Pure Nicotinic Acid

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of pure nicotinic acid in China. With abundant experience, we warmly welcome you to wholesale bulk pure nicotinic acid for sale here from our factory. Quality products and reasonable price are available.

Pure Nicotinic acid, also known as vitamin B3, mainly exists in animal organs, muscle tissue, and also exists in trace amounts in fruits and egg yolks. It is one of the 13 essential vitamins for the human body. It belongs to the B vitamins, is heat-resistant, can sublimate, and is a water-soluble Sex vitamins. Niacin can be converted into nicotinamide in the human body and participates in the synthesis of coenzyme I and coenzyme II. It plays an important role in lipid metabolism in the body, oxidation of tissue respiration, and anaerobic decomposition of sugars.

At present, niacin is mainly used as a feed additive, which can improve the utilization rate of feed protein, increase the milk production of dairy cows, and the output and quality of fish, chicken, duck, cattle, sheep and other poultry and livestock meat. Niacin is also a widely used pharmaceutical intermediate. It can be used as raw material to synthesize a variety of medicines, such as nicotinic acid inositol ester and nicotinate. In addition, nicotinic acid also plays an irreplaceable role in the fields of luminescent materials, dyes, and electroplating industries.

Nicotinic acid, also known as vitamin PP, is heat-resistant and capable of sublimation. First described in 1873 by Hugo Weidel in his research on nicotine. It is one of the 13 essential vitamins for the human body. It is a water-soluble vitamin and belongs to the vitamin B family. Niacin is converted into nicotinamide in the human body. Niacinamide is a component of coenzyme I and coenzyme II. It participates in lipid metabolism in the body, the oxidation process of tissue respiration and the anaerobic decomposition of sugars.
Niacin and niacinamide are two components of vitamin B3, they can be transformed into each other, that is, niacin can be converted into niacinamide in the human body, and niacinamide can be decomposed into niacin in the body, complementing each other.

Product Details List

Constitute nicotinamide adenine dinucleotide (coenzyme I, NAD+ or CoI) and nicotinamide adenine dinucleotide phosphate (coenzyme 11, NADP+ or CoII) nicotinamide combines with adenine, ribose and phosphoric acid in vivo to form nicotinamide Adenine dinucleotide and nicotinamide adenine dinucleotide phosphate act as electron carriers or hydrogen transferors in biological redox reactions, depending on the molecular structure of nicotinamide. The nicotinamide pyridine ring has the characteristics of reversible hydrogenation and electron addition and dehydrogenation and deelectronization, and can transfer hydrogen and transfer electrons during the enzymatic reaction process. Glucose tolerance factor (GTF) is a complex composed of trivalent chromium, niacin, and glutathione. It is an insulin cofactor that increases glucose utilization and promotes the conversion of glucose into fat. Niacin can reduce blood cholesterol, triglyceride and beta-lipoprotein concentrations and dilate blood vessels.

Niacin exists in food in the form of coenzyme, after digestion, it is absorbed in the small intestine of the stomach, enters the liver in the form of niacin through the portal vein, and is converted into NAD+ and NADP+. The unmetabolized nicotinic acid and nicotinamide in the liver flow into other tissues with the blood, and then form the coenzyme containing nicotinic acid. The kidneys convert niacinamide directly to NADP+. Most of the excess niacin is excreted from urine through methylation, and its excretion form is N1-methylnicotinamide and N1-methyl-2-pyridone-5-carboxamide (2-pyridone for short). The excretion of N1-methylnicotinamide in normal human urine is 7.5mg/d, equivalent to 15% of the intake. Niacin is also excreted with milk secretion and sweat.

Energy metabolism: It is one of the key components of energy metabolism. It participates in the synthesis and release of energy in the body, helping to convert fat, carbohydrates and proteins into energy and maintaining normal metabolic activities of the body.

Cardiovascular Health: Helps promote a healthy cardiovascular system. It can increase levels of HDL cholesterol (good cholesterol) and lower levels of LDL cholesterol (bad cholesterol), thereby reducing the risk of cardiovascular disease.

Blood Circulation: Helps promote blood circulation. It dilates blood vessels, increases blood flow, and reduces blood viscosity. This helps improve blood supply and alleviate circulation problems such as arteriosclerosis and high blood pressure.

Cranial nerve function: It plays an important role in the health of the nervous system and brain function. It can provide the energy needed by brain cells, promote the synthesis and release of neurotransmitters, and maintain the normal neurotransmission process. In addition, niacin is also associated with the repair and protection of cellular DNA, helping to prevent damage and aging of brain cells.

Skin Health: It is also good for skin health. It can promote the metabolism of skin cells, improve the water retention capacity of the skin, and improve the elasticity and luster of the skin. In addition, it can also reduce skin inflammation and excessive shedding of the stratum corneum, helping to improve skin problems such as acne and eczema.

