Modified Citrus Pectin

Modified citrus pectin powder (MCP) is a low-molecular-weight, water-soluble cellulose polysaccharide obtained from the peels and pods of citrus fruits (mandarins, lemons, oranges, grapefruits, etc.) through enzymatic hydrolysis of natural citrus pectin. Its molecular weight ranges from 5000-35000 Da (typical specification 5000-22000 Da), with an esterification degree of 2%-30%. Compared to ordinary pectin, the hydrolysis process significantly reduces both the molecular weight and the degree of esterification, allowing MCP to penetrate the intestinal wall and enter the bloodstream, while ordinary pectin only functions as dietary fiber in the intestines.

MCP can significantly improve appetite, enhance immune function, regulate immune disorders, lower cholesterol to prevent atherosclerosis, lower blood lipids and blood sugar, and treat and prevent obesity-related fatty liver. Therefore, MCP can be used in immune-enhancing drugs, functional foods, dietary supplements, and heavy metal detoxification products.

YTBIO supplies modified citrus pectin with molecular weights ranging from 5000 to 22000 Da. The molecular weight distribution between batches is controllable, and it has good water solubility. It is suitable for dosage forms such as oral liquids, solid beverages, and capsules. Customized molecular weight specifications are supported. It has complete certifications and flexible delivery.

Immune Regulation

This component helps the body maintain a basic immune response, enhances the activity of certain immune cells, and assists the body in defense.

Metabolic Health Support

Studies have shown that MCP may help regulate blood lipids and blood sugar.

Detoxification

The molecular structure of MCP may help bind to and promote the excretion of heavy metals (such as lead) from the body.

Gut Health

As a soluble dietary fiber, MCP can increase stool volume and promote intestinal peristalsis, which can help relieve constipation.

Food Industry (Main)

Emulsification and Stabilization: Widely used as an emulsifier in dairy products, beverages, and sauces to improve product taste and texture.

Thickening and Gel Properties: Adjusts the viscosity of food products, suitable for jellies, jams, and candies.

Cosmetics and Personal Care

Moisturizing and Anti-aging: Provides moisturizing effects, helping skin retain moisture and reduce fine lines. Can also be used with antioxidants to slow down the skin aging process.

Hair Care Applications: Added to conditioners or hair masks to enhance hair shine and smoothness.

Pharmaceuticals

Drug Delivery Carrier: Chemically modified to enable targeted drug release in the colon, avoiding drug breakdown in the stomach and improving absorption efficiency.

Wound Healing Promotion: Can be formulated into hydrogels or films to accelerate wound healing, reduce local inflammation, and promote tissue regeneration.

Modified citrus pectin is a safe ingredient recommended by the FAQ and WHO, with no limit on the daily intake of the human body. The company uses a 100,000-level GMP workshop and imported lemon peels, adopts bioenzymatic hydrolysis technology to extract MCP, strictly controls the raw materials and production process, and does not add any non-imported chemical raw materials.

YTBIO small molecule citrus pectin series products are functional foods with high safety, suitable for health care of the general population, and also suitable for patients with high or high blood pressure.

Does MCP have any side effects?

MCP does not directly kill cancer cells, but prevents tumor cells from clumping, vascular adhesion and nutrient absorption through chelation with galectin-3. It does not have any clinical toxic side effects. Individual patients may experience loose stools and increased frequency, but without any pain or other discomfort. It is a highly safe functional food.

What is the mechanism of MCP beauty treatment?

MCP is a soluble dietary fiber. Due to its low calorie content and strong satiety, the weight loss effect of dietary fiber has been recognized by many nutritionists; MCP's high water absorption and good film-forming properties are perfectly combined, which can provide It provides a good moisturizing effect on the skin; MCP's chelation of heavy metals and antioxidant effects detoxify the human body and promote metabolism, and has the effect of preventing acne and chloasma; MCP can absorb intestinal toxins and play an anti-inflammatory role. Aging function; MCP has anticoagulant and thrombolytic effects, can reduce the level of fibrin in blood vessels, unblock blood vessels, accelerate nutrients into the skin with microcirculation, thereby improving skin metabolism; MCP can absorb cholesterol and take it out In vitro, reducing the concentration of cholesterol in the blood is beneficial to maintaining the function of the cardiovascular system, making blood vessels elastic, and ensuring the normal supply of skin nutrients; MCP helps to produce various cell growth factors and repair skin tissue by activating cell growth factors; The antioxidant mechanism of MCP and its ability to absorb ultraviolet rays make it have good anti-aging and whitening effects; the antibacterial effect of MCP makes it effective in removing acne.

What is the mechanism of MCP reducing three highs?

