Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of trichosanthes fruit extract in China. With abundant experience, we warmly welcome you to wholesale bulk trichosanthes fruit extract for sale here from our factory. Quality products and reasonable price are available.
About The Detailed Introduction Of Trichosanthes Extract?
Trichosanthes Fruit Extract is an active substance extracted from the dried and mature fruits of the Trichosantheskirilowii Maxim. or Trichosanthes rosthornii Harms of the Trichosanthes family. It mainly contains oils, sterols, flavonoids, triterpenes, amino acids, proteins and other ingredients.
Trichosanthes trichosanthes has a sweet, slightly bitter, and cold nature and flavor. Enters the lung, stomach and large intestine meridians. It has the effects of clearing away heat and removing phlegm, widening the chest and dispersing stagnation, moistening dryness and smoothing the intestines. It is used for cough due to lung heat, turbid yellow and thick phlegm, chest obstruction and heartache, chest congestion, breast abscess, lung abscess, swollen and painful intestinal abscess, and constipation.
chemical composition
Nearly a hundred compounds were isolated and identified from the extracts of the fruits, peels and seeds of Trichosanthes trichosanthes, which mainly include oils, sterols, flavonoids, triterpenes, amino acids, proteins, etc., and also contain potassium, sodium, calcium, Magnesium, zinc, iron, molybdenum, chromium and other trace elements.
Preparation of main ingredients
Use ultrasonic wave to extract Trichosanthes saponins. Weigh a certain amount of melon basket into a flask → add a certain amount of solvent (alcohol concentration is 40%, solid-liquid ratio is 1:25) → let it stand for a certain period of time → put it in an ultrasonic extractor (ultrasonic time is 50 minutes, Ultrasonic power is 90W) → suction filtration → constant volume → Trichosanthes saponins
What Are The Benefits?
1.Expelling phlegm and relieving cough
The amino acids isolated from Trichosanthes trichosanthes have a good expectorant effect. Cysteine can cleave sputum mucin, making the sputum less viscous and easier to cough up. Aspartic acid can promote the transformation of bone marrow T lymphocyte precursors into mature T lymphocytes, which is beneficial to reducing inflammatory secretions; methionine Can be converted into cysteine and cystine to play a synergistic effect. Research has confirmed that Trichosanthes trichosanthes decoction has a significant expectorant effect and can effectively inhibit coughs caused by ammonia.
2. Antibacterial effect
The aqueous extract of Trichosanthes trichosanthes has a good antibacterial effect. Studies have reported that the water extract of Trichosanthes trichosanthes can inhibit Microsporum audunensis and Nocardia stariformis, promote the growth of photosynthetic bacteria, and can be effective at low concentrations. Studies have shown that Trichosanthes trichosanthes decoction has in vitro effects on Escherichia coli, Bacillus cholera, Bacillus dysentery, Bacillus typhi, Bacillus paratyphoid, Pseudomonas aeruginosa and hemolytic streptococci, pneumococci, diphtheriae, Staphylococcus aureus, influenza bacilli, etc. inhibitory effect.
3. Anti-ulcer effect
Trichosanthes trichosanthes alcohol extract can reduce gastric acid secretion and gastric acid concentration in rats, and has a significant inhibitory effect on ulcers caused by pylorus ligation, gastric damage induced by 5-hydroxytryptamine and water immersion pressure. Among them, 1000 mg/kg Trichosanthes trichosanthes alcohol extract has the most obvious effect on ulcers caused by pylorus ligation, with an inhibition rate as high as 84.1%. At a preventive dose, Trichosanthes trichosanthes alcohol extract can cure gastric ulcers caused by acetic acid, inhibit gastric mucosal damage induced by hydrochloric acid ethanol solution, and alleviate gastric mucosal damage caused by NaOH at a certain concentration. In addition, Trichosanthes trichosanthes alcohol extract has a significant relaxing effect on acetylcholine-induced ileal contraction in mice.