Digestive health: It also plays an important role in the health of the digestive system. It can promote the cell proliferation and repair of gastrointestinal mucosa and protect the integrity of gastrointestinal tissue. In addition, it can also promote the secretion of gastric acid and pepsin, and promote food digestion and absorption.

Antioxidant effect: It has certain antioxidant effect. It neutralizes free radicals and reduces oxidative stress damage to the body. Antioxidants help slow down the aging process, protect cells from oxidative damage, and reduce the risk of disease.

Pure Nicotinic acid has three product specifications, namely food grade, feed grade and pharmaceutical grade. Niacin is mainly used as a nutritional additive (water-soluble vitamin) in feed, and is also used as an intermediate in food, medicine, and dyes. It is also used as an additive in electroplating solutions and as a biochemical reagent.

Application of Pure Nicotinic acid in the field of pharmaceutical synthesis
As a medicine, niacin can prevent and treat skin diseases and similar vitamin deficiencies. It has the effect of dilating blood vessels and is used to treat peripheral nerve spasm, arteriosclerosis and other diseases. Niacin can also be used as a pharmaceutical intermediate for the synthesis of a variety of amide and ester drugs with important medical uses. For example, nicotinamide can be used to treat gastrointestinal diseases, and nicotinic acid hydroxymethylamine is a good medicine that protects the liver, promotes choleresis, and inhibits bacteria. As a highly effective molluscicide, nicotinamide can be used to prevent and treat schistosomiasis; niacin and tromethamine can be synthesized to treat circulatory system disorders, vitamin B deficiency, glossitis, hypertension and other diseases; niacin Nicothamide synthesized with diethylamine is a central nervous system stimulant, used to treat central nervous system respiratory and circulatory system failure; nicotinic acid inositol ester and nicotine, which are produced by the reaction of nicotinic acid and alcohol, are used to treat hyperlipidemia. disease, coronary heart disease, migraine, peripheral vascular disorders, etc.

Application of nicotinic acid as an auxiliary agent
Niacin is an indispensable food and feed additive for the growth and development of humans and animals. Therefore, niacin is widely used as an additive in cakes, dairy products, corn flour, etc.; niacin can also be used in combination with vitamins to replace part of nitrite as a deodorant or preservative for meat products. In addition, niacin can also As a preservative for vegetables. Since a large part of niacin in grain feeds exists in complex form and cannot be directly absorbed by animals, a commonly used method in the world is to add synthetic niacin into feeds. Feeding experiments have proven that synthetic niacin can be 100% absorbed and utilized by animals, and can achieve significant weight gain in a short period of time. According to the situation of my country's breeding industry, the standard for adding niacin in my country is: 9-24 mg per kg of pig feed (dry basis), and 10-27 mg per kg of chicken feed (dry basis).

food additives
Niacin belongs to the vitamin B family and participates in the body's lipid metabolism, oxidation process and anaerobic decomposition process. Niacin can be converted into tryptophan in the body. The human body is generally not prone to niacin deficiency. However, when the staple food does not contain niacin, or there are substances that decompose niacin in the staple food, it is easy to cause niacin deficiency. Coarse skin disease. Therefore, niacin is widely used in pasta processing, dairy products and corn flour production. Adding a certain amount of niacin to food can effectively prevent the occurrence of such deficiencies.

Feed additives
Niacin is an indispensable substance for animal growth and development. Niacin in cereal feeds mainly exists in a bound form, which is difficult for animals to absorb. Therefore, synthetic niacin needs to be artificially added to the feed.
Adding an appropriate amount of niacin to the feed and feeding piglets (chickens) can quickly increase their weight. Feeding laying hens niacin-based feed can increase their egg production rate, and the eggs also contain a certain amount of niacin, which improves their nutritional value.

reactive dyes
Because niacin can make fiber dyeing durable, has a wide range of applications, and has good uniformity, niacin has outstanding performance in the dye industry and has become an intermediate for a variety of reactive dyes. In 1984, Nippon Chemical Company launched a weakly alkaline nicotinic acid triazine reactive dye.

Daily chemicals and industrial products
In the daily chemical industry, nicotinic acid can be formulated with other daily chemical raw materials to form products with excellent performance, such as hair dye auxiliaries, detergents, etc.

other apps
Niacin is an important chemical additive and corrosion inhibitor, and can be used as an antioxidant and anti-fogging agent in photosensitive materials. Niacin is also an excellent brightening additive during electroplating. As long as 1-10g of nicotinic acid is added to each liter of electroplating solution, it will have a significant effect.

Pure Nicotinic acid is used as an antioxidant and anti-fog agent in photosensitive materials. Adding 0.1% niacin aqueous solution to the photosensitive emulsion can increase the stability of the photosensitive material to light; adding 5-20mL of 0.1% niacin aqueous solution to each milliliter of the photosensitive emulsion can reduce the fog of the photosensitive material.

Company introduction and certificates obtained

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Pure Nicotinic acid etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,  and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

For more information about Pure Nicotinic Acid or other products, please contact:

Email: sales@sxytbio.com
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