and thrombosis, and has certain positive significance in preventing cardiovascular and cerebrovascular diseases.
On May 11, 2015, Umut Ozcan’s team at Harvard Medical School published a blockbuster research result in the journal Cell. When they screened more than 1,000 compounds that could reduce endoplasmic reticulum stress, they found that triptolide had good biological activity. They used it to treat obese mice. Within a week, the food intake of obese mice decreased. By the end of the third week, obese mice treated with triptolide had lost 45% of their weight compared to untreated obese mice! The study also showed that triptolide may have therapeutic effects on diseases such as type 2 diabetes and fatty liver. It was the first time that triptolide was discovered to be an effective substance that can significantly prevent and reverse obesity in mice.
As a weight-loss drug, triptolide works almost perfectly in mice. Its function is to increase the sensitivity of leptin, which can not only reduce the desire to eat, reduce energy intake, but also accelerate fat consumption. In a state of hunger, its effect will disappear, causing leptin to return to normal levels without affecting eating; in addition, triptolide only targets adipose tissue and will not affect lean body mass (weight other than fat), which is related to hunger. The resulting weight loss effects vary widely. These characteristics make it the most potential weight loss drug.
What Are The Application Directions?
Field of Traditional Chinese Medicine: Celastrol powder is one of the main active ingredients of the traditional Chinese medicine Tripterygium wilfordii and is widely used in the field of Traditional Chinese Medicine. Tripterygium wilfordii is a traditional Chinese medicine commonly used to treat inflammatory diseases such as rheumatoid arthritis and rheumatoid arthritis. Tripterine has significant anti-inflammatory and immunomodulatory effects, and can help patients relieve diseases by reducing symptoms and improving joint function.
Autoimmune disease treatment field: It has a certain therapeutic effect on autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, etc. It can regulate the number and activity of immune cells, suppress excessive immune responses, and reduce the symptoms of diseases.
Treatment field of cardiovascular and cerebrovascular diseases: It has the effect of lowering blood pressure and anti-platelet aggregation, and can be used as an auxiliary treatment for cardiovascular and cerebrovascular diseases. It can dilate blood vessels, reduce blood circulation resistance, reduce the formation of thrombus, and has certain positive significance in the prevention and treatment of hypertension, coronary heart disease, stroke and other diseases.
Antioxidant and anti-aging fields: It has a certain antioxidant effect, which can remove free radicals in the body and reduce the damage of cells and tissues caused by oxidative stress. Therefore, it also has application value in the fields of anti-aging and health care.
Liver disease treatment: Tripterine can be used to treat liver diseases such as cirrhosis and hepatitis, and has the effect of improving liver function and anti-fibrosis.
Company Introduction And Certificates Obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Celastrol Powder etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
Our Packaging
Our Team
Factory
Payment Method
Shipping Method
Hot Tags: celastrol powder, China celastrol powder manufacturers, suppliers, factory