Lowering blood lipids: MCP has characteristics such as water holding capacity and macromolecular structure. The spatial molecular structure presented after absorbing water absorbs water and expands in the upper gastrointestinal tract, which has a filling effect on the intestines, can increase the feeling of satiety, and delay gastric emptying time, thus Influences hormone secretion in response to meals, affects food intake, and reduces fat and energy intake. At the same time, the adsorption of MCP can reduce the absorption rate of dietary cholesterol; MCP is highly viscous, and its physical barrier function reduces the absorption rate of cholesterol; MCP can scavenge free radicals in the body and reduce lipid peroxidation of cell membranes to achieve the purpose of lowering blood lipids.

Lowering blood sugar: MCP can delay the absorption of sugars and lipids in the intestine; the short-chain fatty acids produced by fermentation in the intestine have the effect of regulating hormones, and can promote the production of hypoglycemic hormones. When MCP exerts its hypoglycemic effect, it does not increase the secretion of insulin, but acts on the enzymes of glucose metabolism. By regulating the activity of glucose metabolism-related enzymes, it promotes the utilization of glucose and inhibits gluconeogenesis, thereby improving glucose metabolism disorders and insulin resistance. And achieve the purpose of lowering blood sugar.

Lowering blood pressure: MCP can absorb sodium-containing compounds in the body and excrete them from the body at the same time, reducing the absorption rate of salt, thereby helping to lower blood pressure; MCP can accelerate the conversion and excretion of cholesterol through a variety of mechanisms, thereby preventing and treating hyperlipidemia. It causes arteriosclerosis and hypertension; MCP can reduce the content of angiotensin II and endothelin in plasma, thereby lowering blood pressure; MCP can not only directly regulate blood pressure through its vasodilatory effect, but also protect vascular endothelial cells and inhibit smooth muscle. Cell proliferation, regulating platelet aggregation, affecting myocardial contractile function and myocardial cell apoptosis are important factors in the course of cardiovascular disease and hypertension, and are considered to play a major protective role; MCP can reduce the risk of hypertension in patients with hypertension. arterial systolic blood pressure; MCP can affect cardiovascular activity by weakening the excitability of the sympathetic nervous system through central or peripheral pathways.

What is the mechanism by which MCP improves gastrointestinal tract and constipation?

MCP contains a large amount of water-soluble dietary fiber, which can promote gastrointestinal peristalsis and improve gastrointestinal function; MCP has strong water-holding properties and can absorb more than 20 times its mass of water, which can prevent stool from drying out in the intestine and cause constipation. It has the effect of preventing constipation; the gel properties of MCP enable it to change the absorption ratio of nutrients in the body, adsorb and eliminate toxins in the body, prevent diarrhea caused by pathogenic factors, and prevent diarrhea; the film-forming properties of MCP make It forms a polymer film distributed on the stomach wall to prevent damage to the gastric mucosa and intestinal mucosa, prevent further deterioration of enteritis, gastric ulcer, etc., and protect the recovery of damaged mucosa; MCP has chelating properties and is effective against lead, cadmium Heavy metals such as arsenic and arsenic have a good chelating effect, which can effectively prevent these heavy metals from damaging the body, improve the body's immunity, and prevent the gastrointestinal tract from causing diarrhea, flatulence, constipation and other diseases due to the reduction of the immune system; the microbial degradation properties of MCP It can promote the large-scale reproduction of beneficial bacteria, maintain the dominance of beneficial bacteria in the intestines, and reduce the chance of gastrointestinal diseases.

What is the mechanism by which MCP discharges lead and heavy metals?

Animal experiments at Zhejiang University have proven that small molecule pectin can chelate heavy metals and has a good lead removal effect. It is worth mentioning that the chelation effect of MCP is selective and only excludes heavy metals such as lead, cadmium, and arsenic that are harmful to the human body, but does not affect beneficial elements such as iron, zinc, and copper. Through enzymatic hydrolysis technology, MCP small molecule pectin not only reduces the degree of esterification of pectin, but also reduces the molecular weight of pectin, making the pectin more easily absorbed by the body, thereby more effectively chelating lead that enters the bone tissue and playing a role in Good lead removal effect.

Important differences between the various pectic substances are their molecular structure, methyl ester content and degree of esterification. Therefore, there are many ways to classify pectin: for example, according to solubility; according to the degree of esterification; according to molecular weight; and according to whether the structure has been modified after extraction, it is divided into extracted pectin and modified pectin. Commercial pectins currently on the market are divided into the following categories.

High methoxyl pectin

High methoxyl pectin (HMP) usually has more than 50% of the galactose units esterified, that is, the DE value is >50%, or the methoxyl content (DM value) is between 7.0% and 16.3%. This type of Pectins are all high-ester pectins. High-ester pectin does not react with Ca2+. Its gelation mechanism is due to the interaction of hydrophobic bonds and hydrogen bonds between pectin molecules. Its formation of gel depends on the acid content, pectin type, concentration and soluble solid content. content. Usually, only pectin with a soluble solid content of more than 55% and a pH of 2.0-3.8 will have good gel properties. The gel formed by HMP is thermally irreversible. Mainly used in the food industry as a thickener and stabilizer.

