Ergothioneine Powder

Shaanxi Yuantai Biological Technology Co., Ltd. is one of the most reliable manufacturers and suppliers of ergothioneine powder in China. With abundant experience, we warmly welcome you to wholesale bulk ergothioneine powder for sale here from our factory. Quality products and reasonable price are available.

What is ergothioneine?

Ergothioneine powder is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic, and have become a research hotspot. As a natural antioxidant, ergothioneine has entered people's field of vision. It has various physiological functions such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity.

Ergothioneine (mercaptohistidine trimethyl internal salt, ergothioneine, EGT) is a compound discovered in 1909. It was first discovered in a fungus, Claviceps purpurea. The pure product is white crystal, water-soluble, (at room temperature Soluble 0.9mol/L), it will not oxidize itself under physiological pH value and strong alkaline solution.

Ergothioneine is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic and have become a hot research topic. Ergothioneine, as a natural antioxidant, has entered people's field of vision. It has many physiological functions such as scavenging free radicals, detoxifying, maintaining DNA biosynthesis, normal cell growth and cellular immunity.

In addition, studies have shown that ergothioneine can also inhibit the activity of mitochondrial complex II, thereby protecting mitochondria. In short, ergothioneine is an important bioactive substance with multiple physiological functions, including antioxidant and anti-inflammatory effects.

Product Details Form

What are the benefits?

Anti-oxidize effect

Studies have shown that a certain concentration of ergothioneine in the body can act as an antioxidant.

Protective effect on cells

Ergothioneine is a powerful hypochlorous acid scavenger (HOCl), and while many compounds react with hypochlorous acid, few react as rapidly as ergothioneine.

Anti-inflammatory effect

Ergothioneine powder can inhibit peroxynitrite-mediated amino acid oxidation, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.

Other biological functions

Transport cations and catalysis of carbon dioxide carboxylation or decarboxylation reactions;

Modulate histamine or antihistamine effects;

Choline-like function or anti-parasympathetic neurophysiological effect; can modulate the reactivity of other acyl carriers or itself as an acid-based carrier.

Metabolism

Ergothioneine can boost metabolism

Anti-oxidize effect

A large number of studies have shown that ergothioneine has strong antioxidant capabilities. Ergothioneine is a highly effective scavenger of singlet oxygen, superoxide ions, hydrogen peroxide, lipid peroxides, nitric oxide derivatives and hydroxyl radicals. Its antioxidant mechanism in the body has not yet been fully elucidated. Ergothioneine chelates various divalent metal cations such as Cu2+, Hg2+, Zn2+, Cd2+, Fe2+, Ni2+, etc. to form a complex with no redox activity, preventing these metal ions from participating in the activity. For the production of oxygen, ergothioneine can regulate the antioxidant enzyme system, activate antioxidant enzymes, such as glutathione peroxidase, superoxide dismutase, and catalase, and maintain reduced glutathione and oxidized glutathione. Glutathione ratio, inhibiting super oxidative kinase, ergothioneine also combats reactive oxygen species produced when hydrogen peroxide interacts with hemoglobin and myoglobin.

Anti-inflammatory effect

Ergothioneine has anti-inflammatory properties and its potential to modulate pro-inflammatory cytokines. Ergothioneine can effectively inhibit the activation of the NF-κB gene signaling pathway and slow down the release of inflammatory factors such as IL-8β. Ergothioneine can also inhibit the expression of IL-8β, IL-6β and other genes and inhibit inflammatory responses. Ergothioneine dose-dependently inhibits the synthesis of pro-inflammatory cytokines IL-6 and IL-8 and prevents cell death by inhibiting the expression of pro-apoptotic factors Bax and caspase-3. Ergothioneine significantly reduces lung and intestinal ischemia-reperfusion injury by reducing serum IL-1β and TNF-α levels.

Anti-nerve damage effect

Both in vivo and in vitro experiments have shown that EGT has certain effects on the development, maintenance and antagonism of damage to the nervous system. Ergothioneine can promote the differentiation of neuronal stem cells, inhibit brain damage caused by β-amyloid accumulation or D-galactose, slow down mitochondrial dysfunction of nerve cells, and protect neuronal damage. Ergothioneine accumulation in the brain helps reduce oxidative stress and neuroinflammation, potentially reducing signs or symptoms of neurological disease.