4. Dilation of coronary arteries
The decoction and alcohol precipitation concentrate of Trichosanthes trichosanthes peel and Trichosanthes trichosanthes kernels and the Trichosanthes trichosanthes injection made from Trichosanthes trichosanthes peel can dilate the coronary arteries in the isolated hearts of guinea pigs and significantly increase the coronary flow. The strength of each medicinal part was measured using the guinea pig isolated cardiac perfusion method, and the result was Trichosanthes trichosanthes peel > Trichosanthes trichosanthes seeds. The alkaloids isolated from Trichosanthes melon peel also have the effect of dilating coronary arteries. Trichosanthes trichosanthes injection has a significant protective effect on acute myocardial ischemia in rats caused by pituitaryin.
5. Inhibit platelet aggregation
Citrulonic acid has a concentration-dependent inhibitory effect on platelet aggregation stimulated by collagen, adenosine diphosphate, and epinephrine in vitro. Its inhibitory potency is roughly the same as that of linolenic acid.
6. Anti-hypoxic effect
Intraperitoneal injection of Trichosanthes trichosanthes injection into mice can significantly enhance the mice's tolerance to normal pressure and hypobaric hypoxia. Mice pre-injected with isoprenaline can also significantly increase the anti-hypoxia effect, making the mice more resistant to hypoxia. Increased survival rate under hypobaric hypoxia. However, secobarbital sodium cannot prolong the sleep time of mice and has no inhibitory effect on the central nervous system, which indicates that it has a selective anti-hypoxic effect on the heart. This product can also significantly delay the onset of conjunctival microcirculation disorders caused by hypoxia.
7. Purgative effect
Trichosanthes trichosanthes contains strong purgative substances and has a purgative effect. The fatty oil contained in Trichosanthes melon kernels can also cause diarrhea, so its effect is the strongest, Trichosanthes trichosanthes peel has a weaker effect, and Trichosanthes trichosanthes frost has a milder effect.
8. Improve myocardial ischemia
Trichosanthes Fruit Extract can dilate the coronary arteries of guinea pig hearts and significantly increase coronary flow, showing a certain dose-effect relationship. It can also prolong the survival time of hypoxic mice treated with isoproterenol and increase local SOD during ischemia-reperfusion. activity, reduce the content of malondialdehyde (MDA), and have a protective effect on acute ischemic myocardium in rats caused by pituitrin; it can also reduce the accumulation of free fatty acids (FFA) in ischemic myocardium and improve ischemic myocardium. The metabolism of FFA protects membrane enzyme activity, thereby protecting ischemic myocardium.
9.Other functions
Trichosanthes trichosanthes extract also has a certain impact on serum cholesterol and blood sugar. Trichosanthes trichosanthes peel extract can reduce total cholesterol in rat serum and has a protective effect on arteriosclerosis in rats caused by hyperlipidemia; studies have shown that trichosanthes trichosanthes extract has a certain inhibitory effect on α-glucosidase, and its extract can significantly It significantly increases the blood sugar level of hungry rabbits, but does not affect the contents of liver glycogen and muscle glycogen; cell experiments and animal experiments prove that trichosanthin agglutinin has a strong hypoglycemic effect.
What Are The Application Directions?
Medical field: Trichosanthes Fruit Extract is widely used in the medical field. Its cucurbitacin has various effects such as blood pressure lowering, hypoglycemic, antibacterial, anti-tumor, anti-inflammatory, antipyretic, etc., and can be used to treat hypertension, hyperglycemia, infectious diseases, tumors, etc. In addition, Trichosanthes melon extract can also be used as a health product to supplement vitamin C and other nutrients and improve the body's immunity.
Food processing field: It is also widely used in food processing field. Trichosanthes trichosanthes extract can be used as a natural food additive and added to various foods, such as beverages, pastries, soy products, etc., to enhance the nutritional value and taste of food.
Beauty and health care field: It can also be used as one of the main ingredients of beauty and health care products. It can be used to make facial masks, shampoo, shower gel and other skin care products. It has the effects of regulating skin pigment, removing facial spots, reducing dark circles, and promoting hair growth.
Other fields: also used in other fields. For example, in the field of agriculture, Trichosanthes trichosanthes extract can be used as a natural plant pesticide to prevent and control crop pests; in the field of environmental management, Trichosanthes trichosanthes extract can also be used as an adsorbent for heavy metal pollutants and used to treat wastewater. and exhaust fumes.
Company Introduction And Certificates Obtained
Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Trichosanthes Fruit Extract etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.
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