Low methoxyl pectin

The esterified galactose units of low methoxy pectin (LMP) do not exceed 50%, that is, the DE value is <50%, or the methoxy group content (DM value) is <7.0%. This type of pectin even in soluble solids Under very low conditions, it forms a gel with Ca2+. The LMP gel mechanism is due to the large number of free carboxyl groups on the pectin molecules, which makes it difficult to form a gel binding zone. However, it can form a cross-linked structure with divalent or multivalent metal cations, and at the same time neutralizes the intermolecular effects within the pectin. Effect of bound anions. During gelation, divalent or multivalent metal ions are the key to affecting the gel. The pH value requirements are relatively wide compared to methoxy pectin, generally between 2.6-6.8, and are basically not affected by the solid content. The strength of its gel formation depends on the pectin concentration, type, soluble solids content, pH range, buffer concentration and Ca2+ content. Only when the Ca2+ concentration and pectin concentration reach a good balance can the gel quality reach the optimal effect. When Ca2+ exceeds the optimal content, the gel formed will be brittle and the gel will have a tendency to dehydrate. , or form calcium pectate and become an insoluble pectin salt. Because low-ester pectin can form gels at low soluble solids content and high pH, it has good applications in the beverage and dairy industries. Most researchers believe that the combination of low-methoxyl pectin molecules with polyvalent metals is a chelation effect. The chelating properties of low-ester pectin for divalent metal ions are used in medicine to eliminate heavy metals. Current research from Zhejiang University and Zhejiang Guoyuan Kangpin has found that certain sources of low-ester pectin have good effects on anti-hangover and anti-intoxication.

Amidated pectin

When pectin is replaced with ammonia for acid during the deesterification process, the esterified groups are replaced by amide groups, forming amide pectin. The degree of amidation (DA) refers to the percentage of carboxyl groups in the amide form. Most commercial low-ester pectins are amidated, with typical DA values in the range of 15%-22%. Compared with unamidated pectin, amidated pectin can gel at higher temperatures and requires almost no Ca2+. The gelation of unamidated pectin is affected by the automatic fluctuation of the Ca2+ content of the fruit raw materials used, and the gel temperature and gel strength change drastically due to changes in Ca2+ concentration. The gel properties of low methoxyamide pectin are less affected by Ca2+ concentration. Currently, it is mostly used in cooling gel materials and jelly.

Modified citrus pectin

Citrus pectin is a complex polysaccharide long-chain carbohydrate extracted from the pulp and peel of citrus fruits such as lemons, grapefruits, oranges and tangerines, with a molecular weight generally above 100,000. The extracted citrus pectin is a water-soluble dietary fiber. The extracted product has many branches and has strong adhesion function. It specifically kills mutated cells and eliminates them before they are formed; it also prevents the aggregation of mutated cells and the adhesion of mutated cells to neighboring cells and tissues.

Modified Citrus Pectin (MCP) is a product with smaller molecular weight and lower degree of esterification obtained by adjusting the pH and hydrolyzing natural citrus pectin (CP) using acid, alkali and enzyme technologies. , unbranched pectin polysaccharide, the molecular weight is reduced to less than 20,000. Compared with CP, MCP has no fundamental change in its monosaccharide composition. MCP is richer in galacturonic acid, rhamnose and xylose; and MCP has all the physiological functions of CP, but due to the reduced molecular weight, pectin is more Easily absorbed by the body and enters blood circulation. It is currently used in the areas of three highs and anti-cancer, especially in the development of anti-tumor targeted drugs.

Clinical applications of pectin

Pectin has pharmacological effects such as antibacterial, hemostasis, lowering blood lipids, excreting lead, anti-cancer, and anti-alcohol. It can be used alone or in combination with other drugs to treat certain diseases.

In the past 10 years, there have been an increasing number of reports at home and abroad about the use of plant fiber to treat diabetes. Plant fiber plays an important role in the digestion, absorption and metabolism of many nutrients. Experiments have shown that pectin treatment can significantly reduce blood sugar and can be used as a simple and easy auxiliary measure for the treatment of diabetes.

Pectin has the effect of lowering blood lipids, and can be made into granules to treat arteriosclerosis; pectin can reduce the damage to the gastrointestinal membrane caused by anti-cancer drugs, and taking pectin can reduce abdominal discomfort caused by some non-lytic anti-inflammatory drugs.

Company Introduction And Certificates Obtained

Founded in 2014, YTBIO mainly supplies food additives such as Erythritol Powder, herbal extracts, functional cosmetic raw materials, organic products, etc. All of our products are produced by ourselves. At present, our certificates include ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,  etc. All our products have been tested and we support third-party testing. We provide a variety of products, for any detailed information about the products, please click sales@sxytbio.comContact us, we will have professional sales staff to give you detailed answers

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