Application direction

For substances with significant and unique biological functions of ergothioneine, scholars from various countries have carried out research on its application for a long time. Although it still needs to be further deepened, it is very enlightening for its application in various fields. Ergothioneine has a wide range of uses and market prospects in the fields of cell preservation, food and beverage, functional food, animal feed, cosmetics and biotechnology.

Added to cosmetics as a skin protectant

Ergothioneine powder can minimize the formation of reactive oxygen species and protect cells from radiation damage. Therefore, ergothioneine can be added to certain cosmetics as a skin protectant for the development of outdoor skin care products and protective cosmetics.

Application of ergothioneine in food

Ergothioneine can be used as a dietary supplement in food. Spirulina is known as the "best food of the future" and can lower blood lipids, improve immunity and other physiological activities. Ergothioneine can inhibit the damage caused by various diseases to human cells and tissues. It can be regarded as an important vitamin in the human body and can be used as an ingredient in dietary functional foods. Some researchers used deep fermentation of edible fungi to synthesize mycelium rich in ergothioneine, and prepared functional oral liquid rich in ergothioneine. This product is suitable for people with unhealthy diets, smokers, athletes, people with memory loss, and patients with chronic inflammation and arthritis. It can reduce inflammation, relieve pain, and supplement energy. Due to its antioxidant properties and ability to chelate metal ions, ergothioneine can be used as an additive in food, beverages, and pharmaceutical products. Ergothioneine is non-toxic, colorless and odorless, and has better thermal stability and pH stability than Vc.

Application of ergothioneine in cosmetics

Keratinocytes, fibroblasts and melanocytes in human epidermal cells can all express ergothioneine transporters and can absorb and accumulate ergothioneine. Ergothioneine has an absorption wavelength similar to that of DNA in the ultraviolet absorption range, and can effectively protect against cell damage caused by ultraviolet radiation. At the same time, ergothioneine also has antioxidant ability. Under continuous ultraviolet irradiation for 18 hours, 70% of cells are still reducing, inhibiting lipid peroxidation, preventing the generation of reactive oxides, and reducing the risk of stress. Apoptosis of irradiated cells. Ergothioneine has good chemical stability and is non-toxic when accumulated in epidermal cells. Therefore, it has very broad application prospects in the cosmetics industry. It can be used for whitening, removing wrinkles, delaying aging, removing acne, and preventing hair loss.

Application of ergothioneine in the pharmaceutical field

Ergothioneine is the only natural antioxidant that can chelate metal ions while preventing tissue red blood cells from being damaged by reactive oxidants. When the concentration reaches mmol/L in the tissue, it can stimulate the cells' natural antioxidant defense system. Due to the antioxidant and anti-inflammatory activities of ergothioneine, it can inhibit a variety of diseases caused by oxidative damage, such as heart disease, myalgia and even premature aging. Especially due to the existence of ergothioneine transporters, ergothioneine has superior physiological properties than glutathione in some aspects. For example, ergothioneine and ergothioneine transporters can treat autoimmune thrombocytopenia, acute rheumatoid arthritis, thyroid disease, etc.

Company introduction and certificates obtained

Shaanxi Yuantai Biotechnology Co., Ltd. was established in 2014, mainly supplying herbal extracts, functional cosmetic raw materials, organic products, etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA and other certificates. 

Our packaging

1KG/Aluminium bags , 25kg/barrel

Storage: Store in a cool, dry, clean place away from moisture and direct light.

We also have special packaging for special products, such as: retinal - cold chain transportation; deoxyarbutin - vacuum transportation

Our team

We have a professional R&D team and sales team, which not only ensure product quality, but also ensure a good cooperation experience for customers in the pre-sale, in-sale and after-sale processes. Our sales team has been trained in professional product knowledge, and can respond and solve every problem in cooperation in a timely manner

Factory

Payment method

The payment methods we support are: T/T, VISA, XTransfer, Master Card, Western Union, Alibaba Payment, e-Checking, Online Bank Payment

Shipping method

We support shipping by sea, air, DHL, FedEx, TNT, UPS, EMS, SF

Hot Tags: ergothioneine powder, China ergothioneine powder manufacturers, suppliers, factory