Bupleurum Root Extract

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of bupleurum root extract in China. With abundant experience, we warmly welcome you to wholesale bulk bupleurum root extract for sale here from our factory. Quality products and reasonable price are available.

 

Bupleurum Root Extract is a fine brown powder derived from the dried roots or whole plants of *Bupleurum chinense* DC. or *B. scorzonerifolium* Willd. Medicinal Bupleurum is commonly categorized into northern and southern varieties. The primary active constituents are total Bupleurum saponins, which serve to harmonize the exterior and interior of the body and to clear the liver while relieving stagnation. Pharmacological studies indicate that Bupleurum also exhibits antipyretic, analgesic, sedative, anticonvulsant, hepatoprotective, anti-inflammatory, and anti-ulcer effects, as well as the ability to enhance immune function.

1. Total Saponins of *Bupleurum*

Total saponins are the most abundant and representative core active constituents of *Bupleurum* extract. Composed primarily of various monomeric saponins, they serve as the fundamental basis for the extract's biological activity.

2. Flavonoids

*Bupleurum* extract is rich in a diverse range of flavonoids, primarily including common monomers such as quercetin, rutin, and kaempferol.

3. Polysaccharides

Polysaccharides are key water-soluble active constituents in *Bupleurum* that act synergistically with saponins and flavonoids.

1. Antipyretic effect
The active ingredients of Bupleurum extract are Bupleurum volatile oil (eugenol, caproic acid, r-undecanoic acid lactone and p-methoxybenzenedione), which has inhibitory and killing effects on pathogens, so it is effective in typhoid and paratyphoid vaccines. E. coli liquid, fermented milk, yeast, etc. have obvious antipyretic effect; and can reduce the normal body temperature of animals.
2. Anti-inflammatory effect
Saikosaponin has a significant inhibitory effect on a variety of inflammatory processes, including inflammatory exudation, increased capillary permeability, release of inflammatory mediators, migration of leukocytes, connective tissue hyperplasia and various allergic inflammations.
3. Antiviral effect
Bupleurum extract has strong antiviral activity and can significantly inhibit influenza virus in chicken embryos, reduce the increase in lung index caused by mouse pneumonia virus, prevent exudative lesions of lung tissue, and reduce the death of mice caused by pneumovirus. rate.
4. Hepatoprotective effect
The hepatoprotective activity of saikosaponin is mainly manifested in the following aspects: ① Reduce the activity of cytochrome P450, protect liver cells from necrosis, and promote liver cell regeneration; ② Stimulate the pituitary adrenocortical system and increase the secretion of endogenous glucocorticoids; ③ Reduce the coenzyme cytochrome C reductase activity of dehydrogenase and reduce hormone-like side effects; ④ activate giant cells and promote the production of antibodies and interferons; ⑤ promote protein synthesis, increase liver glycogen, reduce peroxidized lipids, and promote Liver cell regeneration; ⑥ Enhance the activity of NK cells and LAK. Saikosaponin also inhibits cholinesterase and prevents acetylcholine from being hydrolyzed by cholinesterase, thereby regulating the functions of the digestive system and nervous system, thereby treating liver stagnation syndrome and soothing the liver and relieving stagnation.
5. Hypolipidemic effect
Saikosaponin can significantly reduce the experimental increase in serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol in mice, and inhibit the formation of experimental hyperlipidemia in mice, so it can effectively prevent and treat atherosclerosis.
6. Anticonvulsant effect
The reasonable combination of saikosaponin and volatile oil has a strong anticonvulsant effect, and has a significant inhibitory effect on the cerebral cortical discharge and synaptic transmission process of the central nervous system in epilepsy models. That is, the Bupleurum extract has a significant inhibitory effect on epilepsy. function.
7. Anti-drunk effect
Bupleurum extract can induce the activity of liver enzymes, accelerate the decomposition and oxidation of ethanol in the body, thereby reducing the concentration of ethanol in body fluids (including blood). With the same amount of drinking, it can reduce the concentration of ethanol in various tissues in the body, especially the brain. Ethanol concentration in tissues. This is one of the mechanisms of the anti-intoxication effect of Bupleurum extract.

Pharmaceutical field:
It is often used in traditional Chinese medicine preparations, such as Bupleurum injection, Bupleurum tablets, Bupleurum granules, etc. It contains a variety of active ingredients, such as bupleurum, bupleurum ester, bupleurum lactone, etc., which have sedative, antipyretic, anti-inflammatory and other effects. In traditional Chinese medicine, Bupleurum extract is often used to treat liver qi stagnation, colds, fever, jaundice and other symptoms. It has certain effects on improving mood and regulating liver qi.

Health care products field:
Bupleurum root extract is also widely used in the field of health products. It is used to make health products such as Bupleurum oral liquid and Bupleurum capsules, and is often recommended to people who need to regulate mood, improve sleep quality, and relieve anxiety. Bupleurum extract has a calming and soothing effect, which can help relieve stress and promote sleep.

Cosmetics field:
Also used in cosmetics. It can be used in skin care products due to its antioxidant, anti-inflammatory, and antibacterial properties. For example, Bupleurum extract is often added to products such as facial masks, lotions, and essences to regulate skin balance, reduce inflammation, and improve skin texture.

others:
There are other applications as well. For example, in the food industry, Bupleurum extract can be used as a flavoring agent to give food a certain bitter taste and aroma. In addition, Bupleurum extract can also be used in the agricultural field as a plant growth regulator to promote plant growth and enhance plant stress resistance.

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Bupleurum root extract etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,  and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

Contact us now for Bupleurum Root Extract samples, technical information, and customized quotes.

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